Pathology News and Research

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Pathology is the study and diagnosis of disease through examination of organs, tissues, bodily fluids, and whole bodies (autopsies). The term also encompasses the related scientific study of disease processes, called General pathology. Medical pathology is divided in two main branches, Anatomical pathology and Clinical pathology. Veterinary pathology is concerned with animal disease whereas Phytopathology is the study of plant diseases.

Osteoprotegerin links bone metabolism to cardiovascular disease

Announcing a new article publication for Cardiovascular Innovations and Applications journal. Osteoprotegerin (OPG), a glycoprotein in the tumor necrosis factor superfamily, regulates bone metabolism by suppressing the formation and activation of osteoclasts.

13 Feb 2026

Early cognitive stimulation preserves memory in Alzheimer’s

A team from the Institute of Neurosciences of the University of Barcelona (UBneuro) has discovered that early and sustained cognitive stimulation can help preserve brain connectivity and memory in Alzheimer's disease, even in advanced stages of the pathology.

12 Feb 2026

FDA-approved anti-seizure drug could help fight Alzheimer's disease

While physicians and scientists have long known Alzheimer's disease involves the buildup of toxic protein fragments in the brain, they have struggled to understand how these harmful fragments are produced.

12 Feb 2026

Leica Biosystems revolutionizes histology workflows with global launch of the Leica CM1950 Cryostat with DualEcoTec Cooling System

Leica Biosystems, a Danaher company and a global leader in anatomic pathology solutions, is redefining histology workflows with the global launch of the Leica CM1950 Cryostat with DualEcoTec Cooling System.

From Leica Biosystems 12 Feb 2026

New roadmap integrates aging into Parkinson disease models

Even though aging is the largest risk factor for Parkinson's disease, the majority of research aimed at taming the able neurodegenerativeincur motor disease has largely left aging out of the mix.

11 Feb 2026

Study uncovers immune trigger behind vaccine-induced immune thrombocytopenia and thrombosis

A global research collaboration of scientists from McMaster University (Canada), Flinders University (Australia) and Universitätsmedizin Greifswald (Germany) uncovered why a small number of people developed dangerous blood clots after either receiving certain COVID‑19 vaccines or experiencing a natural adenovirus infection, and the answer lies in an unexpected case of misdirected targeting by the immune system.

11 Feb 2026

Advanced three-dimensional imaging maps vascular amyloid spread

Researchers at Niigata University have used advanced three-dimensional (3D) imaging to reveal how amyloid β (Aβ) deposits spread along blood vessels in the human brain in cerebral amyloid angiopathy (CAA).

11 Feb 2026

Alzheimer’s plaques decline after CAR-T immune cell treatment in preclinical study

Researchers engineered CD4+ chimeric antigen receptor T cells targeting fibrillar amyloid beta and tested them in a mouse Alzheimer model. The preclinical study showed reduced amyloid pathology and altered neuroimmune responses, supporting CAR-T immunotherapy as a potential future Alzheimer strategy.

11 Feb 2026

Transcription factor HOXD13 drives melanoma growth and immune evasion

A molecule that helps regulate gene activity has also been shown to drive skin cancer growth and tumors' ability to evade attack by the body's immune system, a new study shows.

11 Feb 2026

New guidance for the diagnosis and management of inherited hyperbilirubinemia

Inherited hyperbilirubinemia, encompassing Gilbert syndrome, Crigler-Najjar syndrome, Dubin-Johnson syndrome, and Rotor syndrome, represents a spectrum of disorders rooted in genetic defects affecting bilirubin metabolism and transport.

10 Feb 2026

Study reveals how inherited genetic abnormalities raise Barrett’s esophagus risk

Case Western Reserve University researchers have made a significant breakthrough in understanding Barrett's esophagus, a precancerous condition that dramatically increases the risk of developing esophageal adenocarcinoma, one of the fastest-spreading and deadliest forms of cancer.

10 Feb 2026

Preexisting flu immunity may offer baseline protection against avian influenza

Are seasonal flu antibodies also effective against avian flu? A team from the University of Geneva (UNIGE) has shown that a specific type of antibody associated with the former virus—already present throughout the population—may offer baseline protection against the latter.

10 Feb 2026

Engineered CAR-T cells reduce Alzheimer’s plaques in mice

Chimeric antigen receptor (CAR) T cell therapy, a type of immunotherapy that leverages the immune system to combat diseases, is a powerful treatment option for certain cancers.

9 Feb 2026

Study identifies link between gut bacteria and deterioration of the brain in ALS, dementia

A significant discovery by Case Western Reserve University researchers could change how doctors treat two of the most devastating neurodegenerative diseases.

9 Feb 2026

Research sheds light on the UK's growing synthetic opioid problem

Deaths due to synthetic opioids nitazenes have likely been underestimated by up to a third.

9 Feb 2026

Brain connectivity fingerprints differ in major depressive disorder

Major depressive disorder (MDD) is a debilitating condition that affects more than 246 million people worldwide, yet scientists have struggled to identify consistent brain markers that could improve diagnosis and treatment.

5 Feb 2026

Inhibiting PTP1B protein improves memory in Alzheimer’s disease models

Alzheimer's disease is often measured in statistics: millions affected worldwide, cases rising sharply, costs climbing into the trillions.

5 Feb 2026

Reprogrammed neutrophils promote tumor growth

Predicting tumor progression is one of the major challenges in oncology. Scientists at the University of Geneva (UNIGE) and the Ludwig Institute for Cancer Research have discovered that neutrophils, a type of immune cell, undergo reprogramming when they come into contact with the tumor ecosystem and contribute to its progression.

5 Feb 2026

Sub-terahertz biosensors enable label-free cancer cell identification

Early detection and accurate typing of cancer are critical for improving patient survival rates. While traditional pathology remains the gold standard, it often requires complex sample processing and chemical staining.

4 Feb 2026

Small molecule targets glioblastoma oncogene in preclinical studies

UVA Comprehensive Cancer Center scientists have identified a molecule that blocks the gene responsible for glioblastoma, raising hopes that the molecule could become a much-needed new treatment for the deadliest brain cancer.

4 Feb 2026