Antidepressant News and Research

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Antidepressants are medicines that treat depression. Your doctor can prescribe them for you. They can improve your mood, sleep, appetite and concentration. It may take several weeks for them to help. There are several types of antidepressants. You and your doctor may have to try several before finding what works best for you.

New study may facilitate personalized therapy for depression, other neurological disorders

Depression is the leading cause of disability worldwide, striking as many as one in four women and one in eight men in their lifetime.

5 May 2020

Natural mood regulation is impaired in people with depression, research shows

Periods of lockdown during the COVID-19 situation likely to exacerbate problems with mood regulation, say experts at the University of Oxford.

22 Apr 2020

Nasal spray containing esketamine could provide an effective treatment for depression

Depression and long-term stress have been demonstrated to cause changes in the brain which offer a partial explanation for depressive moods, apathy, memory difficulties and other symptoms commonly associated with depression.

22 Apr 2020

Researchers identify biological mechanism in depressed individuals

University of Illinois at Chicago researchers report that in depressed individuals there are increased amounts of an unmodified structural protein, called tubulin, in lipid rafts - fatty sections of a cell membrane - compared with non-depressed individuals.

22 Apr 2020

Discovery of key protein may lead to more effective treatments for depression

Depression is a common psychiatric disorder and one of the leading causes of disability worldwide. Antidepressants are the first-line treatment for moderate to severe major depressive episodes.

9 Apr 2020

Structural protein may be new target for diagnosis, treatment of depression

Scientists have zeroed in on a structural protein as a new target for the diagnosis and treatment of depression, according to research recently published in JNeurosci.

9 Apr 2020

Risk of depression increases with higher weight, shows study

In an analysis of primary care records of 519,513 UK adults who were overweight or obese between 2000-2016 and followed up until 2019, the incidence of new cases of depression was 92 per 10,000 people per year. The risk of depression also rose with higher weight, according to the Obesity analysis.

8 Apr 2020

Depressive disorders in patients with HIV/AIDS often go unrecognized or untreated

People living with HIV/AIDS are at increased risk of depressive disorders. But all too often, these conditions go unrecognized or untreated, suggests a literature review in the May/June issue of Harvard Review of Psychiatry.

7 Apr 2020

TMS shows promise as treatment for adults with both depression and autism

In a pilot study in adults with autism and depression, transcranial magnetic stimulation, or TMS, was effective in reducing depressive symptoms and had some effects on autistic symptoms, report researchers at the Medical University of South Carolina in Autism Research.

7 Apr 2020

New form of magnetic brain stimulation relieves symptoms of severe depression

A new form of magnetic brain stimulation rapidly relieved symptoms of severe depression in 90% of participants in a small study conducted by researchers at the Stanford University School of Medicine.

7 Apr 2020

New drug can alleviate the side effects of tricyclic antidepressants

About one in five Danes are affected by depression at some point in their lives. The severe depressions may be treated with the so-called 'tricyclic antidepressants', an antidepressant drug that is more effective than the drugs used for mild and moderate depressions.

22 Mar 2020

Odor alters how memories are processed in the brain, research reveals

In a new paper published in Learning and Memory, researchers from Boston University's Center for Systems Neuroscience reveal just how much power scents have in triggering the memory of past experiences--and the potential for odor to be used as a tool to treat memory-related mood disorders.

17 Mar 2020

Researchers uncover novel neurotransmitter system in the brain

Neurotransmitters are chemicals that transmit signals between neurons or from neurons to other cells. They interact with specific receptors found in the brain of humans and animals, controlling a variety of biological processes, e.g. fear, anger, pleasure, memory, energy, appetite and sleep.

5 Mar 2020

Antidepressant shows promise in helping men with recurrent prostate cancer

An antidepressant in use for decades, repurposed to fight prostate cancer, shows promise in helping patients whose disease has returned following surgery or radiation, a pilot study at USC shows.

4 Mar 2020

Autoantibodies can also act as the body's own antidepressants

If the immune system attacks its own body, it can often have devastating consequences: autoantibodies bind to the body's structures, triggering functional disorders.

24 Feb 2020

Using 'mini-brains' to detect harmful neurodevelopmental effects of antidepressant

Researchers at Johns Hopkins Bloomberg School of Public Health have demonstrated the use of stem-cell-derived "mini-brains" to detect harmful side effects of a common drug on the developing brain.

21 Feb 2020

Using a simple model to study how serotonin modulates behavior

In popular experience the story of how serotonin modulates the brain might seem simple: pop an antidepressant, serotonin levels go up, mood improves. But neuroscientists acknowledge how little they know about how the neurotransmitter affects circuits and behavior in the incredibly complex human brain.

20 Feb 2020