Efficacy News and Research

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Placebo in addition to methadone shown to be feasible treatment for opioid use disorder

There were more than 100,000 reported deaths from opioid overdoses in 2021, according to the Centers for Disease Control and Prevention.

12 Apr 2023

Simple blood test will help neurologists to make a definitive and rapid diagnosis of ALS

ALS is a rare paralytic neurological disease that can impact people in the prime of life. Delays in receiving a definitive diagnosis can be devastating for patients who typically survive only 2–5 years post-diagnosis.

12 Apr 2023

AI can identify subtle language and audio changes in patients at early stages of Alzheimer's

New technologies that can capture subtle changes in a patient's voice may help physicians diagnose cognitive impairment and Alzheimer's disease before symptoms begin to show, according to a UT Southwestern Medical Center researcher who led a study published in the Alzheimer's Association publication Diagnosis, Assessment & Disease Monitoring.

12 Apr 2023

The identification of vaccinee-derived antibodies with broad-spectrum Omicron neutralization activity

Reported the identification of a panel of vaccinee-derived antibodies with broad-spectrum neutralization activity.

12 Apr 2023

Understanding the dynamics of airborne transmission in enclosed spaces: implications for disease control in indoor superspreading events

Researchers investigated the dynamics of airborne diseases in enclosed spaces.

12 Apr 2023

Conflicting recommendations on COVID-19 vaccination for pregnant and breastfeeding individuals in Canada

In a recent study published in the journal SSM – Qualitative Research in Health, researchers in Canada examined expert discourses about coronavirus disease 2019 (COVID-19) vaccination in pregnancy.

12 Apr 2023

Optimized genome-editing method opens the door to more effective treatment of genetic diseases

CRISPR-Cas9 is widely used to edit the genome by studying genes of interest and modifying disease-associated genes.

11 Apr 2023

Digitalization is increasing the prevalence of anxiety and depression worldwide

Researchers evaluate the impact of digitalization on a societal level by using a linguistic big-data approach.

11 Apr 2023

University Hospital Bonn coordinates eWHORM project to combat worm infections in sub-Saharan Africa

African and European partners join forces to enable the World Health Organisation's (WHO) "Road Map for Neglected Tropical Diseases" (NTDs) and reduce the burden of disease associated with worm infections.

11 Apr 2023

Daily statin medication could improve cardiovascular outcomes in people with HIV

A National Institutes of Health clinical trial was stopped early because a daily statin medication was found to reduce the increased risk of cardiovascular disease among people living with HIV in the first large-scale clinical study to test a primary cardiovascular prevention strategy in this population.

11 Apr 2023

Personalized drug therapy for hypertension may provide maximum benefit

Patients treated with blood pressure-lowering drugs can experience much greater improvements from a change of medication than from doubling the dose of their current medication.

11 Apr 2023

How do dietary patterns, food and nutritional supplements affect outcomes in mild cognitive impairment?

Researchers reviewed the evidence on the effects of dietary patterns, nutritional supplements, and foods on cognitive decline.

11 Apr 2023

Study finds human surfactant protein A can inhibit SARS-CoV-2 infectivity

Researchers assess the efficacy of the human surfactant protein A against SARS-CoV-2 infectivity.

10 Apr 2023

U-M awarded a new seven-year, $71M Clinical and Translational Science Award

Traditionally, the timeline for translating research into effective therapies for disease has been long. On average, it takes more than 10 years to bring a potential medication to market, and most drugs and other interventions that reach clinical trials fail to produce any benefit for patients.

10 Apr 2023

Antepartum vs. postpartum vaccination: which provides the most protection against SARS-CoV-2 in breastfed infants?

Researchers evaluated the efficacy of transplacental transfer of antibodies against SARS-CoV-2 to infants.

10 Apr 2023

Immune checkpoint inhibitor treatment is facilitated by dietary tryptophan metabolite synthesized by Lactobacillus reuteri

Researchers highlight how dietary tryptophan metabolite released by intratumoral Lactobacillus reuteri facilitates immune checkpoint inhibitor treatment.

10 Apr 2023

COVID mRNA vaccines fall short in eliciting lung resident memory T cells compared to natural infection

Pieren, D. K. J., Kuguel, S. G., Rosado, J., Robles, A. G., Rey-Cano, J., Mancebo, C., Esperalba, J., Falcó, V., Buzón, M. J., & Genescà, M. (2023). Limited induction of polyfunctional lung-resident memory T cells against SARS-CoV-2 by mRNA vaccination compared to infection. Nature Communications, 14(1). https://doi.org/10.1038/s41467-023-37559-w, https://www.nature.com/articles/s41467-023-37559-w

10 Apr 2023

Air pollution lowers COVID-19 vaccine immune response

In a recent study published in the journal Environmental Health Perspectives, researchers performed a population-level cohort study in Catalonia, Spain, to evaluate the association between exposure to air pollution for a prolonged duration and coronavirus disease 2019 (COVID-19) vaccine-induced antibody response.

9 Apr 2023

Study opens new possibilities of tailoring radiopharmaceutical treatment to neuroendocrine cancer patients

A simple blood draw can provide physicians with valuable information that can determine if peptide receptor radionuclide therapy (PRRT) is likely to be effective in a patient with neuroendocrine cancer.

7 Apr 2023

The association between omega-3 polyunsaturated fatty acid intake and reduced risk of Alzheimer's disease

Researchers evaluated the association between omega-3 polyunsaturated fatty acids intake, cognitive decay, and dementia.

7 Apr 2023

Efficacy News and Research

Placebo in addition to methadone shown to be feasible treatment for opioid use disorder

Simple blood test will help neurologists to make a definitive and rapid diagnosis of ALS

AI can identify subtle language and audio changes in patients at early stages of Alzheimer's

The identification of vaccinee-derived antibodies with broad-spectrum Omicron neutralization activity

Understanding the dynamics of airborne transmission in enclosed spaces: implications for disease control in indoor superspreading events

Conflicting recommendations on COVID-19 vaccination for pregnant and breastfeeding individuals in Canada

Optimized genome-editing method opens the door to more effective treatment of genetic diseases

Digitalization is increasing the prevalence of anxiety and depression worldwide

University Hospital Bonn coordinates eWHORM project to combat worm infections in sub-Saharan Africa

Daily statin medication could improve cardiovascular outcomes in people with HIV

Personalized drug therapy for hypertension may provide maximum benefit

How do dietary patterns, food and nutritional supplements affect outcomes in mild cognitive impairment?

Study finds human surfactant protein A can inhibit SARS-CoV-2 infectivity

U-M awarded a new seven-year, $71M Clinical and Translational Science Award

Antepartum vs. postpartum vaccination: which provides the most protection against SARS-CoV-2 in breastfed infants?

Immune checkpoint inhibitor treatment is facilitated by dietary tryptophan metabolite synthesized by Lactobacillus reuteri

COVID mRNA vaccines fall short in eliciting lung resident memory T cells compared to natural infection

Air pollution lowers COVID-19 vaccine immune response

Study opens new possibilities of tailoring radiopharmaceutical treatment to neuroendocrine cancer patients

The association between omega-3 polyunsaturated fatty acid intake and reduced risk of Alzheimer's disease

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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