Disability News and Research

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Rethinking kindergarten reading screenings for better outcomes

In most states, schools are required to screen students as they enter kindergarten - a process that is meant to identify students who may need extra help learning to read. However, a new study by MIT researchers suggests that these screenings may not be working as intended in all schools.

29 Oct 2025

Harnessing bioinformatics to fast-track the discovery of spinal cord injury drug

Spinal cord injury (SCI) remains a major unmet medical challenge, often resulting in permanent paralysis and disability with no effective treatments.

29 Oct 2025

Specialized type of cardiac fibroblasts can actively worsen heart failure

Heart failure (HF) is one of the leading causes of death and disability worldwide, affecting millions of people and placing an enormous burden on healthcare systems.

29 Oct 2025

Mount Sinai receives $4.5 million grant to investigate neural mechanisms underlying bipolar disorder

The Icahn School of Medicine at Mount Sinai is pleased to announce it has received a three-year, $4.5 million grant from BD2: Breakthrough Discoveries for thriving with Bipolar Disorder to investigate the neural mechanisms underlying bipolar disorder and pioneer novel neuromodulation-based treatment strategies.

28 Oct 2025

Obesity’s health risks shift with age and sex, new genetic study reveals

Using a new time-resolved Mendelian randomization approach in over 360,000 UK Biobank participants, Karlsson et al. revealed that the causal impact of obesity changes across life, with distinct age- and sex-specific risk patterns for diabetes, heart disease, atrial fibrillation, and osteoarthritis.

27 Oct 2025

Genetic analysis of blood sample could offer a non-invasive way for early Parkinson’s diagnosis

The genetic analysis of a blood sample could become a tool for the early diagnosis of Parkinson's disease, according to an exploratory study led by researchers from the Miguel Hernández University of Elche (UMH).

27 Oct 2025

First multiple sclerosis patient in the UK receives CAR T cell therapy in groundbreaking trial

A multiple sclerosis (MS) patient in the UK was the first to receive CAR T cell therapy, invented by UCL researchers, in a clinical trial testing whether this personalized treatment can slow or even halt the progression of the disease.

24 Oct 2025

Boston Children's Hospital secures $8.1M for spastic paraplegia research

Boston Children's Hospital has received $8.1M in NIH funding to support and expand the Spastic Paraplegia Centers of Excellence Research Network (SP-CERN). Darius Ebrahimi-Fakhari, M.D., Ph.D., Director of the Movement Disorders Program at Boston Children's, and his team will lead this multi-center effort.

24 Oct 2025

Football injuries, not injections, explain why retired players face higher osteoarthritis risk

Retired UK male footballers face a markedly higher risk of foot and ankle osteoarthritis (OA), primarily due to prior injuries sustained during their careers. While corticosteroid injections were linked with OA, this association likely reflects treatment for injury rather than a direct cause.

23 Oct 2025

PAHO celebrates over three decades without polio in the Americas

World Polio Day (October 24), the Pan American Health Organization (PAHO) celebrates over three decades without wild poliovirus cases in the Americas.

23 Oct 2025

Foot or ankle injuries in professional football players may increase risk of osteoarthritis

A new paper in Rheumatology, published by Oxford University Press, finds that retired UK male professional football players who reported foot or ankle injuries during their careers were more likely to develop osteoarthritis in retirement.

22 Oct 2025

Nuclear binding protein identified as key contributor to trisomy 21-related CHDs

Three copies of chromosome 21 causes Down syndrome (DS), and roughly half of children born each year in the United States with DS-approximately 2,600-also have congenital heart defects (CHDs).

22 Oct 2025

Repeated ketamine infusions offer no extra benefit for people hospitalized with depression

Findings from a randomized and blinded clinical trial investigating repeated ketamine infusions for treating depression have revealed no extra benefit for ketamine when added onto standard care for people admitted to hospital for depression.

22 Oct 2025

Genetic inflammatory signature defines depression subtypes and treatment response

Researchers led by Prof. Alessandro Serretti at Kore University of Enna have identified a genetic inflammatory signature that defines specific depression subtypes and influences how patients respond to antidepressant medications, according to new peer-reviewed research published today in Genomic Psychiatry.

21 Oct 2025

Disability News and Research

Rethinking kindergarten reading screenings for better outcomes

Harnessing bioinformatics to fast-track the discovery of spinal cord injury drug

Specialized type of cardiac fibroblasts can actively worsen heart failure

Mount Sinai receives $4.5 million grant to investigate neural mechanisms underlying bipolar disorder

Obesity’s health risks shift with age and sex, new genetic study reveals

Genetic analysis of blood sample could offer a non-invasive way for early Parkinson’s diagnosis

First multiple sclerosis patient in the UK receives CAR T cell therapy in groundbreaking trial

Boston Children's Hospital secures $8.1M for spastic paraplegia research

Football injuries, not injections, explain why retired players face higher osteoarthritis risk

PAHO celebrates over three decades without polio in the Americas

Foot or ankle injuries in professional football players may increase risk of osteoarthritis

Nuclear binding protein identified as key contributor to trisomy 21-related CHDs

Repeated ketamine infusions offer no extra benefit for people hospitalized with depression

Genetic inflammatory signature defines depression subtypes and treatment response

Private Medicare, Medicaid plans exaggerate in-network mental health options, watchdogs say

Prenatal air pollution exposure may slow newborn brain development

Simple hand grip test may reveal your future obesity risk

Runx1 overexpression triggers early intervertebral disc degeneration

Smartphone app for muscle relaxation reduces migraine disability in ED patients

An age-old fear grows more common: ‘I’m going to die alone’

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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