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Breakthrough study defines ideal interval for immunotherapy and liver transplants

Hepatocellular carcinoma (HCC) represents about 80 to 90% of cases of primary liver cancer. On a global level, 905,700 new cases and 830,200 deaths were registered in 2020 according to the World Health Organization.

6 Mar 2025

Study shows benefits of GLP-1 drugs for kidney transplant recipients with type 2 diabetes

Kidney transplant recipients with type 2 diabetes treated with a new class of anti-obesity drugs were less likely to experience organ failure and survived longer, a new study shows.

5 Mar 2025

Stem cell therapy for cornea injuries demonstrates remarkable results in clinical trial

An expanded clinical trial that tested a groundbreaking, experimental stem cell treatment for blinding cornea injuries found the treatment was feasible and safe in 14 patients who were treated and followed for 18 months, and there was a high proportion of complete or partial success.

4 Mar 2025

New CRISPR-based test enhances diagnosis of life-threatening fungal infection

Tulane University researchers have developed a CRISPR-based test that diagnoses Pneumocystis jirovecii pneumonia (PJP) - a life-threatening fungal infection primarily affecting children and immunocompromised patients - more quickly and less invasively, according to a new study published in the Journal of Clinical Investigation.

3 Mar 2025

Synthetic microbiome therapy offers new hope against C. difficile infections

A synthetic microbiome therapy, tested in mice, protects against severe symptoms of a gut infection that is notoriously difficult-to-treat and potentially life threatening in humans, according to a team of researchers at Penn State.

3 Mar 2025

Pioneering the world’s first CRISPR medicine for sickle cell disease

When Vijay Sankaran was an MD-PhD student at Harvard Medical School in the mid-2000s, one of his first clinical encounters was with a 24-year-old patient whose sickle cell disease left them with almost weekly pain episodes.

3 Mar 2025

Study demonstrates successful gene therapy for maple syrup urine disease

A study led by UMass Chan researchers demonstrated that a gene therapy to correct a mutation that causes maple syrup urine disease (MSUD) prevented newborn death, normalized growth, restored coordinated expression of the affected genes and stabilized biomarkers in a calf as well as in mice.

28 Feb 2025

Grapefruit juice and its effects on prescription drugs

Grapefruit juice can interfere with how certain medications work by affecting drug metabolism and absorption, leading to either increased side effects or reduced effectiveness. The FDA requires warnings on some drugs due to these interactions, making it essential to check labels and consult healthcare providers.

28 Feb 2025

First-ever clinical trials evaluate fenofibrate as treatment for HPV-related cancers

A team from University Hospitals Seidman Cancer Center is launching the nation's first-ever clinical trials evaluating the cholesterol drug fenofibrate (Triglide, Fibricor, Lipofen) as an investigational and potential treatment for patients with HPV+ cervical and HPV+ head and neck cancer (HNSCC).

28 Feb 2025

The brain-gut microbiota axis: Impact on mental health & potential treatment avenues

To be decided by the editor

From Atlantia Clinical Trials 28 Feb 2025

UCSF study reveals lungs as source of hematopoietic stem cells

Red blood cells carry oxygen from the lungs to every other organ, and blood-forming stem cells must make about 200 billion new red blood cells each day to keep the oxygen flowing.

28 Feb 2025

Innovative treatment method offers hope for treating wet AMD

Age-related macular (AMD) degeneration is a leading cause of vision impairment and blindness in the elderly population.

27 Feb 2025

Scientists pioneer fecal transplant capsules to enhance pancreatic cancer treatment

Scientists at Lawson Research Institute (Lawson) of St. Joseph's Health Care London and London Health Sciences Centre Research Institute (LHSCRI) are the first in the world to study fecal transplants using capsules containing microbes from the gut of healthy volunteers to improve the response of patients with advanced pancreatic cancer to chemotherapy.

26 Feb 2025

Water-only fasting boosts human growth hormone without weight loss

Fasting for 24 hours increases human growth hormone (HGH) levels independently of weight loss, with individuals with lower baseline HGH experiencing the most significant increases. The study suggests metabolic benefits from fasting, particularly for those with lower HGH levels.

25 Feb 2025

Pig kidney transplant patient completes recovery and returns home

Three months after her breakthrough surgery at NYU Langone Health, Towana Looney, the longest-living recipient of a genetically engineered pig kidney, is headed back home to Alabama.

25 Feb 2025

Sleep disruption linked to inflammatory immune changes and health risks

New research reveals insight into the impact sleep quality has on a person's immune system, and how it could be linked to the development of diseases such as obesity, diabetes, and cardiovascular diseases.

24 Feb 2025

Engineered blood vessel cells boost islet transplant success in diabetes treatment

Adding engineered human blood vessel-forming cells to islet transplants boosted the survival of the insulin-producing cells and reversed diabetes in a preclinical study led by Weill Cornell Medicine investigators.

21 Feb 2025

FDA ensures blood safety through five layers of safeguards

Every day, hospitals throughout the U.S. transfuse blood or blood components, such as platelets, to save the lives of people who are in car crashes, and victims of fires and other emergencies.

20 Feb 2025

CPRIT awards nearly $23 million to MD Anderson for cancer research projects

The University of Texas MD Anderson Cancer Center today was awarded nearly $23 million from the Cancer Prevention and Research Institute of Texas (CPRIT) in support of 20 cancer research projects to advance new breakthroughs in discovery, translational, clinical and prevention science.

20 Feb 2025

Vitamin E supplementation may reduce food allergy development in newborns

New research found that supplementing maternal diet with α-tocopherol, a form of vitamin E, can reduce the development of food allergy and anaphylaxis in newborn mice.

19 Feb 2025