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Interventions based on Choosing Wisely guidelines can reduce antibiotic overuse at safety-net hospitals

A statewide pay-for-performance intervention based on a set of guidelines called Choosing Wisely reduced rates of inappropriate antibiotic prescriptions to treat acute respiratory tract infections by an average of 18 percentage points, from 43% to 25%, across two large Los Angeles safety net hospitals.

12 Jun 2023

Combining blood biomarkers with genomics could provide useful information about disease risk

Being to identify people at high risk of chronic disease means that they can be targeted with prevention measures before they become sick.

9 Jun 2023

Study reveals insights into the relationship between peer comparison and job satisfaction among clinicians

Showing people how their behavior compares to their peers is a commonly used method to improve behavior. But in the wake of a global pandemic that exacerbated health care providers' job dissatisfaction and burnout, questions remain about the potentially negative effects of peer comparison on the well-being of clinicians.

9 Jun 2023

Insilico Medicine nominates pan-TEAD inhibitor as a potential solution for drug resistance in solid tumor patients

Insilico Medicine, a generative artificial intelligence (AI)-driven clinical-stage drug discovery company, today announced the nomination of ISM6331, a potential best-in-class pan-TEAD inhibitor, as a preclinical candidate compound (PCC) generated by Chemistry42, its proprietary generative chemistry-driven molecule design engine, targeting the Hippo pathway for the treatment of advanced solid tumors.

8 Jun 2023

Scientists identify the IL-17 protein as a determining factor in skin aging

A team of scientists from the Institute for Research in Biomedicine (IRB Barcelona) in collaboration with the National Center for Genomic Analysis (CNAG) has discovered that IL-17 protein plays a central role in skin aging.

8 Jun 2023

Massage therapists ease the pain of hospice patients — but aren’t easy to find

Ilyse Streim views massage for people in hospice care as “whispering to the body through touch.”

8 Jun 2023

Study analyzes the prevalence of osteoporosis in postmenopausal women

Osteoporosis is a degenerative, debilitating bone disease that is increasingly prevalent in postmenopausal women.

8 Jun 2023

Level of fat within the body's muscle may lead to risk of cognitive decline while aging

New research reveals that the level of fat within the body's muscle - or muscle adiposity - may indicate a person's likelihood of experiencing cognitive decline as they age.

8 Jun 2023

Study reveals surprising link between biological age and child development

Study explores the relationship between accelerated biological age in children, as indicated by telomere length and DNA methylation age, and various developmental outcomes. It aims to clarify the impact of accelerated biological age on growth, cognition, behavior, lung function, and puberty onset in European school-age children.

7 Jun 2023

DNAmFitAge: A new method to incorporate physical fitness into epigenetic clocks

A new research paper was published in Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science) Volume 15, Issue 10, entitled, "DNAmFitAge: biological age indicator incorporating physical fitness."

7 Jun 2023

Study explores link between social participation and successful aging in later life

A new study followed more than 7000 middle aged and older Canadians for approximately three years to understand whether higher rates of social participation were associated with successful aging in later life.

7 Jun 2023

Study highlights the urgent need for a higher level of care for nursing home residents with AD

The quality of care for nursing home residents with Alzheimer's disease and related dementias is best when they are in the majority, but most facilities also accommodate a heterogeneous population, where specialized staff training is limited, according to a study led by the University of California, Irvine.

7 Jun 2023

CBD and EPA cream: Dynamic duo for youthful skin

A recent study examines the anti-aging potential of a new cream formulation that contains CBD and EPA.

6 Jun 2023

The association of youth, adulthood, and long-term dietary patterns from youth to adulthood with cognitive function in midlife

A study evaluated the association between long-term dietary patterns from youth to adulthood and cognitive function in midlife.

6 Jun 2023

Is there radiographic evidence of premature brain aging in individuals with type 1 diabetes?

Researchers identified brain regions most affected in middle-aged and older adults with type I diabetes.

6 Jun 2023

Researchers test nitroglycerin patch as treatment for menopausal women experiencing hot flashes

Women have long searched for remedies for the bothersome hot flashes that often come with menopause.

5 Jun 2023

Scientists develop AI-based method to visualize and track changes in the strength of synapses

Johns Hopkins scientists have developed a method involving artificial intelligence to visualize and track changes in the strength of synapses — the connection points through which nerve cells in the brain communicate — in live animals.

5 Jun 2023

Neighborhood deprivation and depressive symptoms linked to premature aging

Feeling depressed and living in a deprived urban neighborhood could be making you age faster, according to a new study led by researchers at McMaster University.

5 Jun 2023

Women taking oral estrogen therapy more likely to develop high blood pressure

Women ages 45 years and older taking estrogen hormone therapy in pill form were more likely to develop high blood pressure than those using transdermal (topical, applied to the skin) or vaginal formulations, according to new research published today in Hypertension, a peer-reviewed American Heart Association journal.

5 Jun 2023

Improving prostate cancer screening: accounting for genetic determinants of PSA variation

Researchers conducted a genome-wide analysis of prostate-specific antigen (PSA) levels of men without prostate cancer.

5 Jun 2023

Aging News and Research

Interventions based on Choosing Wisely guidelines can reduce antibiotic overuse at safety-net hospitals

Combining blood biomarkers with genomics could provide useful information about disease risk

Study reveals insights into the relationship between peer comparison and job satisfaction among clinicians

Insilico Medicine nominates pan-TEAD inhibitor as a potential solution for drug resistance in solid tumor patients

Scientists identify the IL-17 protein as a determining factor in skin aging

Massage therapists ease the pain of hospice patients — but aren’t easy to find

Study analyzes the prevalence of osteoporosis in postmenopausal women

Level of fat within the body's muscle may lead to risk of cognitive decline while aging

Study reveals surprising link between biological age and child development

DNAmFitAge: A new method to incorporate physical fitness into epigenetic clocks

Study explores link between social participation and successful aging in later life

Study highlights the urgent need for a higher level of care for nursing home residents with AD

CBD and EPA cream: Dynamic duo for youthful skin

The association of youth, adulthood, and long-term dietary patterns from youth to adulthood with cognitive function in midlife

Is there radiographic evidence of premature brain aging in individuals with type 1 diabetes?

Researchers test nitroglycerin patch as treatment for menopausal women experiencing hot flashes

Scientists develop AI-based method to visualize and track changes in the strength of synapses

Neighborhood deprivation and depressive symptoms linked to premature aging

Women taking oral estrogen therapy more likely to develop high blood pressure

Improving prostate cancer screening: accounting for genetic determinants of PSA variation

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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