Pathology News and Research

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Pathology is the study and diagnosis of disease through examination of organs, tissues, bodily fluids, and whole bodies (autopsies). The term also encompasses the related scientific study of disease processes, called General pathology. Medical pathology is divided in two main branches, Anatomical pathology and Clinical pathology. Veterinary pathology is concerned with animal disease whereas Phytopathology is the study of plant diseases.

MGH researchers identify potential markers of lung cancer

By examining both blood samples and tumor tissues from patients with non-small-cell lung cancer, investigators at Massachusetts General Hospital have identified markers that can distinguish between major subtypes of lung cancer and can accurately identify lung cancer stage.

16 Jul 2019

New study uncovers 3D structure of toxin responsible for C. diff infection

A new study, led by researchers from the University of California, Irvine, uncovers the long-sought-after, three-dimensional structure of a toxin primarily responsible for devastating Clostridium difficile infection.

16 Jul 2019

An active brain and body associated with reduced risk of dementia

A team of researchers at the Tianjin Medical University in China wanted to explore whether accumulation over a lifetime of cognitive and social activities are linked to a slower rate of memory loss, hence, a lower risk of developing dementia, despite brain pathologies.

14 Jul 2019

Artificial intelligence can help accurately predict acute kidney injury in burn patients

Many burn victims suffer acute kidney injury (AKI), but early recognition of AKI remains challenging. Now an Artificial Intelligence / Machine Learning (AI/ML) model developed at UC Davis Health and reported in a new study can predict acute kidney injury quicker and more accurately than ever.

12 Jul 2019

Research questions whether tongue-tie surgery to improve breastfeeding is needed

New research raises questions as to whether too many infants are getting tongue-tie and lip tether surgery (also called frenulectomy) to help improve breastfeeding, despite limited medical evidence supporting the procedure.

12 Jul 2019

Arthroscopy more accurate than MRI for chondral defects of the knee, study finds

Using arthroscopy to stage a lesion in the chondral area of the knee is more accurate than magnetic resonance imaging, according to researchers from the Rothman Institute, La Jolla, Calif. The findings were presented today at the American Orthopedic Society of Sports Medicine Annual Meeting.

12 Jul 2019

New therapeutic food boosts key growth-promoting gut microbes in malnourished children

A new type of therapeutic food, specifically designed to repair the gut microbiomes of malnourished children, is superior to standard therapy in an initial clinical trial conducted in Bangladesh.

12 Jul 2019

Researchers identify potential drug target for multiple cancer types

A research team headed by scientists at University of California San Diego School of Medicine and the Ludwig Institute for Cancer Research at UC San Diego has identified an enzyme involved in remodeling the plasma membrane of multiple cancer cell types that is critical to both survival of tumors and their uncontrolled growth.

11 Jul 2019

Study highlights the need for larger Alzheimer's drug trials that intervene much earlier

There are currently no drugs that stop or inhibit Alzheimer's disease. Despite drug trials showing plaque reduction in the brain, the patients' cognitive function did not improve.

11 Jul 2019

Sorting protein in neurons protects against neurodegenerative disorders

Like a sorting machine in an assembly line, a molecule known as VPS35 detects and removes defective proteins from neurons.

10 Jul 2019

Pitt/UPMC researchers to lead large clinical trial to test red cell exchange in sickle cell disease

Medical advances have dramatically increased the life expectancy of patients with sickle cell disease, but as patients are living longer, they are increasingly experiencing organ damage leading to early death.

10 Jul 2019

Age-related risk of Alzheimer's explained at the molecular level

Studies have shown that Alzheimer’s disease (AD) incidence increases with age. This association with age also correlates with deposits of abnormal tau protein in the brain found a new study.

9 Jul 2019

Comparing ability of human listeners and computational models to rate health state of infants

Crying is, for babies, the earliest way of expressing and communicating needs like hunger, pain, discomfort or tiredness.

9 Jul 2019

Researchers use artificial intelligence to predict molecular classification of colorectal cancer

Treating physicians need information about the molecular subtype of the tumor if they are to provide targeted therapy for colorectal carcinoma.

4 Jul 2019

Findings suggest new ways to help the immune system fight pancreatic cancer

Findings published today in the journal Science Translational Medicine suggest that a type of white blood cell called tumor associated macrophages that have been deceived by pancreatic cancer cells into not attacking them can be "re-programmed" by a specially designed molecule that activates a protein found on their surfaces.

4 Jul 2019

Immune-boosting compound could make pancreatic cancers susceptible to immunotherapy

Pancreatic cancer is especially challenging to treat – only eight percent of patients are still alive five years after diagnosis.

4 Jul 2019

Mice study suggests potential treatment approach for MS in humans

For decades medical researchers have known that an effective way to combat multiple sclerosis (MS) would be to suppress the human immune system, since the debilitating disease is caused by the immune system 'mistakenly' attacking tissues in the spine and brain.

3 Jul 2019

Dundee and Bukwang Pharm announce partnership to develop new drug for Parkinson's

The University of Dundee's Drug Discovery Unit has announced a multi-million-pound partnership with Korea-based Bukwang Pharmaceutical Company in a bid to develop a new drug treatment for Parkinson's disease.

3 Jul 2019

Large doses of traditional chemotherapy drug spur immune system attack on cancer cells

More than 60 years ago, British physician Denis Parsons Burkitt and his associates achieved one of the signal successes in cancer medicine when they cured children in sub-Saharan Africa with a form of lymphoma by treating them with high doses of the chemotherapy drug cyclophosphamide.

2 Jul 2019

CAP opens public comment period for updated WSI guideline

Keeping pace with the growth in clinical applications for whole slide imaging and digital pathology, the College of American Pathologists, in collaboration with the American Society for Clinical Pathology and the Association for Pathology Informatics, is updating its 2013 guideline "Validating Whole Slide Imaging for Diagnostic Purposes in Pathology."

29 Jun 2019

Pathology News and Research

Further Reading

MGH researchers identify potential markers of lung cancer

New study uncovers 3D structure of toxin responsible for C. diff infection

An active brain and body associated with reduced risk of dementia

Artificial intelligence can help accurately predict acute kidney injury in burn patients

Research questions whether tongue-tie surgery to improve breastfeeding is needed

Arthroscopy more accurate than MRI for chondral defects of the knee, study finds

New therapeutic food boosts key growth-promoting gut microbes in malnourished children

Researchers identify potential drug target for multiple cancer types

Study highlights the need for larger Alzheimer's drug trials that intervene much earlier

Sorting protein in neurons protects against neurodegenerative disorders

Pitt/UPMC researchers to lead large clinical trial to test red cell exchange in sickle cell disease

Age-related risk of Alzheimer's explained at the molecular level

Comparing ability of human listeners and computational models to rate health state of infants

Researchers use artificial intelligence to predict molecular classification of colorectal cancer

Findings suggest new ways to help the immune system fight pancreatic cancer

Immune-boosting compound could make pancreatic cancers susceptible to immunotherapy

Mice study suggests potential treatment approach for MS in humans

Dundee and Bukwang Pharm announce partnership to develop new drug for Parkinson's

Large doses of traditional chemotherapy drug spur immune system attack on cancer cells

CAP opens public comment period for updated WSI guideline

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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