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Advanced brain mapping reveals neuronal subtypes and their connections

Scientists at the Salk Institute are unveiling a new brain-mapping neurotechnology called Single Transcriptome Assisted Rabies Tracing (START). The cutting-edge tool combines two advanced technologies - monosynaptic rabies virus tracing and single-cell transcriptomics - to map the brain's intricate neuronal connections with unparalleled precision.

30 Sep 2024

Immunotherapy timing key to survival in small cell lung cancer treatment

People with limited-stage small cell lung cancer may benefit from adding immunotherapy to chemoradiation, but not if both treatments are given at the same time, new research finds.

30 Sep 2024

Standard chemoradiation outperforms de-intensified treatments in HPV-associated oropharyngeal cancer

Researchers looking to de-intensify radiation treatments for people with early-stage, HPV-associated oropharyngeal cancer to prevent long-term side effects halted a large, randomized phase II/III trial after patients in the control arm reached a record high, two-year progression-free survival rate of 98%.

30 Sep 2024

Outpatient CAR-T therapy shows promise for treating lymphoma patients

In the largest prospective study to date examining the use of chimeric antigen receptor (CAR)-T therapy in a community setting on an outpatient basis, patients with relapsed or refractory large B-cell lymphoma (LBCL) responded well to treatment with few serious side effects, according to results published today in Blood Advances.

30 Sep 2024

New treatment strategy targets somatostatin to prevent blood sugar drops in type 1 diabetes

Inhibiting the hormone somatostatin may be a new treatment strategy to prevent dangerous blood glucose drops in type 1 diabetes.

30 Sep 2024

AI-powered blood test promises early detection of ovarian cancer

A blood test that uses artificial intelligence (AI) to detect cancer-related genetic changes and protein biomarkers could help screen women for early signs of ovarian cancer, according to a study by researchers at the Johns Hopkins Kimmel Cancer Center in collaboration with several other institutions in the United States and Europe.

30 Sep 2024

Study explores whether certain brain proteins may play a role in Alzheimer's development

With a four-year, $3.3 million grant from the National Institutes of Health (NIH), researchers from Case Western Reserve University will study whether certain brain proteins may play a role in the development of Alzheimer's disease.

30 Sep 2024

Discovery of antibodies that boost complement activation against K. pneumoniae

Researchers investigate antibody-dependent complement activation during Klebsiella pneumoniae infection.

30 Sep 2024

Regulating iron overload: Liraglutide's potential benefits

Researchers assess the role of liraglutide in regulating iron metabolism in a mouse model of hereditary hemochromatosis.

30 Sep 2024

$Scientists discover potential new treatment for heart failure with preserved ejection fraction$

Scientists discover potential new treatment for heart failure with preserved ejection fraction

Duke-NUS scientists and their collaborators have discovered a potential new treatment for heart failure with preserved ejection fraction (HFpEF), a type of heart disease that is notoriously difficult to treat.

30 Sep 2024

Over 80% of women are iron deficient by their third trimester

Iron deficiency is prevalent among pregnant women, impacting health outcomes. This study emphasizes the importance of monitoring and nutrition during pregnancy.

30 Sep 2024

Researchers identify a protein that recharges T cells for long-lasting cancer remission

Research shows Fc–IL-4 revitalizes exhausted CD8+ T cells, boosting antitumor responses and highlighting the potential of combining type 1 and type 2 immunity.

30 Sep 2024

How viral persistence and immune dysfunction drive long COVID

Study explores the biological drivers and mechanisms of long COVID, shedding light on its epidemiology and potential therapeutic interventions. It emphasizes the role of viral persistence, immune dysfunction, and coagulation in the development of this condition.

29 Sep 2024

Exploring the role of chemokines in atrial fibrillation development

Announcing a new article publication for Cardiovascular Innovations and Applications journal. Chemokines are a subclass of cytokines, a large family of small secreted proteins that communicate via G protein-coupled heptahelical chemokine receptors on the cell surface.

29 Sep 2024

Brusatol may serve as potential adjuvant therapy for pancreatic ductal adenocarcinoma

Announcing a new publication for Acta Materia Medica journal. Chemoresistance to gemcitabine (Gem) remains a substantial obstacle in the treatment of pancreatic ductal adenocarcinoma carcinoma (PDAC).

29 Sep 2024

Diet and gut dysbiosis linked to rheumatoid arthritis

Review highlights how gut dysbiosis and dietary factors are linked to rheumatoid arthritis, influencing disease progression and inflammation. Researchers explore how specific diets may help modulate the gut microbiome to improve symptoms.

29 Sep 2024

WHO announces recommended viral composition for 2025 influenza vaccines

The World Health Organization (WHO) today announced the recommendations for the viral composition of influenza vaccines for the 2025 influenza season in the southern hemisphere.

27 Sep 2024

Study shows how individual brain cells in the hippocampus respond to pronouns

A new study shows how individual brain cells in the hippocampus respond to pronouns. "This may help us unravel how we remember what we read."

27 Sep 2024

Estrogen found to promote tumor growth in breast cancers without receptors

Estrogens are known to drive tumor growth in breast cancer cells that carry its receptors, but a new study by Duke Cancer Institute researchers unexpectedly finds that estrogens play a role in fueling the growth of breast cancers without the receptors, as well as numerous other cancers.

27 Sep 2024

Study highlights potential for targeting macrophages to improve rheumatoid arthritis outcomes

Currently there are no cures for rheumatoid arthritis (RA) which affects 40,000 people in Ireland. The disease costs an estimated €20,000 per patient, per year with an overall cost to the health system of ~€544 million.

27 Sep 2024

B Cell News and Research

Advanced brain mapping reveals neuronal subtypes and their connections

Immunotherapy timing key to survival in small cell lung cancer treatment

Standard chemoradiation outperforms de-intensified treatments in HPV-associated oropharyngeal cancer

Outpatient CAR-T therapy shows promise for treating lymphoma patients

New treatment strategy targets somatostatin to prevent blood sugar drops in type 1 diabetes

AI-powered blood test promises early detection of ovarian cancer

Study explores whether certain brain proteins may play a role in Alzheimer's development

Discovery of antibodies that boost complement activation against K. pneumoniae

Regulating iron overload: Liraglutide's potential benefits

Scientists discover potential new treatment for heart failure with preserved ejection fraction

Over 80% of women are iron deficient by their third trimester

Researchers identify a protein that recharges T cells for long-lasting cancer remission

How viral persistence and immune dysfunction drive long COVID

Exploring the role of chemokines in atrial fibrillation development

Brusatol may serve as potential adjuvant therapy for pancreatic ductal adenocarcinoma

Diet and gut dysbiosis linked to rheumatoid arthritis

WHO announces recommended viral composition for 2025 influenza vaccines

Study shows how individual brain cells in the hippocampus respond to pronouns

Estrogen found to promote tumor growth in breast cancers without receptors

Study highlights potential for targeting macrophages to improve rheumatoid arthritis outcomes

Using single B cell screening to boost antibody discovery eBook

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How ELRIG Is Helping Mid-Career Scientists Navigate Leadership, Career Change and Redundancy

The role of UV-Vis in biopharma QC

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