Drug Discovery News and Research

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The drug discovery process begins with recognizing a disease or clinical condition in which there is a lack of adequate medical treatment. Once a potential drug has been identified, pre-clinical research can begin. This process includes several stages; the first of which involves identifying and validating the prospective drug’s target through assay development, high throughput screening, hit identification and finally, lead optimization. Once the pre-clinical process is complete, the newly synthesized drug candidate is selected for future clinical development.
Human amniotic fluid skin cells "reprogrammed" to pluripotency

Human amniotic fluid skin cells "reprogrammed" to pluripotency

Kinexus Bioinformatics launches new peptide synthesis facility

Kinexus Bioinformatics launches new peptide synthesis facility

Houston scientists unveil new technique for growing 3-D cell cultures

Houston scientists unveil new technique for growing 3-D cell cultures

CytRx plans five Phase 2 clinical trials with oncology drug candidates

CytRx plans five Phase 2 clinical trials with oncology drug candidates

LLS, FORMA Therapeutics collaborate to develop small molecule compounds against Bcl-6

LLS, FORMA Therapeutics collaborate to develop small molecule compounds against Bcl-6

Caliper Life Sciences enters into settlement agreement with Shimadzu and its subsidiary Shimadzu Scientific Instruments

Caliper Life Sciences enters into settlement agreement with Shimadzu and its subsidiary Shimadzu Scientific Instruments

Two controlled environmental variables to preclinical mice tests can reduce costly false positives: Study

Two controlled environmental variables to preclinical mice tests can reduce costly false positives: Study

Brain Science Institute, Eisai sign licensing agreement to develop GCPII inhibitors

Brain Science Institute, Eisai sign licensing agreement to develop GCPII inhibitors

UVA, Merck collaborate to discover novel drugs for women's reproductive health

UVA, Merck collaborate to discover novel drugs for women's reproductive health

BeaconEquity.com announces investment report featuring NexMed

BeaconEquity.com announces investment report featuring NexMed

TechniScan utilizes NVIDIA Tesla GPUs in WBU system for diagnostic breast imaging

TechniScan utilizes NVIDIA Tesla GPUs in WBU system for diagnostic breast imaging

StemCells reports net loss of $5.23M for fourth-quarter fiscal 2009

StemCells reports net loss of $5.23M for fourth-quarter fiscal 2009

Data from novel Hedgehog pathway inhibitor program to be presented at upcoming conferences

Data from novel Hedgehog pathway inhibitor program to be presented at upcoming conferences

Ampicillin activates torsinA, improves cell function to reduce movement disorders

Ampicillin activates torsinA, improves cell function to reduce movement disorders

Lowering levels of Coonexin46 with use of siRNA will help prevent tumor formation

Lowering levels of Coonexin46 with use of siRNA will help prevent tumor formation

Lonza acquires access to PCA technology patent portfolio

Lonza acquires access to PCA technology patent portfolio

Novel protein haditoxin in King Cobra's venom discovered

Novel protein haditoxin in King Cobra's venom discovered

Restructuring results in reduction of Exelixis’ workforce by 40% and increases financial strength

Restructuring results in reduction of Exelixis’ workforce by 40% and increases financial strength

RepRegen's Strontium-based bioactive glass platform encourages osteoblast cell activity and proliferation

RepRegen's Strontium-based bioactive glass platform encourages osteoblast cell activity and proliferation

Three researchers to be honored with SBS Award for achievement in biomolecular sciences and lead discovery

Three researchers to be honored with SBS Award for achievement in biomolecular sciences and lead discovery

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