Asthma News and Research

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Asthma is a common inflammatory disease affecting the airways that leads to shortness of breath, coughing and wheezing. Symptoms range from mild to severe but are generally manageable with appropriate treatment.

Better understanding of cells' development has implications in study of inflammatory diseases

Labs around the world, and a core group at Penn, have been studying recently described populations of immune cells called innate lymphoid cells. Some researchers liken them to foot soldiers that protect boundary tissues such as the skin, the lining of the lung, and the lining of the gut from microbial onslaught. They also have shown they play a role in inflammatory disease, when the body's immune system is too active.

15 May 2013

LDL cholesterol blood level declines found to have abruptly ended in 2008

Decades of declines in LDL cholesterol blood levels, a key marker of death risk from heart disease, abruptly ended in 2008, and may have stalled since, according to a multi-year, national study published in PLOS ONE.

From Quest Diagnostics 14 May 2013

More than 80% of parents, grandparents prefer hospital that does medical research about children: Study

Four out of five parents and grandparents in Michigan say they'd rather take children to a hospital that does medical research for children than one that does not, according to a new poll from the University of Michigan.

14 May 2013

Breo Ellipta gets FDA approval for treatment of airflow obstruction in patients with COPD

The U.S. Food and Drug Administration today approved Breo Ellipta (fluticasone furoate and vilanterol inhalation powder) for the long-term, once-daily, maintenance treatment of airflow obstruction in patients with chronic obstructive pulmonary disease, including chronic bronchitis and/or emphysema.

13 May 2013

COPD patients with allergic phenotype have increased risk of lower respiratory symptoms, exacerbations

Patients with chronic obstructive pulmonary disease (COPD) who also have allergic disease have higher levels of respiratory symptoms and are at higher risk for COPD exacerbations, according to a new study from researchers at Johns Hopkins University in Baltimore.

10 May 2013

Research finds sharp rise of dementia, other neurological deaths in people under 74

Professor Colin Pritchard's latest research published in Public Health Journal has found that the sharp rise of dementia and other neurological deaths in people under 74 cannot be put down to the fact that we are living longer - the rise is because a higher proportion of old people are being affected by such conditions, and what is really alarming, it is starting earlier and affecting people under 55 years.

10 May 2013

Nearly 5 million asthmatics with ABPA could benefit from antifungal treatment, say researchers

An estimated 4,837,000 asthmatics with allergic bronchopulmonary aspergillosis (ABPA) could benefit substantially from antifungal treatment, say researchers from the University of Toronto and Manchester University.

9 May 2013

Rigel reports net loss of $25.6 million in first quarter 2013

Rigel Pharmaceuticals, Inc. today reported financial results for the first quarter ended March 31, 2013. For the first quarter of 2013, Rigel reported a net loss of $25.6 million, or $0.29 per share, compared to a net loss of $23.2 million, or $0.32 per share, in the first quarter of 2012. Weighted average shares outstanding for the first quarters of 2013 and 2012 were 87.1 million and 71.4 million, respectively.

7 May 2013

Kinase inhibitors: an interview with Jan Hoflack, CSO of Oncodesign

Kinase inhibitors are molecules that block the activity of kinases. Kinases are a specific class of enzymes. They are extremely important in signal transduction processes in the human body meaning that they actually regulate most of the physiological processes that take place in the body.

7 May 2013

New report highlights factors that contribute to asthma

There is still no cure for asthma, so for 22 million people in the U.S., this chronic disease continues to be a daily burden no matter where they live. But it's not just air pollution they should be worried about. Factors such as pollen, secondhand smoke – even high rates of poverty, a large uninsured population or a high number of ER visits – can be critical signs that certain cities and states are worse for families with asthma. It is especially true for people with severe asthma.

7 May 2013

Oral drops provide a safe and effective alternative for allergy sufferers

Allergy shots are commonly used to treat children with severe environmental allergies and asthma, but under-the-tongue drops may offer yet another beneficial - and stick-free - option for pediatric allergy sufferers, according to a Johns Hopkins Children's Center review of existing scientific evidence.

6 May 2013

Experts gather to lay out agenda to end childhood poverty

Pediatricians, economists, social scientists and policy experts will come together on Saturday, May 4, to address one of the greatest threats to child health - poverty.

4 May 2013

Vitamin C may decrease impact of smoking during pregnancy on childhood respiratory health

Pregnant women are advised not to smoke during pregnancy because it can harm the baby's lungs and lead to wheezing and asthma, among other problems. If a woman absolutely can't kick the habit, taking vitamin C during pregnancy may improve her newborn's lung function and prevent wheezing in the first year of life, according to a study to be presented Saturday, May 4, at the Pediatric Academic Societies (PAS) annual meeting in Washington, DC.

4 May 2013

Regeneron Pharmaceuticals expands ophthalmology portfolio

Regeneron Pharmaceuticals, Inc. today announced that it has expanded its ophthalmology portfolio by acquiring full exclusive rights to two families of novel antibodies invented at Regeneron and previously included in Regeneron's antibody collaboration with Sanofi.

3 May 2013

Study: Chalk may cause allergy and asthma symptoms in students with milk allergy

Many of today's school teachers opt for dustless chalk to keep hands and classrooms clean. But according to a study published in the May issue of Annals of Allergy, Asthma & Immunology, the scientific journal of the American College of Allergy, Asthma and Immunology (ACAAI), this choice in chalk may cause allergy and asthma symptoms in students that have a milk allergy.

3 May 2013

New official clinical practice guidelines on diagnosis, management of EIB

The American Thoracic Society has released new official clinical practice guidelines on the diagnosis and management of exercise-induced bronchoconstriction, the acute airway narrowing that occurs as a result of exercise.

2 May 2013

Polymers for pulmonary drug delivery book released by Smithers Rapra

Pulmonary drug delivery has been a rapidly expanding field, moving from the traditional propellant based metered dose inhaler delivery of small asthma drugs, to a broader landscape of new devices and novel drugs for local and systemic delivery.

30 Apr 2013

COPD-asthma overlap ‘needs greater recognition’

More attention should be given to patients who have chronic obstructive pulmonary disease and concomitant asthma, after a study showed that nearly one-fifth of patients with COPD fall into this subtype.

30 Apr 2013

Atopy’s immunologic properties change with age in asthma

The strength of interaction between atopy and elevated eosinophil levels in asthma decreases with age, a study finds.

30 Apr 2013

Children born outside U.S. have lower prevalence of allergic disease

A study by Jonathan I. Silverberg, M.D., Ph.D., M.P.H., of St. Luke's—Roosevelt Hospital Center, New York, and colleagues suggests children living the in the United States but born outside the U.S. have a lower prevalence of allergic disease that increases after residing in the United States for one decade.

30 Apr 2013

Asthma News and Research

Further Reading

Better understanding of cells' development has implications in study of inflammatory diseases

LDL cholesterol blood level declines found to have abruptly ended in 2008

More than 80% of parents, grandparents prefer hospital that does medical research about children: Study

Breo Ellipta gets FDA approval for treatment of airflow obstruction in patients with COPD

COPD patients with allergic phenotype have increased risk of lower respiratory symptoms, exacerbations

Research finds sharp rise of dementia, other neurological deaths in people under 74

Nearly 5 million asthmatics with ABPA could benefit from antifungal treatment, say researchers

Rigel reports net loss of $25.6 million in first quarter 2013

Kinase inhibitors: an interview with Jan Hoflack, CSO of Oncodesign

New report highlights factors that contribute to asthma

Oral drops provide a safe and effective alternative for allergy sufferers

Experts gather to lay out agenda to end childhood poverty

Vitamin C may decrease impact of smoking during pregnancy on childhood respiratory health

Regeneron Pharmaceuticals expands ophthalmology portfolio

Study: Chalk may cause allergy and asthma symptoms in students with milk allergy

New official clinical practice guidelines on diagnosis, management of EIB

Polymers for pulmonary drug delivery book released by Smithers Rapra

COPD-asthma overlap ‘needs greater recognition’

Atopy’s immunologic properties change with age in asthma

Children born outside U.S. have lower prevalence of allergic disease

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

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