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Novel vaccine strategy could solve the challenge of implanted device infections

Patients with implanted medical devices like orthopedic joint replacements, pacemakers, and artificial heart valves run a small but significant risk that these devices get infected with bacterial pathogens.

4 Nov 2025

New review illuminates the intricate connections between gut microbiota and sleep regulation

A comprehensive review published today in Brain Medicine illuminates the intricate connections between gut microbiota and sleep regulation, establishing the microbiota-gut-brain axis as a critical pathway in understanding and potentially treating sleep disorders.

4 Nov 2025

Researchers use genetic engineering to create “product-ready” snakebite antivenom

An international team of researchers has used genetic engineering to create the first ever “product-ready” antivenom for snakes such as cobras and mambas.

4 Nov 2025

Large-scale foundation model reconstructs how cells interact within tissues

Researchers at Helmholtz Munich and the Technical University of Munich (TUM) have developed Nicheformer, the first large-scale foundation model that integrates single-cell analysis with spatial transcriptomics.

3 Nov 2025

Scientists explore why black rice deserves a bigger place in modern diets

Researchers reviewed the nutritional composition, therapeutic benefits, and industrial uses of black rice, highlighting its potential as a functional food. The study highlights the role of black rice in managing blood sugar, cholesterol, and inflammation, while also advocating for more robust human trials and sustainable cultivation methods.

2 Nov 2025

Lactate and lactylation drive metabolic, epigenetic reprogramming in gynecological cancers

Lactate, once considered a metabolic waste product, is now recognized as a key regulator of cellular homeostasis and disease progression.

31 Oct 2025

Studies identify complementary approaches to overcome drug resistance in KRAS G12C–mutant lung cancer

Two companion studies published in Cancer Research from scientists at Moffitt Cancer Center identify distinct but complementary approaches to overcoming drug resistance in KRAS G12C–mutant non-small cell lung cancer.

31 Oct 2025

Oligodendrocyte progenitor cells promote blood vessel growth after stroke

Stroke is a leading cause of death and disability, affecting 1 in 4 people during their lifetime. Stroke happens when blood vessels in the brain get clogged or damaged, impairing blood flow and oxygen supply to the brain, which leads to death of neurons and other brain cells.

30 Oct 2025

New evidence-based points to consider and consensus definitions for people with psoriatic arthritis

Some people with psoriatic arthritis (PsA) may have disease that is difficult to manage (D2M) or does not respond to treatment. EULAR - The European Alliance of Associations for Rheumatology - has released new evidence-based points to consider and consensus definitions for these groups.

30 Oct 2025

Advances in diagnosis and management of systemic light chain amyloidosis

Systemic light chain (AL) amyloidosis is a rare and life-threatening disorder characterized by the deposition of misfolded immunoglobulin light chains as insoluble amyloid fibrils in various tissues and organs, leading to progressive structural and functional impairment.

30 Oct 2025

Global Virus Network announces the addition of three new Centers of Excellence

The Global Virus Network (GVN), a coalition of leading medical virologists representing 80+ Centers of Excellence and Affiliates in 40+ countries, today announced the addition of three new Centers of Excellence: the USF Health Institute for Translational Virology and Innovation at the University of South Florida (USF) in Tampa, Florida, USA, the Department of Microbiology, Immunology and Parasitology at the Federal University of São Paulo (UNIFESP) in Brazil, and the Pathogen Research Centre (PaRC) at Western University in Canada.

30 Oct 2025

Therapeutic potential of Scleromitrion diffusum in gastric cancer treatment

Gastric cancer remains a major global health challenge, characterized by high mortality and limited therapeutic efficacy, especially in advanced stages.

30 Oct 2025

Two microbial metabolites compete to control the cells' protein building machinery

The microbiome-the trillions of bacteria, viruses, and fungi that live quietly in our body-plays a crucial role in shaping human health by providing a variety of micronutrients necessary for vital functions.

30 Oct 2025

Understanding the role of m6A methylation in acute lung injury pathogenesis

Acute lung injury (ALI) is a critical clinical condition characterized by diffuse inflammation of the lung parenchyma and intractable hypoxemia, typically caused by factors, such as trauma, pneumonia, shock, and sepsis.

30 Oct 2025

Fundamental challenges and cutting-edge strategies in developing new GBM CAR-T therapies

Glioblastoma (GBM), the most aggressive primary brain tumor, continues to portend a poor prognosis with median survival under two years, despite standard care involving surgery, radiation, and temozolomide chemotherapy.

30 Oct 2025

Systematic analysis reveals psilocybin's impact on obsessive-compulsive behaviors

A systematic review published today in Psychedelics by Mr. James Gattuso and colleagues at the Florey Institute of Neuroscience and Mental Health synthesizes clinical and preclinical evidence on psilocybin's effects on obsessive-compulsive behaviors, revealing consistent therapeutic potential across human patients and validated animal models.

29 Oct 2025

Translation News and Research

Novel vaccine strategy could solve the challenge of implanted device infections

New review illuminates the intricate connections between gut microbiota and sleep regulation

Researchers use genetic engineering to create “product-ready” snakebite antivenom

Large-scale foundation model reconstructs how cells interact within tissues

Scientists explore why black rice deserves a bigger place in modern diets

Lactate and lactylation drive metabolic, epigenetic reprogramming in gynecological cancers

Studies identify complementary approaches to overcome drug resistance in KRAS G12C–mutant lung cancer

Oligodendrocyte progenitor cells promote blood vessel growth after stroke

New evidence-based points to consider and consensus definitions for people with psoriatic arthritis

Advances in diagnosis and management of systemic light chain amyloidosis

Global Virus Network announces the addition of three new Centers of Excellence

Therapeutic potential of Scleromitrion diffusum in gastric cancer treatment

Two microbial metabolites compete to control the cells' protein building machinery

Understanding the role of m6A methylation in acute lung injury pathogenesis

Fundamental challenges and cutting-edge strategies in developing new GBM CAR-T therapies

Systematic analysis reveals psilocybin's impact on obsessive-compulsive behaviors

AI indelibly transforms solid tumor drug development

Study aims to examine the association between arsenic exposure and MASLD

Exploring the gut-brain-immune axis in neurodegeneration

New technology improves the efficiency of protein production in E. coli

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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