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Longer time in bed after stroke linked to poorer brain health

After a mild stroke or transient ischemic attack (TIA), people who spend more time in bed sleeping or trying to sleep may be more likely to have lower scores on tests of thinking and memory skills and changes in their brains that can lead to dementia or second strokes, according to a study published on May 28, 2025, online in Neurology, the medical journal of the American Academy of Neurology.

28 May 2025

Stress granules play a protective role against neurodegenerative disease

Scientists from St. Jude Children's Research Hospital and Washington University in St. Louis report mechanistic insights into the role of biomolecular condensation in the development of neurodegenerative disease.

28 May 2025

Researchers find way to protect mitochondria from stress-induced damage

Mitochondria are the cell's power plants: They turn the food we eat into the energy our cells can use. But when stress hijacks the process they use to maintain their quality, they get snipped into useless fragments and go into a tailspin that spreads from cell to cell and triggers a wide range of human diseases.

26 May 2025

Novel immune cells identified as potential target for tuberculosis vaccines

There is no highly effective vaccine against tuberculosis (TB), which remains an infection of global concern.

26 May 2025

Catalpol shows neuroprotective effects across multiple neurologic conditions

Announcing a new publication for Acta Materia Medica journal. Neurologic disorders are the leading cause of illness and disability as a result of increased life expectancy and global population aging, highlighting the urgent need and great challenge for discovering neuroprotective agents with better efficacy and minimal side-effects.

22 May 2025

Study assures safety of triptan use during pregnancy for migraine sufferers

There's good news for people with migraine who take common drugs before or during pregnancy-a new study found no increase in neurodevelopmental disorders such as autism and ADHD in their children.

22 May 2025

New gene delivery systems can reach cells in the brain and spinal cord with exceptional accuracy

Research teams funded by the National Institutes of Health (NIH) have created a versatile set of gene delivery systems that can reach different neural cell types in the human brain and spinal cord with exceptional accuracy.

21 May 2025

REM sleep suppression linked to longer survival in ALS patients

During REM sleep, the body enters a state of paralysis. This can pose a danger for patients with weakened diaphragms due to neuromuscular diseases.

21 May 2025

New Alzheimer's drug candidate reduces toxic protein and improves memory in mice models

As researchers work to improve treatment of Alzheimer's disease, new research by UCLA Health identified a candidate drug that reduces levels of a toxic form of a protein in the brain caused by the disease and improved memory in mice by boosting production of a protective protein.

20 May 2025

Scientists discover how EBV-infected immune cells migrate and invade the brain

Many people are infected with the Epstein-Barr virus (EBV), and most are unaware of it. However, EBV can sometimes cause cancer, and this pathogen also appears to play an important role in multiple sclerosis and other autoimmune diseases.

19 May 2025

New short film sheds light on the impact of climate change on brain health

A powerful new short film, from the FutureNeuro Research Ireland Centre and RCSI University of Medicine and Health Sciences sheds light on the urgent need to address the impact of climate change on brain health.

19 May 2025

Peptide nanostructures block amyloid buildup and boost neuron survival in lab tests

Researchers developed trehalose-functionalized peptide amphiphiles (TPAs) that self-assemble into supramolecular nanostructures and demonstrated these TPAs can inhibit amyloid beta aggregation. In vitro, TPAs significantly improved survival of human neurons exposed to amyloid-induced neurotoxicity, suggesting therapeutic potential for neurodegenerative diseases.

15 May 2025

AAN releases Evidence in Focus Article on new gene therapy for Duchenne muscular dystrophy

To help neurologists, clinicians and families understand the current evidence for a new gene therapy for Duchenne muscular dystrophy called delandistrogene moxeparvovec, the American Academy of Neurology (AAN) has issued an Evidence in Focus article, published May 14, 2025, online in Neurology.

14 May 2025

Mini-stroke patients may experience fatigue for up to a year

A transient ischemic attack, also known as a mini-stroke, is typically defined as a temporary blockage of blood flow to the brain that causes symptoms that go away within a day, but a new study finds that people who have this type of stroke may also have prolonged fatigue lasting up to one year.

14 May 2025

New approach directly combats the progression of Alzheimer’s and ALS

Scientists at Northwestern University have developed a new approach that directly combats the progression of neurodegenerative diseases like Alzheimer's disease and amyotrophic lateral sclerosis (ALS).

14 May 2025

Mitochondrial DNA editing offers new hope for neurodegenerative disease treatment

Mitochondrial DNA (mtDNA) editing has emerged as a revolutionary approach in the fight against neurodegenerative diseases (NDDs).

12 May 2025

Estrogen-related receptors could be a key to repairing energy metabolism and muscle fatigue

A new Salk Institute study suggests estrogen-related receptors could be a key to repairing energy metabolism and muscle fatigue.

12 May 2025

High intake of ultra processed foods linked to early signs of Parkinson's

People who eat more ultra processed foods like cold breakfast cereal, cookies and hot dogs are more likely to have early signs of Parkinson's disease when compared to those who eat very few ultra processed foods, according to a study published in the May 7, 2025, online in Neurology, the medical journal of the American Academy of Neurology.

7 May 2025

Study links sleep apnea to damage in brain areas critical for memory

Obstructive sleep apnea, a condition that causes lower oxygen levels during sleep, is linked to degeneration of brain regions associated with memory through damage to the brain's small blood vessels, according to a study published May 7, 2025, online in Neurology, the medical journal of the American Academy of Neurology.

7 May 2025

Cardiovascular mortality higher in women with rheumatoid arthritis and lupus

Women with the autoimmune diseases rheumatoid arthritis, lupus or systemic sclerosis may have a higher rate of death related to cardiovascular disease than men with the autoimmune diseases, according to new research published in the American Heart Association's journal Circulation: Cardiovascular Quality and Outcomes.

6 May 2025