Diagnostic News and Research

RSS

AI beats primary care doctors in simulated diagnosis study using images and ECGs

Multi-modal AMIE used state-aware reasoning to interpret patient history alongside skin photos, ECGs, and clinical documents during simulated telehealth consultations. In a blinded exploratory OSCE-style study, AMIE outperformed primary care physicians across most diagnostic, communication, empathy, and multimodal reasoning measures, but still requires real-world clinical validation.

17 May 2026

New guidelines for identifying and treating high-risk IEC-HS patients

Chimeric antigen receptor T-cell (CAR-T) therapy has revolutionized the treatment of hematologic malignancies, offering durable responses for patients with otherwise refractory disease. However, its clinical success is accompanied by a spectrum of immune-related toxicities, which remain a major challenge in practice.

15 May 2026

New FUSILLI tool improves gene fusion detection in pediatric leukemia

Researchers have introduced a novel diagnostics method that can more sensitively detect gene fusions in B-cell acute lymphoblastic leukemia (B-ALL), the most common type of pediatric cancer, compared to other publicly available fusion detection algorithms.

15 May 2026

Identifying the methodology gap that prevents treatment of infection-triggered chronic diseases

Thousands of Americans develop chronic persistent symptoms-such as fatigue, cognitive difficulties ("brain fog"), and other debilitating issues-each year following acute infections from Lyme disease, COVID-19, and other pathogens. Efforts to identify causes and produce treatments have failed. However, 16 leading researchers think they know part of the problem: study design.

14 May 2026

Scientists develop a superior diagnostic tool to spot hidden gene fusions in pediatric cancer

Researchers have introduced a novel diagnostic method that can more sensitively detect gene fusions in B-cell acute lymphoblastic leukemia (B-ALL), the most common type of pediatric cancer, compared to other publicly available fusion detection algorithms.

14 May 2026

Smart technology meets wound care to combat dangerous diabetic ulcers

"Diabetic ulcers," which occur in patients with diabetes, are dangerous complications that can lead to amputation if the treatment window is missed. A joint research team has developed a "smart dressing patch" that can monitor wound conditions in real time.

14 May 2026

New non invasive way to diagnose childhood epilepsy through blood sugar patterns

A study published in Engineering has demonstrated that the N-glycome of serum-derived extracellular vesicles (EVs) can serve as a non-invasive biosignature for the diagnosis and classification of childhood epilepsy, offering a new tool for precision and longitudinal monitoring in clinical settings.

14 May 2026

Gene panel predicts chemotherapy response in triple-negative breast cancer

Researchers at The University of Texas MD Anderson Cancer Center have characterized cancer cell-specific features in the tumor microenvironment (TME) of early-stage triple-negative breast cancer (TNBC) tissues, identifying specific macrophage subtypes associated with chemotherapy response.

13 May 2026

New trial aims to improve ATTR-CM diagnosis in heart failure

Transthyretin amyloid cardiomyopathy (ATTR-CM) is an increasingly recognized yet frequently underdiagnosed cause of heart failure, particularly among older adults.

13 May 2026

Why experts say PCOS needs a new name

A Lancet Health Policy paper reports an international consensus process that selected polyendocrine metabolic ovarian syndrome (PMOS) as the new name for polycystic ovary syndrome (PCOS). The change aims to shift the focus away from ovarian cysts and better reflect the condition’s endocrine, metabolic, and ovarian features.

13 May 2026

Gut microbes may reveal why diabetes raises heart disease risk

Integrated gut microbiome and plasma metabolomics profiling identified distinct microbial and metabolic signatures in people with T2DM and T2DM-CAD. In a small exploratory cohort, Bacteroides sp._CAG_875 and 12-ketoLCA emerged as candidate markers that may help distinguish diabetic patients with coronary complications, pending larger validation.

13 May 2026

AI-powered handheld microscope may improve early cancer detection

Researchers at Rice University and The University of Texas MD Anderson Cancer Center have developed a compact, artificial intelligence-powered imaging device that could transform how clinicians detect cancer.

12 May 2026

Home-based assessments may detect early mobility risks

Predicting whether a healthy 45-year-old will struggle to climb stairs or walk a decade later has long been a challenge for geriatric medicine.

12 May 2026

Dual-pathway protein degradation approach could improve cancer treatment

Targeted protein degradation has become one of the most promising strategies in modern drug discovery, enabling scientists to eliminate disease-causing proteins instead of merely blocking them.

12 May 2026

Interactive AI model improves explainable lung cancer diagnosis from CT scans

Lung cancer remains one of the leading causes of cancer-related deaths worldwide, making early and accurate diagnosis essential for improving patient outcomes.

12 May 2026

Could GLP-1 drugs help breast cancer patients live longer?

A large retrospective cohort study of adult female breast cancer patients found that GLP-1 receptor agonist use was associated with better all-cause survival and recurrence-free survival in patients with obesity or type 2 diabetes. The strongest associations were seen versus non-use in obesity and versus insulin or metformin in type 2 diabetes, while comparisons with SGLT2 inhibitors were less consistent and require further study.

12 May 2026

Why is the US falling behind other high-income nations on survival?

A JAMA Network Open study found that the US recorded 12.7 million excess deaths compared with 17 peer high-income countries between 1999 and 2022. Circulatory and metabolic diseases drove much of the burden, while drug poisonings, alcohol-related deaths, and suicide sharply widened the gap among younger Americans.

12 May 2026

BGI Genomics joins HGP2 Rare Disease Alliance to close rare disease care gap in Asia-Pacific

The HGP2 RaDiAnce-APAC initiative enhances rare disease diagnosis and genomic medicine, fostering collaboration for improved health in the Asia-Pacific region.

From BGI Genomics 12 May 2026

New AI chip identifies meibomian gland dysfunction within milliseconds

A research team from Peking Union Medical College Hospital and Tsinghua University has developed a compact optical AI chip that can identify meibomian gland dysfunction (MGD)-a major cause of dry eye disease-with more than 96% accuracy by analyzing the tissue's spectral signatures.

11 May 2026

Physician mothers return to work sooner than many Canadian parents, study finds

Ontario physicians increased their workload in the first two trimesters of pregnancy, suggesting many may frontload clinical work before parental leave. Parental leave varied widely by specialty, with surgeons returning earliest and psychiatrists returning latest, highlighting persistent inequities in how medical practice supports childbearing physicians.

11 May 2026