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Study reveals how cells from patients with developmental disease differ from healthy cells

By reprogramming skin cells into nerve cells, researchers at Karolinska Institutet are creating cell models of the human brain. In a new study published in Molecular Psychiatry the researchers describe how cells from patients with the severe developmental disease lissencephaly differ from healthy cells.

19 Sep 2017

As care shifts from hospital to home, guarding against infection falls to families

Angela Cooper arrived home from work to discover her daughter’s temperature had spiked to 102 degrees — a sign that the teenager, who has cancer, had a potentially deadly bloodstream infection.

19 Sep 2017

Scientists discover markers for progressive multiple sclerosis

Scientists have uncovered two closely related cytokines -- molecules involved in cell communication and movement -- that may explain why some people develop progressive multiple sclerosis (MS), the most severe form of the disease.

18 Sep 2017

Scientists genetically engineer mice that display behavioral hallmarks of human bipolar disorder

Johns Hopkins researchers report they have genetically engineered mice that display many of the behavioral hallmarks of human bipolar disorder, and that the abnormal behaviors the rodents show can be reversed using well-established drug treatments for bipolar disorder, such as lithium.

18 Sep 2017

LSUHealthNO to examine effectiveness of novel drug designed for heart muscle regeneration

In collaboration with Novo Biosciences, Inc., LSU Health New Orleans Cardiovascular Center of Excellence will receive more $500,000 over two years to study the effectiveness of a novel drug designed to stimulate the regeneration of heart muscle and prevent the formation or scar tissue following a heart attack.

15 Sep 2017

Doctors and older patients should work together to dial back diabetes treatment, study suggests

Anyone with diabetes who takes blood sugar medication knows their doctor prescribed it to help them. After all, the long-term effects of elevated blood sugar can harm everything from the heart and kidneys to the eyes and feet.

15 Sep 2017

Penn study provides insight into how cells maintain identity during replication

Prior to cell division, chromosomes are seemingly a jumbled mess. During cell division, parent cell chromosomes and their duplicates sort themselves out by condensing, becoming thousands of times more compact than at any other time.

15 Sep 2017

Researchers discover important link between Parkinson's and prion diseases

Parkinson's disease and prion diseases are very different from each other as regards both origins and course. Nonetheless, a research group of SISSA's, headed by Professor Giuseppe Legname, has discovered an unexpected and important link between the two pathologies.

14 Sep 2017

Electrical stimulation may help restore function in paralyzed patients

Nearly 282,000 people in the U.S. live with paralysis following a spinal cord injury (SCI). A review of more than 90 studies found that electrical stimulation may help restore function in those paralyzed after SCI. The article is published in Physiology.

14 Sep 2017

New HIVMA guidelines recommend screening everyone with HIV for chronic pain

Because ongoing pain is a significant problem that affects 39 to 85 percent of people living with HIV, everyone with the infection should be assessed for chronic pain, recommend guidelines released by the HIV Medicine Association of the Infectious Diseases Society of America and published in the journal Clinical Infectious Diseases.

14 Sep 2017

Researchers find unique genetic mutation in 74-year-old man with Parkinson's disease

Mutations in the human genome may be responsible for many diseases. In the case of Parkinson's disease (PD), five locations have been the subject of recent attention. Variants of one of these locations, ACMSD (aminocarboxymuconate semialdehyde decarboxylase), may be implicated in PD, but until now, no mutations in ACMSD have been found in any PD patients.

14 Sep 2017

New shingles vaccine gets FDA panel votes

On the 13th of September 2017, a U.S. Food and Drug Administration (FDA) advisory panel has voted 11 to 0 approving a shingles vaccine for its use in adults aged 50 and over. The panel unanimously accepted the safety and efficacy of the vaccine and thus GlaxoSmithKline’s Shingrix is on its way to FDA approval.

14 Sep 2017

Novel technology holds promise for improving accuracy of type 1 diabetes tests

Researchers from the Johns Hopkins University School of Medicine, Stanford University and the University of Florida report the development of a novel antibody detection technology that holds promise for improving the accuracy of diagnostic tests for type 1 diabetes in young children and making populationwide screening practical.

13 Sep 2017

Research finds serious visual impairment among children with congenital Zika syndrome

Although one of the most serious consequences of the Zika virus (ZIKV) in infants is microcephaly, there is a broad collection of anomalies now known as congenital Zika syndrome (CZS). Some of the most serious are ophthalmologic, including macular scarring, retinal defects, low visual acuity, strabismus, and nystagmus.

13 Sep 2017

MTI awards $25,000 grant to MDI Biological Laboratory scientist for peripheral neuropathy research

The Maine Technology Institute has awarded a $25,000 seed grant to Sandra Rieger, Ph.D., of the MDI Biological Laboratory to study peripheral neuropathy, a condition that causes pain, tingling and numbness in the hands and feet and affects an estimated 20 to 40 million Americans.

13 Sep 2017

Researchers develop model to explore hard-to-study mutations in human genome

A team of researchers led by a bioinformatician at the University of California San Diego has developed a method to help determine whether certain hard-to-study mutations in the human genome, called short tandem repeats or microsatellites, are likely to be involved in harmful conditions.

11 Sep 2017

A rare dementia gene runs in the family, but he’s fine — so far

John Janda knows he takes after his mother. At 68, the graying building contractor is sentimental, just as she was. He smiles indulgently as he shows off photos of his 9-month-old grandson; he tears up at the memory of losing his dad in a construction accident more than 40 years ago.

11 Sep 2017

Nerve News and Research

Study reveals how cells from patients with developmental disease differ from healthy cells

As care shifts from hospital to home, guarding against infection falls to families

Scientists discover markers for progressive multiple sclerosis

Scientists genetically engineer mice that display behavioral hallmarks of human bipolar disorder

LSUHealthNO to examine effectiveness of novel drug designed for heart muscle regeneration

Doctors and older patients should work together to dial back diabetes treatment, study suggests

Penn study provides insight into how cells maintain identity during replication

Researchers discover important link between Parkinson's and prion diseases

Electrical stimulation may help restore function in paralyzed patients

New HIVMA guidelines recommend screening everyone with HIV for chronic pain

Researchers find unique genetic mutation in 74-year-old man with Parkinson's disease

New shingles vaccine gets FDA panel votes

Novel technology holds promise for improving accuracy of type 1 diabetes tests

Research finds serious visual impairment among children with congenital Zika syndrome

MTI awards $25,000 grant to MDI Biological Laboratory scientist for peripheral neuropathy research

Researchers develop model to explore hard-to-study mutations in human genome

A rare dementia gene runs in the family, but he’s fine — so far

Retinal imaging may help doctors confirm or rule out frontotemporal degeneration

Neuroscientists discover new signaling pathway that could be good drug target to fight chronic pain

Cold Spring Harbor Laboratory Press releases new book on Cell Polarity

The impact of vibration on microscopy

How Omics Technologies Are Transforming Biological Research and Drug Discovery

How microplastics and bacteria interact to drive antibiotic resistance

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