Brain News and Research

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The human brain is the center of the human nervous system and is a highly complex organ. Enclosed in the cranium, it has the same general structure as the brains of other mammals, but is over three times as large as the brain of a typical mammal with an equivalent body size.

UNC study uses optogenetics to tweak brain wiring responsible for drug addiction behaviors

Using a combination of genetic engineering and laser technology, researchers at the University of North Carolina at Chapel Hill have manipulated brain wiring responsible for reward-seeking behaviors, such as drug addiction.

30 Jun 2011

Most cases of facial nerve paralysis in children can be treated successfully

A half-paralyzed face with a motionless, drooping side can be alarming at any age, but when it occurs in a child it can be especially devastating.

30 Jun 2011

Diagnostic delay in women with tuberous sclerosis complex increases mortality risk

Women with tuberous sclerosis complex (TSC) are often misdiagnosed because the condition, commonly recognized in early childhood when it presents with seizures, manifests differently later in life, typically with renal angiomyolipomas - a benign tumor of the kidney - and pulmonary lymphangioleiomyomatosis (LAM) - a rare lung disease that affects almost exclusively women.

30 Jun 2011

Mary Ann Liebert peer-reviewed journal highlights advances in gene therapy for neurological diseases

Novel tools and methods for delivering therapeutic genes to cells in the central nervous system hold great promise for the development of new treatments to combat incurable neurologic diseases.

30 Jun 2011

TCGA examines ovarian serous adenocarcinoma tumors from 500 patients

An analysis of genomic changes in ovarian cancer has provided the most comprehensive and integrated view of cancer genes for any cancer type to date. Ovarian serous adenocarcinoma tumors from 500 patients were examined by The Cancer Genome Atlas (TCGA) Research Network and analyses are reported in the June 30, 2011, issue of Nature.

30 Jun 2011

STSI joins JAX consortium to develop targeted cancer therapies

The Scripps Translational Science Institute (STSI) of San Diego, Calif., has joined a national consortium of research institutions headed by The Jackson Laboratory (JAX) that is building a library of primary human tumors with the goal of developing highly targeted cancer therapies.

30 Jun 2011

Protect your ears from loud noise of fireworks, trains, and concerts

The sounds of summer can be noisy. "Fireworks, trains, concerts and road construction can be harmful to your hearing. And once hearing is damaged, it cannot be repaired," said Jyoti Bhayani, certified audiologist at Gottlieb Memorial Hospital, part of Loyola University Health System.

30 Jun 2011

FDA's ODAC recommends withdrawal of Avastin approval for metastatic breast cancer

Genentech, a member of the Roche Group, announced today that, during a U.S. Food and Drug Administration (FDA) hearing, the FDA's Oncologic Drugs Advisory Committee (ODAC) recommended that the FDA withdraw its approval of Avastin in combination with paclitaxel chemotherapy for previously untreated HER2-negative metastatic breast cancer.

30 Jun 2011

Gene overexpression linked with Alzheimer's disease and Down syndrome

Chronic stress has long been linked with neurodegeneration. Scientists at USC now think they may know why.

29 Jun 2011

Patients, scientists in different corners for cancer drug fight

The drug, Avastin, will be the subject of an unusual Food and Drug Administration hearing to revisit a panel vote last July that steered many doctors away from prescribing the drug for the treatment of breast cancer.

29 Jun 2011

Humans experience the Motion Aftereffect even if the motion is brief

Scientists have come up with new insight into the brain processes that cause the following optical illusion: Focus your eyes directly on the "X" in the center of the image in this short video (http://www.youtube.com/watch?v=BXnUckHbPqM&feature=player_embedded)

29 Jun 2011

ICU nurses doubt whether clinical neurological examination can establish brain death

More than half of Sweden's intensive care nurses doubt that a clinical neurological examination can establish that a patient is brain dead. Intensive care nurses also perceive that this uncertainty can affect relatives when the question of organ donation is raised, is reveiled in a thesis from the Sahlgrenska Academy, University of Gothenburg, Sweden.

29 Jun 2011

Amorfix fiscal 2011 net loss decreases to $3,330,437

Amorfix Life Sciences, a product development company focused on diagnostics and therapeutics for misfolded protein diseases, today announced its operational and financial results for the year ended March 31, 2011, as well as financial results for the fourth quarter.

29 Jun 2011

Early musical interventions may benefit children with dyslexia having difficulties in learning to read

Children with dyslexia often find it difficult to count the number of syllables in spoken words or to determine whether words rhyme. These subtle difficulties are seen across languages with different writing systems and they indicate that the dyslexic brain has trouble processing the way that sounds in spoken language are structured.

29 Jun 2011

Emotional empathy linked to physiological responses to angry faces

Egocentric, self-centred, and insensitive to the needs of others: these social problems often arise in people with severe traumatic brain injury (TBI) and have been attributed in part to a loss of emotional empathy, the capacity to recognise and understand the emotions of other people.

29 Jun 2011

Anacor, DNDi and SCYNEXIS complete SCYX-7158 pre-clinical studies for combating sleeping sickness

Anacor Pharmaceuticals, the Drugs for Neglected Diseases initiative (DNDi), and SCYNEXIS Inc. today announced the successful completion of pre-clinical studies for the first new oral drug candidate discovered specifically to combat human African trypanosomiasis (HAT), also known as sleeping sickness.

29 Jun 2011

Rodent olfaction and the chemistry of instinct

The mechanics of instinctive behavior are mysterious. Even something as simple as the question of how a mouse can use its powerful sense of smell to detect and evade predators, including species it has never met before, has been almost totally unknown at the molecular level until now.

29 Jun 2011

GABA corrects both known causes of Type 1 diabetes

A chemical produced by the same cells that make insulin in the pancreas prevented and even reversed Type 1 diabetes in mice, researchers at St. Michael's Hospital have found.

29 Jun 2011

Genetic tools that enable cell type-specific delivery hold promise for combating incurable neurologic diseases

Novel tools and methods for delivering therapeutic genes to cells in the central nervous system hold great promise for the development of new treatments to combat incurable neurologic diseases. Five of the most exciting developments in this rapidly advancing field are presented in a series of articles in the June issue of Human Gene Therapy, a peer-reviewed journal published by Mary Ann Liebert, Inc..

29 Jun 2011

Insufficient sleep can reduce benefit of hormones released during sleep

Nearly half of all Americans reported having difficulty sleeping. The Center for Disease Control and Prevention has reported that about 35% of people surveyed in 12 states said they slept less than 7 hours a night on average.

29 Jun 2011

Brain News and Research

Further Reading

UNC study uses optogenetics to tweak brain wiring responsible for drug addiction behaviors

Most cases of facial nerve paralysis in children can be treated successfully

Diagnostic delay in women with tuberous sclerosis complex increases mortality risk

Mary Ann Liebert peer-reviewed journal highlights advances in gene therapy for neurological diseases

TCGA examines ovarian serous adenocarcinoma tumors from 500 patients

STSI joins JAX consortium to develop targeted cancer therapies

Protect your ears from loud noise of fireworks, trains, and concerts

FDA's ODAC recommends withdrawal of Avastin approval for metastatic breast cancer

Gene overexpression linked with Alzheimer's disease and Down syndrome

Patients, scientists in different corners for cancer drug fight

Humans experience the Motion Aftereffect even if the motion is brief

ICU nurses doubt whether clinical neurological examination can establish brain death

Amorfix fiscal 2011 net loss decreases to $3,330,437

Early musical interventions may benefit children with dyslexia having difficulties in learning to read

Emotional empathy linked to physiological responses to angry faces

Anacor, DNDi and SCYNEXIS complete SCYX-7158 pre-clinical studies for combating sleeping sickness

Rodent olfaction and the chemistry of instinct

GABA corrects both known causes of Type 1 diabetes

Genetic tools that enable cell type-specific delivery hold promise for combating incurable neurologic diseases

Insufficient sleep can reduce benefit of hormones released during sleep

Industry Focus eBook - Cell & Gene Therapy (1st Edition) eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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