Hippocampus News and Research

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The hippocampus is a part of the forebrain, located in the medial temporal lobe. It belongs to the limbic system and plays major roles in short term memory and spatial navigation. Humans and other mammals have two hippocampi, one in each side of the brain.

Changing environment can have long-term, significant effects on the brain

Changes in a person's environment can have long-term, significant effects on the brain, whether it's the inhalation of wildfire smoke or the experience of childhood trauma.

13 Nov 2023

Study shows depression increases disability risk in rheumatoid arthritis sufferers

The interactions between rheumatoid arthritis (RA) and major depressive disorder (MDD).

7 Nov 2023

TIMP2 protein identified as key player in brain plasticity and memory

Researchers explored the molecular and cellular processes regulated by tissue inhibitor of metalloproteinases-2 (TIMP2) in the extracellular matrix (ECM) of the adult brain hippocampus.

6 Nov 2023

Life's hardships rewire the brain: Study pinpoints neural changes from adversity

Research reveals that adverse life experiences heighten amygdala response and diminish prefrontal cortex activity, indicating potential neural mechanisms of psychological vulnerability.

5 Nov 2023

Metabolic increase in the hippocampus is early sign of Alzheimer's disease, study finds

An early phase in the process of developing Alzheimer's disease is a metabolic increase in a part of the brain called the hippocampus, report researchers from Karolinska Institutet in a study published in Molecular Psychiatry.

31 Oct 2023

Spicing up memory: Wasabi found to boost brainpower in seniors

A 12-week study on adults over 60 found that wasabi supplements containing 6-MSITC significantly improved episodic and working memory. While other cognitive domains showed no improvement, the findings suggest that wasabi's anti-inflammatory and anti-oxidant properties may offer new avenues for combating age-related memory decline.

31 Oct 2023

Self-supervised learning models generate brain-like activity patterns

To make our way through the world, our brain must develop an intuitive understanding of the physical world around us, which we then use to interpret sensory information coming into the brain.

30 Oct 2023

Discovery of protein interaction could lead to new schizophrenia treatments

The discovery of a physical interaction between two proteins in brain cells that can be traced in mice to control of movement, anxiety and memory could one day open the door to development of new schizophrenia treatment strategies, researchers say.

26 Oct 2023

Is COVID-19 a risk factor for Alzheimer's disease?

The study explores the interconnected risks between COVID-19 and Alzheimer's Disease (AD), highlighting how SARS-CoV-2 can aggravate AD pathology through neuroinflammation and neurodegeneration. It raises significant concerns about the long-term cognitive implications of COVID-19, especially among those already at risk for AD.

23 Oct 2023

Shedding light on the future of cognitive health in a graying world

Age-related cognitive decline and changes in the brain.

23 Oct 2023

Study explores sex-specific effects in Alzheimers disease pathology

The role of biological sex in the development and progression of Alzheimer's Disease (AD).

19 Oct 2023

Gut microbiota linked to Alzheimer's disease

Researchers have discovered the link between the gut microbiota and Alzheimer's disease.

17 Oct 2023

Gestational dexamethasone exposure impairs learning and memory function across generations

This new article publication from Acta Pharmaceutica Sinica B, discusses how gestational dexamethasone exposure impacts hippocampal excitatory synaptic transmission and learning and memory function with transgenerational effects.

15 Oct 2023

Deep brain stimulation improves memory and promotes neuron growth in Rett mice

A recent study from the lab of Dr. Jianrong Tang, associate professor at Baylor College of Medicine and principal investigator at the Jan and Dan Duncan Neurological Research Institute (Duncan NRI) at Texas Children's Hospital shows that deep brain stimulation (DBS) of a specific brain region results in a significant and sustained improvement of memory in Rett mice.

13 Oct 2023

Could young blood be the key to reversing age-related cognitive decline?

Researchers at the University of Auckland identify platelet factor 4 (PF4) in young blood as a key player in reversing age-related cognitive decline in mice. The study offers a promising avenue for treating dementia-related conditions and enhancing brain function in aging populations.

11 Oct 2023

New AI model can identify neuroanatomical regions vulnerable to age-related changes

The aging brain undergoes structural and cellular changes that can impact function and increase susceptibility to neurodegenerative disorders like Alzheimer's disease.

11 Oct 2023

Research explains the reason behind delay in therapeutic action of antidepressants

SSRI antidepressants normally take a few weeks before any showing mental health benefits, but how come it takes so long? Now a study from a group of clinicians and scientists provides the first human evidence that this is due to physical changes in the brain leading to greater brain plasticity developing over the first few weeks of SSRI intake.

9 Oct 2023