Major Depressive Disorder News and Research

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Major Depressive Disorder (MDD) is a psychiatric condition characterized by depressed mood or anhedonia (significant loss of interest or pleasure). The condition affects more than 15.7 million adults and approximately 3 million adolescents (aged 13 to 17 years) in the USA each year.

Looking deep inside the brain to accurately diagnose bipolar disorder and depression

New research has found that neurons deep inside the brain could hold the key to accurately diagnosing bipolar disorder and depression.

4 Sep 2018

Study explores how social networks affect smoking outcomes in people with serious mental illness

People with serious mental illness have a reduced life expectancy of up to 25 years compared to the general population

24 Aug 2018

BrainsWay receives FDA clearance for Deep TMS system to treat adults with obsessive-compulsive disorder

BrainsWay Ltd., the parent company of BrainsWay USA, Inc., and a global leader in the advanced non-invasive treatment of brain disorders, today announces that it has received De Novo clearance from the U.S. Food and Drug Administration (FDA) for its deep transcranial magnetic stimulation (Deep TMS) system for the treatment of obsessive-compulsive disorder (OCD) in adults.

22 Aug 2018

Scientists make surprising discovery in nerve cells

Purkinje cells are a central part of the human cerebellum, the part of the brain that plays an important role in motor learning, fine motor control of the muscle, equilibrium and posture but also influences emotions, perception, memory and language.

10 Aug 2018

New AI algorithm helps predict medication response in patients with complex mood disorder

Mood disorders like major depressive disorder and bipolar disorder are often complex and hard to diagnose, especially among youth when the illness is just evolving.

9 Aug 2018

Researchers identify neural link between depression and sleep problems

The neural link between depression and sleep problems has been identified for the first time in a new study by researchers at the University of Warwick and Fudan University.

25 Jul 2018

Nitrate-cured meats may contribute to mania, study finds

An analysis of more than 1,000 people with and without psychiatric disorders has shown that nitrates-chemicals used to cure meats such as beef jerky, salami, hot dogs and other processed meat snacks-may contribute to mania, an abnormal mood state. Mania is characterized by hyperactivity, euphoria and insomnia.

18 Jul 2018

Scientists develop new understanding of how psychiatric diseases manifest and can be treated

Research scientists from The Feinstein Institute for Medical Research and the Donald and Barbara Zucker School of Medicine at Hofstra/Northwell in Hempstead, NY, in conjunction with their colleagues at Rockefeller University in New York City, have developed a new understanding of how certain psychiatric diseases - those that involve uncontrollable reactions to stimuli such as the high and low experiences attributed to bi-polar disorder, the impulsivity of an individual suffering from attention deficit hyperactivity disorder, and even suicidality - manifest and potentially can be treated. These findings were published today in Proceedings of the National Academy of Sciences.

3 Jul 2018

Massive analysis of genomes reveals insights into genetic overlap among psychiatric diseases

A massive undertaking by the Brainstorm Consortium to analyze the genomes of nearly 900,000 people has revealed important insights into the genetic overlap among some psychiatric diseases, as well as among personality traits.

21 Jun 2018

Scientists examine how depressive episode affects the memory with computational model

During a depressive episode the ability of the brain to form new brain cells is reduced. Scientists of the Ruhr-Universität Bochum examined how this affects the memory with a computational model.

8 Jun 2018

Computerized brain shows how depressive episodes affect memory

Scientists have used a computational model to show how depressive episodes affect the brain’s ability to store and recall memories.

8 Jun 2018

Mobile health intervention for people with serious mental illness as effective as clinic-based treatment

A mobile health intervention was found to be as effective as a clinic-based group intervention for people with serious mental illness in a new study published online today in Psychiatric Services.

25 May 2018

Study explores link between groundwater lithium and diagnoses of bipolar disorder, dementia

High groundwater concentration of lithium, a naturally occurring trace element, wasn't associated with any benefit in diagnoses of bipolar disorder or dementia when accounting for local health care resources and demographics, two factors that can cause mental health diagnosis rates to vary.

23 May 2018

Scientists identify cell types underlying schizophrenia

Scientists at Karolinska Institutet in Sweden and University of North Carolina, USA, have identified the cell types underlying schizophrenia in a new study published in Nature Genetics. The findings offer a roadmap for the development of new therapies to target the condition.

21 May 2018

Brain abnormality linked to general risk for mental illness

A new study by researchers at Duke University reports an abnormality in visual regions of the brain that is associated with a person's general risk for mental illness.

17 May 2018

National trial shows how high-tech strategies may change the field of mental health

A national research trial initiated by UT Southwestern in 2012 is generating the first set of results this year that provides an early glimpse into how such high-tech strategies may change the field of mental health.

16 May 2018

Akili Interactive closes $55 million financing to advance digital medicine platform for treatment of cognitive dysfunction

Akili Interactive, a leading prescription digital medicine company developing novel treatments for cognitive dysfunction, today announced that it has successfully closed a $55 million Series C financing led by Temasek.

9 May 2018

Study finds large, unmet need for mental health treatment in parents of multiples

Parents of twins and other multiple-birth children experience higher than average rates of depression, anxiety and other mental health issues, particularly during the first three months, according to a survey study in the May issue of Journal of Psychiatric Practice.

4 May 2018

HBP researchers develop new tool to examine role of genes in disease-relevant brain regions

Elucidating the way from genes to cognition requires detailed insight into how anatomical areas with specific gene activities contribute to brain function and dysfunction. Up to now, the scientific community has developed many separate brain atlases for different modalities and scales.

25 Apr 2018

Pitt researcher secures nearly $5 million NIH funding for 'Tic-Tac-Toe' RF coil system

The University of Pittsburgh houses a whole-body 7 Tesla magnetic resonance imager (7T MRI), one of the strongest human MRI devices in the world and a powerful imaging tool that allows researchers to gain a far better understanding of brain structure and function.

13 Apr 2018