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Single-cell genomic sequencing identifies a subpopulation of human dopamine neurons that degenerates in Parkinson’s disease

Researchers developed a novel protocol to examine dopamine (DA) neurons extracted from Parkinson’s disease (PD) patients using single-cell genomic sequencing.

9 May 2022

Newly-discovered mechanism may help prevent the build-up toxic proteins in dementia

It's often said that a little stress can be good for you. Now scientists have shown that the same may be true for cells, uncovering a newly-discovered mechanism that might help prevent the build-up of tangles of proteins commonly seen in dementia.

6 May 2022

One step solvothermal synthesis of pure red emissive carbon dots from citric acid and urea in formic acid

Carbon dots (CDs) are a kind of zero-dimensional carbonaceous nanomaterial. Due to their ultra-small size (usually less than 10 nm), simple synthesis, low toxicity, well-documented biocompatibility, and outstanding luminescent properties, CDs have attracted wild applications, particularly in bioimaging and biomedical fields.

3 May 2022

Multifunctional YHM shows promise for diagnosis and treatment of orthotopic glioma

Glioma is an intracranial malignant tumor that still poses a major clinical challenge due to its highly invasive nature, low cure rate, and high mortality rate.

3 May 2022

New technology to make temporary genetic modifications tested in mosquitoes

Texas A&M AgriLife Research scientists have tested a technology to make temporary genetic modifications in mosquitoes. The modifications self-delete over time.

3 May 2022

Study reports an orally available SARS-CoV-2 Mpro inhibitor with potent in vivo antiviral activity

Researchers examined the efficiency of the main protease (Mpro) inhibitor against SARS-CoV-2.

29 Apr 2022

New insights into how NANOG protein facilitates the activation of human cell pluripotency

There are cells in the body known as pluripotent stem cells that are yet to specialize in a particular biological function.

28 Apr 2022

Evaluating nano alum as a substitute for conventional alum-based vaccine adjuvant

Researchers evaluated the performance and safety of nano alum adjuvant as next-generation coronavirus disease 2019 (COVID-19) vaccine antigens.

28 Apr 2022

Green tea catechin as pan-coronavirus attachment inhibitor

In a recent study posted to the Research Square* preprint server, researchers assessed the impact of green tea catechin epigallocatechin gallate (EGCG) on severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).

27 Apr 2022

Free fatty acid-binding pocket found to be preserved across spike proteins of beta coronaviruses

Researchers assessed the binding pocket of linoleic acid, an essential free-fatty acid in the receptor-binding domains of the spike protein of beta-coronaviruses.

26 Apr 2022

Evidence of increased intrinsic cleavability of SARS-CoV-2 Omicron spike protein by host cell furin

Researchers conducted an in vitro analysis to assess the host cell furin-mediated cleavability of the spike protein of the SARS-CoV-2 Omicron (B.1.529) variant.

26 Apr 2022

Nanobody effectively neutralizes pseudotyped ancestral SARS-CoV-2 and Omicron spike proteins

Researchers identified a nanobody inhibiting SARS-CoV-2 variants.

26 Apr 2022

Quantum dot biomimetic for SARS-CoV-2 examines neurovascular dysregulation related to brain inflammation

Researchers developed SARS-CoV-2 virus-like nanoparticles with a quantum dots core.

26 Apr 2022

Exploring Populations of B and T Cells in Lymph Nodes of Patients Diagnosed with COVID-19 via Microscopy and Image Analysis

My work is focused on looking at the dynamics of B/T cell populations within lymph nodes from patients that had recovered from COVID-19. My role in this research was developing and implementing microscopy image analysis techniques using methods and instrumentation in part supplied by TissueGnostics.

From TissueGnostics 26 Apr 2022

A novel mouse model to test SARS-CoV-2 viral infection

In a recent study posted to the Research Square* preprint server, researchers developed a novel mouse model for testing infection by severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2).

26 Apr 2022

Scientists win $2.85 million grant to use novel technology for studying babies with hydrocephalus

A five-year, $2.85 million grant to use novel technology to study babies with hydrocephalus has been awarded to a team of UTHealth Houston researchers by the National Institute of Neurological Disorders and Stroke, part of the National Institutes of Health.

25 Apr 2022

Fluorescence News and Research

Single-cell genomic sequencing identifies a subpopulation of human dopamine neurons that degenerates in Parkinson’s disease

Newly-discovered mechanism may help prevent the build-up toxic proteins in dementia

One step solvothermal synthesis of pure red emissive carbon dots from citric acid and urea in formic acid

Multifunctional YHM shows promise for diagnosis and treatment of orthotopic glioma

New technology to make temporary genetic modifications tested in mosquitoes

Study reports an orally available SARS-CoV-2 Mpro inhibitor with potent in vivo antiviral activity

New insights into how NANOG protein facilitates the activation of human cell pluripotency

Evaluating nano alum as a substitute for conventional alum-based vaccine adjuvant

Green tea catechin as pan-coronavirus attachment inhibitor

Free fatty acid-binding pocket found to be preserved across spike proteins of beta coronaviruses

Evidence of increased intrinsic cleavability of SARS-CoV-2 Omicron spike protein by host cell furin

Nanobody effectively neutralizes pseudotyped ancestral SARS-CoV-2 and Omicron spike proteins

Quantum dot biomimetic for SARS-CoV-2 examines neurovascular dysregulation related to brain inflammation

Exploring Populations of B and T Cells in Lymph Nodes of Patients Diagnosed with COVID-19 via Microscopy and Image Analysis

A novel mouse model to test SARS-CoV-2 viral infection

Scientists win $2.85 million grant to use novel technology for studying babies with hydrocephalus

ST6Gal-I–mediated sialylation of the EGFR modulates cell mechanics and enhances cancer invasion

New photo-responsive nanomedicine for light-controlled colorectal cancer therapy

Study evaluates the ocular tropism and the possible ocular transmission of SARS-CoV-2 in animal models

New study pinpoints how immune checkpoint protein LAG3 modulates T cell activity

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