Antibody News and Research

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An antibody is a blood protein that is produced in response to and counteracts an antigen. Antibodies are produced in response to disease and help the body fight against the particular disease. In this way, antibodies help the body develop an immunity to disease.

Small portion of COVID-19 patients infectious long-term

In late December 2019, a novel pneumonia-like lung infection was reported in the Chinese province of Hubei. This, in turn, led to the ongoing coronavirus disease-19 (COVID-19) pandemic. COVID-19 is caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), which is closely related to SARS (Severe Acute Respiratory Syndrome) and MERS (the Middle East Respiratory Syndrome Coronavirus).

13 Oct 2021

New study finds SARS-CoV-2 causes retinal infection

Can coronavirus disease 2019 (COVID-19) affect the eye? New research suggests the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) can enter the eye and infect photoreceptor and retinal ganglion cells. In addition, SARS-CoV-2 infection increases the expression of several inflammatory genes, including the cytokine interleukin 33 (IL33), which is linked to COVID-19 disease and retinal degeneration.

13 Oct 2021

COVID-19 vaccination induces transient increase in cellular and antibody responses to S1 antigenic sequence

Scientists have characterized T-cell, B-cell, and IgG responses to S antigenic sequences to evaluate vaccine effectiveness.

13 Oct 2021

Comparing lateral flow testing with RT-PCR to detect SARS-CoV-2

Lateral flow devices (LFDs) are point-of-care tests that require significantly more time to develop than RT-PCR assays but can be used locally with minimal to no training, some of which can provide results in as little as 30 minutes. However, there have been some worries about the sensitivity of such kits. As a result, researchers from Micropathology Ltd have been comparing the two methods.

12 Oct 2021

How long does natural immunity produced by SARS-CoV-2 infection last?

A new study posted to the bioRxiv* preprint server followed the adaptive immune response in convalescent patients from Swedish and Italian cohorts—which had earlier shown long-lasting adaptive immune responses to the G614 strain—for 15 months. Here, specific antibody levels and neutralizing antibody titers were tested against variants of concern (VOCs).

12 Oct 2021

New modeling highlights the role of socio-economic status in Covid-19 transmission in Kenya

Combining data on antibody prevalence, PCR test results, genomic surveillance and population mobility from smartphones has allowed infectious disease modelers to explain the evolution of the first three Covid-19 waves that have affected Kenya since the start of the pandemic.

12 Oct 2021

Vaccinated children induced significantly higher antibody titers than naturally SARS-CoV-2 infected children

A recent preprint discusses the antibody response to the nucleic acid vaccines against SARS-CoV-2 when administered to children aged 7-11 years.

12 Oct 2021

COVID-19 vaccination elicits broader antibody response to SARS-CoV-2 spike than infection

A recent study demonstrates that antibodies generated in response to mRNA-based COVID-19 vaccination target more epitopes across the spike protein.

11 Oct 2021

SARS-CoV-2 immune responses in nursing home residents after full vaccination with Pfizer-BioNTech COVID-19 vaccine

A new study assesses antibody and functional T-cell responses at 6 months after complete vaccination with the Pfizer-BioNTech vaccine.

11 Oct 2021

Antibody validation and rapid peptide mapping technology

In this interview, News-Medical speaks to Bin Ma, President of Rapid Novor, about antibody validation and rapid peptide mapping technology.

From Rapid Novor Inc 11 Oct 2021

Delta variant exhibits immune evasion, enhanced cell entry, and augmented syncytium formation

Researchers addressed the question of using reporter particles pseudotyped with the S protein of SARS-CoV-2, which are suitable tools to examine SARS-CoV-2 neutralization antibodies.

11 Oct 2021

Vaccine-induced memory B cells can recognize SARS-CoV-2 variants

Researchers have been investigating the effect that memory B cells produced in individuals who have received an mRNA vaccine have against SARS-CoV-2 variants.

11 Oct 2021

Sero-epidemiological insights into pathways to COVID-19 immunity

A new study posted to the medRxiv* server attempts to utilize serology as a tool to identify disparities in infection rates and vaccination coverage.

10 Oct 2021

Research finds different antibody responses following COVID vaccination and natural infection

A new study published in the journal Nature attempted to investigate memory B cell evolution 5 months after vaccination with mRNA vaccines such as Moderna (mRNA-1273) or Pfizer-BioNTech (BNT162b2) in SARS-CoV-2 naïve individuals. The study explored various aspects of memory B cell antibody response like neutralizing response, affinity, epitope targeting, and neutralizing breadth.

10 Oct 2021

Antibody News and Research

Further Reading

Small portion of COVID-19 patients infectious long-term

New study finds SARS-CoV-2 causes retinal infection

COVID-19 vaccination induces transient increase in cellular and antibody responses to S1 antigenic sequence

Comparing lateral flow testing with RT-PCR to detect SARS-CoV-2

How long does natural immunity produced by SARS-CoV-2 infection last?

New modeling highlights the role of socio-economic status in Covid-19 transmission in Kenya

Vaccinated children induced significantly higher antibody titers than naturally SARS-CoV-2 infected children

COVID-19 vaccination elicits broader antibody response to SARS-CoV-2 spike than infection

SARS-CoV-2 immune responses in nursing home residents after full vaccination with Pfizer-BioNTech COVID-19 vaccine

Antibody validation and rapid peptide mapping technology

Delta variant exhibits immune evasion, enhanced cell entry, and augmented syncytium formation

Vaccine-induced memory B cells can recognize SARS-CoV-2 variants

Sero-epidemiological insights into pathways to COVID-19 immunity

Research finds different antibody responses following COVID vaccination and natural infection

Accumulation of SARS-CoV-2 mutations reduces sensitivity to neutralizing antibodies

Inactivated polio vaccine induces antibodies that block SARS-CoV-2 RNA synthesis

Phase I clinical trial of two Cuban recombinant protein COVID-19 vaccines

Powerful neutralizing antibody against SARS-CoV-2 variants of concern

Characterization of circulating neutrophils from hospitalized COVID-19 patients

Study supports efficacy and safety of lung-selective nanotherapy against SARS-CoV-2 infection

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