Immune System News and Research

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Gene deletion exposes hidden colon cancer cells to immunotherapy attack

A study from the University of Calgary shows that removing a single gene makes colon cancer cells a target for immunotherapy - a fundamental breakthrough.

18 Jun 2026

Breast milk nutrient boosts long-term immune system development

Trans-vaccenic acid (TVA), the most abundant trans fatty acid found in human breast milk, helps boost immune system development and has long-lasting effects on immune system health in mice, according to a new study by researchers from the University of Chicago.

18 Jun 2026

Indiana University researchers investigate immune cell aging in Parkinson's disease

A new cutting-edge research team, led by Indiana University School of Medicine scientists and interdisciplinary experts from multiple universities, will investigate the role of immune cell aging on Parkinson's disease risk and progression.

18 Jun 2026

New mRNA vaccine shrinks neuroblastoma tumors in preclinical study

A new study from RCSI University of Medicine and Health Sciences demonstrates a novel approach in anticancer vaccine development. Results present the first preclinical evidence to show the efficacy of an mRNA vaccine in targeting neuroblastoma, the deadliest childhood cancer.

18 Jun 2026

Mental health problems common in encephalitis survivors, study finds

A major new study has found that mental health and behavioral changes such as depression, anxiety, and emotional instability are common in people who survive encephalitis - inflammation of the brain that can be caused by infection or autoimmune disease.

18 Jun 2026

Cerebral organoid model offers insights into the mechanisms of Ebola virus persistence

Following infection, Ebola virus can survive unnoticed in the human body for months or even years, hiding in areas with little immune surveillance like the central nervous system.

17 Jun 2026

Preoperative radiation boosts immunotherapy response in brain metastases

A new study led by researchers at The University of Texas MD Anderson Cancer Center demonstrated that pre-operative radiation therapy for brain metastases not only targets tumor cells directly but also can activate immune pathways that can make tumors more receptive to immunotherapy.

17 Jun 2026

First human trial targets aging immune cells for healthier immunity

A first-in-human clinical trial of an immune rejuvenation therapy designed to restore the function of worn-out T cells is expected to begin later this year, building on research led by UCL scientists into the mechanisms of immune aging.

17 Jun 2026

WashU study identifies shared target for a new diarrhea vaccine

The bacteria enterotoxigenic E. coli and Shigella together cause hundreds of millions of infections each year and are among the leading causes of diarrheal death, especially in children.

17 Jun 2026

Targeting immune cells could improve colorectal cancer treatments

Researchers at the Medical University of Vienna have described a mechanism in metastatic colorectal cancer that has received little attention to date: a key target of existing therapies, the so-called epidermal growth factor receptor (EGFR), is likely to affect more than just the cancer cells themselves.

17 Jun 2026

New study reveals cause of chronic inflammation with age

A new study led by researchers at The University of Texas MD Anderson Cancer Center has uncovered a previously unknown connection between nucleic acid structures called R-loops and age-related inflammation – or inflammaging – that could herald new intervention options for chronic inflammation and the subsequent health conditions.

16 Jun 2026

Heart tissue repair drug may also help repair and regenerate damaged kidney tissues

A drug previously developed at UCLA to help heart tissue repair itself after a heart attack might also help kidney tissue repair and regenerate, researchers have found.

16 Jun 2026

FutureNeuro launches proteomics study to personalize psychosis treatment

FutureNeuro, the Research Ireland Centre for Translational Brain Science hosted by RCSI University of Medicine and Health Sciences, has launched a new proteomics study aimed at identifying biological markers that could support more personalized treatment for people experiencing first‑episode psychosis.

16 Jun 2026

Maternal weight shifts microbiota signaling in the fetal environment

A study conducted at the University of Oulu and Oulu University Hospital suggests that factors related to maternal weight are reflected in signaling particles produced by the maternal microbiota not only in the gut but also in amniotic fluid.

15 Jun 2026

Neutrophils reduce the effectiveness of cancer immunotherapy in mice

A type of white blood cell in the immune system, known as neutrophils, can make cancer immunotherapy less effective. This is shown in a new study from Karolinska Institutet published in the journal Immunity.

15 Jun 2026

Tumor microenvironment drives drug resistance in lung cancer subtypes

A study by the University of Barcelona has discovered why the two main types of lung cancer — adenocarcinoma of the lung and squamous cell carcinoma — respond differently to anti-angiogenic therapy, that is, drugs that block the formation of new blood vessels that tumors need in order to grow.

15 Jun 2026

Dual-target CAR T therapy triggers broad immune response in brain cancer

Dual-target CAR T cell therapy for recurrent glioblastoma (GBM), delivered directly into the cerebrospinal fluid (CSF), triggers a broad immune response, with natural killer (NK) cell activation linked to better patient outcomes and longer overall survival.

15 Jun 2026

New mRNA flu vaccine offers broader protection against influenza strains

A new study led by researchers at Washington University School of Medicine in St. Louis has found that an investigational mRNA influenza vaccine helps the immune system recognize a wider range of influenza viruses than today's standard flu shot, offering stronger and potentially longer-lasting protection.

15 Jun 2026

Mutation in OTULIN gene causes rare childhood skin disease

An international team of researchers has identified a genetic cause for a rare inflammatory skin condition.

15 Jun 2026

Blood-based indicator assesses organ age to predict disease risk

The candles on your birthday cake don't tell the whole story. As anyone who ever attended a high-school reunion can tell you, some people age faster than others.

15 Jun 2026