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Promising new strategy to combat fungal infections

A group of Brazilian researchers has found a potential target for novel therapeutic strategies to combat fungal infections – more specifically, those caused by Aspergillus fumigatus. An article reporting the discovery is published in the journal Communications Biology.

5 Sep 2024

Combined use of insulin and metformin enhances diabetic foot ulcer healing, research shows

People with chronic diabetic foot ulcers could soon have a new way to treat their wounds for faster healing and fewer hospital stays.

4 Sep 2024

Anti-coagulant therapy fails to improve stroke outcomes in major study

Stroke patients who survive a blood clot in the brain's blood vessels are prone to developing new blockages during their recovery periods, even if they receive vessel-clearing interventions.

4 Sep 2024

Understanding the hormonal paradox in prostate cancer progression

A treatment paradox has recently come to light in prostate cancer: Blocking testosterone production halts tumor growth in early disease, while elevating the hormone can delay disease progression in patients whose disease has advanced.

4 Sep 2024

Key insights into cardiac metabolism dysfunction in the elderly

A new editorial was published in Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science), Volume 16, Issue 16 on August 19, 2024, entitled, "Cardiac metabolism in the elderly: effects and consequences."

4 Sep 2024

Novel intermediate form of serotonin receptor identified as therapeutic target for psychiatric disorders

Misha Kudryshev's lab at the Max Delbrück Center has identified a molecular intermediate of a serotonin receptor that is involved in diseases such as depression and schizophrenia.

4 Sep 2024

Semaglutide does not increase risk of depression or suicidal thoughts

Taking the weight loss medication semaglutide did not increase the risk of depressive symptoms, suicidal thoughts, or suicidal behavior in persons without known major mental health disorders, according to a new study led by researchers from the Perelman School of Medicine at the University of Pennsylvania published this week in JAMA Internal Medicine.

4 Sep 2024

Study reassures patients about semaglutide safety

4 Sep 2024

CDK4/6 inhibitors show promise for pediatric high-grade glioma treatment

CDK4/6 inhibitors, which are already FDA approved for the treatment of other forms of cancer, show early signs of promise in the treatment of a subtype of pediatric high-grade glioma, according to new research from Dana-Farber Cancer Institute and the Institute of Cancer Research in London.

3 Sep 2024

Ketamine clinics show inconsistent practices on pregnancy and contraception

More hospitals and clinics now offer patients ketamine therapy for severe depression, post-traumatic stress disorder and other mental health conditions that haven't responded to other treatments.

3 Sep 2024

Delayed antiviral treatment still beneficial for immunocompromised COVID-19 patients

Starting antiviral treatment as late as 14 days after infection with SARS-CoV-2 may still be beneficial in hosts with compromised immune systems, who are at greatest risk of developing severe COVID-19, according to researchers in the Center for Translational Antiviral Research at Georgia State University's Institute for Biomedical Sciences.

3 Sep 2024

Major trial to test multiple drugs for progressive supranuclear palsy

A clinical trial that will test three drugs concurrently, and could include more, represents new hope for patients with progressive supranuclear palsy (PSP), an incurable neurodegenerative disorder that usually kills within seven years after symptoms start.

3 Sep 2024

Sweat-powered wearable enables continuous health monitoring from the fingertip

A sweat-powered wearable has the potential to make continuous, personalized health monitoring as effortless as wearing a Band-Aid.

3 Sep 2024

European Society of Cardiology highlights underrecognized link between obesity and heart disease

Obesity is a key factor in cardiovascular disease, prompting the ESC to recommend comprehensive strategies for prevention and management to reduce health risks.

3 Sep 2024

Study finds no added benefit of extensive ablation for persistent atrial fibrillation

In patients with persistent atrial fibrillation (AF), standard treatment with pulmonary vein isolation (PVI) ablation resulted in similar outcomes to more extensive ablation in other areas of the heart.

2 Sep 2024

Catheter ablation proven effective for atrial fibrillation in new study

A catheter ablation procedure widely used to treat the most common heart rhythm disorder significantly reduces the burden of atrial fibrillation (AF) and results in clinically important improvements in symptoms and quality of life compared with a sham (placebo) procedure, according to late breaking research presented in a Hot Line Session at this year's ESC Congress 2024 in London, UK (30 Aug - 2 Sept).

2 Sep 2024

Is semaglutide use during breastfeeding safe?

Researchers found no detectable levels of semaglutide in breast milk, suggesting minimal risk to breastfed infants, but highlighted the need for monitoring maternal nutrition and milk production.

2 Sep 2024

NCCS study uses exosomes to overcome resistance to epidermal growth factor receptor inhibitors

In a new study, clinician-scientists and researchers from the National Cancer Centre Singapore (NCCS) have demonstrated the use of exosomes to successfully target squamous cell cancer tumours that are usually resistant to epidermal growth factor receptor-tyrosine kinase inhibitors (EGFR-TKIs). Their research is the first where exosomes have been applied to target TKI-resistant cancers in Singapore. The findings were published in the journal Developmental Cell last month.

2 Sep 2024

Fermented lingonberry juice shown to reduce inflammation and support gut health in IBD

Fermented lingonberry juice may help manage inflammatory bowel disease (IBD) by modulating both the oral and gut microbiomes, reducing inflammation, and promoting beneficial bacteria.

2 Sep 2024

Triple-pill combination GMRx2 outperforms standard care in lowering blood pressure

New research shows that a treatment plan based on novel combination of low doses of three anti-hypertensive drugs in a single pill - known as GMRx2 - was superior to a high-quality standard care treatment plan at lowering blood pressure in patients with uncontrolled hypertension.

1 Sep 2024

Drugs News and Research

Promising new strategy to combat fungal infections

Combined use of insulin and metformin enhances diabetic foot ulcer healing, research shows

Anti-coagulant therapy fails to improve stroke outcomes in major study

Understanding the hormonal paradox in prostate cancer progression

Key insights into cardiac metabolism dysfunction in the elderly

Novel intermediate form of serotonin receptor identified as therapeutic target for psychiatric disorders

Semaglutide does not increase risk of depression or suicidal thoughts

Study reassures patients about semaglutide safety

CDK4/6 inhibitors show promise for pediatric high-grade glioma treatment

Ketamine clinics show inconsistent practices on pregnancy and contraception

Delayed antiviral treatment still beneficial for immunocompromised COVID-19 patients

Major trial to test multiple drugs for progressive supranuclear palsy

Sweat-powered wearable enables continuous health monitoring from the fingertip

European Society of Cardiology highlights underrecognized link between obesity and heart disease

Study finds no added benefit of extensive ablation for persistent atrial fibrillation

Catheter ablation proven effective for atrial fibrillation in new study

Is semaglutide use during breastfeeding safe?

NCCS study uses exosomes to overcome resistance to epidermal growth factor receptor inhibitors

Fermented lingonberry juice shown to reduce inflammation and support gut health in IBD

Triple-pill combination GMRx2 outperforms standard care in lowering blood pressure

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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