Alzheimer's Disease News and Research

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Alzheimer's disease (AD) is an irreversible, progressive brain disease that slowly destroys memory and thinking skills and, eventually, the ability to carry out the simplest tasks of daily living. In most people with AD, symptoms first appear after age 60. AD is the most common cause of dementia among older people, but it is not a normal part of aging. Dementia refers to a decline in cognitive function that interferes with daily life and activities. AD starts in a region of the brain that affects recent memory, then gradually spreads to other parts of the brain. Although treatment can slow the progression of AD and help manage its symptoms in some people, currently there is no cure for this devastating disease.

Sage launches new web-based tool that helps explore curated genomic analyses of Alzheimer's

Sage Bionetworks announces the launch of the Agora platform an interactive, web-based tool that allows researchers to explore curated genomic analyses of Alzheimer's Disease, including a list of early candidate target nominations for AD.

20 Jul 2018

Alzheimer’s Research UK calls for urgent investment in dementia research

Alzheimer’s Research UK is calling for urgent investment in dementia research, following new statistics that show the condition accounted for 13% of all UK deaths last year. The figures were released by the Office for National Statistics today (Wednesday 18 July).

20 Jul 2018

Whole-brain LIPUS therapy improves cognitive dysfunction in mice simulating dementia, Alzheimer's

Ultrasound waves applied to the whole brain improve cognitive dysfunction in mice with conditions simulating vascular dementia and Alzheimer's disease.

20 Jul 2018

Top AI companies join hands to discover novel drugs for DMD

Insilico Medicine a leader in artificial intelligence for drug discovery, biomarker development and aging research, announced a research collaboration agreement with A2A Pharmaceuticals, Inc. A2A is a biotechnology company headquartered in New York and focused on development of novel drugs for unmet needs in oncology, drug resistant bacterial infections, and other life threatening diseases.

20 Jul 2018

Sleep disturbances associated with higher dementia risk

Researchers at Karolinska Institutet in Sweden report that sleep disturbances in midlife or in late life are associated with a higher risk for developing dementia in old age. The results are published in Alzheimer's & Dementia: The Journal of the Alzheimer's Association.

20 Jul 2018

Study finds link between anesthesia, surgery and subtle cognitive decline in older adults

In adults over 70, exposure to general anesthesia and surgery is associated with a subtle decline in memory and thinking skills, according to new Mayo Clinic research.

19 Jul 2018

New proteomics studies help gain more insights into Alzheimer's, cancer and listeriosis

The brains of people with Alzheimer's disease contain many protein aggregates outside of cells, known as plaques. These are mainly made of the peptide amyloid-beta, which is released from the plasma membrane when the protease BACE1 cleaves its membrane-anchored precursor protein.

19 Jul 2018

Woman's pregnancy history may be linked to Alzheimer's disease risk

A woman's history of pregnancy may affect her risk of Alzheimer's disease decades later, according to a study published in the July 18, 2018, online issue of Neurology, the medical journal of the American Academy of Neurology.

19 Jul 2018

Researchers identify new compound that protects against neurodegeneration

Researchers from the University of Liverpool have identified a new compound that protects against neurodegeneration in nematode worms. The discovery may enable novel treatments for human neurodegenerative diseases to be developed in the future.

18 Jul 2018

Fish consumption associated with lower risk of early death

Consumption of fish and long-chain omega-3 fatty acids was associated with lower risks of early death in a Journal of Internal Medicine study.

18 Jul 2018

Military personnel with head trauma and football players with suspected CTE show similar brain changes

In a small study of military personnel who had suffered head trauma and had reported memory and mood problems, UCLA researchers found brain changes similar to those seen in retired football players with suspected chronic traumatic encephalopathy, a degenerative brain disease linked to repeated blows to the head.

18 Jul 2018

Researchers lament the unmet promise of a miracle drug for Alzheimer disease

In an editorial entitled "The Unmet Promise of a Miracle Drug for Alzheimer's Disease: Implications for Practice, Policy, and Research," Malaz Boustani, MD, MPH, a Regenstrief Institute research scientist and the founding director of the Indiana University Center for Health Innovation and Implementation Science, and co-authors Philip D. Sloane, MD, MPH and Sheryl Zimmerman, PhD, of the University of North Carolina at Chapel Hill, lament the unmet promise of a miracle drug for Alzheimer disease but are heartened by what they see as encouraging improvements in care for a growing population of older adults, many with dementia.

17 Jul 2018

New super-resolution 'nanoscope' provides insight into progression of Alzheimer's disease

Recent studies show that 40 percent of Americans over the age of 85 have Alzheimer's disease, and that the disease begins 10 to 20 years before people show up at the doctor's office with memory problems.

17 Jul 2018

Insight into causes, types and treatment of aphasia

Most people who are familiar with the term associate it with stroke. But aphasia, an impairment of language, is not always caused by stroke.

16 Jul 2018

New study documents symptoms of people before they acquire multiple sclerosis

During the five years before people develop the first clinically recognized signs of multiple sclerosis, they are up to four times more likely to be treated for nervous system disorders such as pain or sleep problems, and are 50 per cent more likely to visit a psychiatrist, according to new research from the University of British Columbia.

16 Jul 2018

Researchers seek to understand role of APOE mutation in Alzheimer's disease

If you had your genome sequenced and the report says you have the APOEε4 mutation, it does not mean you are definitely going to get Alzheimer's disease.

16 Jul 2018

Researchers uncover how cells invite corrupted proteins inside

Vampires can turn humans into vampires, but to enter a human's house, they must be invited in. Researchers at the UT Southwestern Medical Center, writing in the Journal of Biological Chemistry, have uncovered details of how cells invite inside corrupted proteins that can turn normal proteins corrupt, leading to neurodegenerative diseases such as Alzheimer's and Parkinson's diseases.

16 Jul 2018

Neurogenesis underlies the brain's capacity for new memories

The ability to obtain new memories in adulthood may depend on neurogenesis -- the generation of new neurons in the hippocampus -- to clear out old memories that have been safely stored in the cortex, according to research in male rats published in JNeurosci.

13 Jul 2018

Athletes with ADHD may be at greater risk for anxiety and depression after concussion

Athletes who have attention deficit hyperactivity disorder may be at greater risk for experiencing persistent anxiety and depression after a concussion than people who do not have ADHD, according to a preliminary study released today that will be presented at the American Academy of Neurology's Sports Concussion Conference in Indianapolis, July 20 to 22, 2018. ADHD is a brain disorder that affects attention and behavior.

12 Jul 2018

Novel therapeutic approach alleviates ALS-related muscular atrophy in mouse models

Supplementing a single protein found in the spinal cord could help prevent symptoms of Lou Gehrig's disease, according to a new study out of Case Western Reserve University School of Medicine.

12 Jul 2018

Alzheimer's Disease News and Research

Further Reading

Sage launches new web-based tool that helps explore curated genomic analyses of Alzheimer's

Alzheimer’s Research UK calls for urgent investment in dementia research

Whole-brain LIPUS therapy improves cognitive dysfunction in mice simulating dementia, Alzheimer's

Top AI companies join hands to discover novel drugs for DMD

Sleep disturbances associated with higher dementia risk

Study finds link between anesthesia, surgery and subtle cognitive decline in older adults

New proteomics studies help gain more insights into Alzheimer's, cancer and listeriosis

Woman's pregnancy history may be linked to Alzheimer's disease risk

Researchers identify new compound that protects against neurodegeneration

Fish consumption associated with lower risk of early death

Military personnel with head trauma and football players with suspected CTE show similar brain changes

Researchers lament the unmet promise of a miracle drug for Alzheimer disease

New super-resolution 'nanoscope' provides insight into progression of Alzheimer's disease

Insight into causes, types and treatment of aphasia

New study documents symptoms of people before they acquire multiple sclerosis

Researchers seek to understand role of APOE mutation in Alzheimer's disease

Researchers uncover how cells invite corrupted proteins inside

Neurogenesis underlies the brain's capacity for new memories

Athletes with ADHD may be at greater risk for anxiety and depression after concussion

Novel therapeutic approach alleviates ALS-related muscular atrophy in mouse models

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