Alzheimer's Disease News and Research

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Alzheimer's disease (AD) is an irreversible, progressive brain disease that slowly destroys memory and thinking skills and, eventually, the ability to carry out the simplest tasks of daily living. In most people with AD, symptoms first appear after age 60. AD is the most common cause of dementia among older people, but it is not a normal part of aging. Dementia refers to a decline in cognitive function that interferes with daily life and activities. AD starts in a region of the brain that affects recent memory, then gradually spreads to other parts of the brain. Although treatment can slow the progression of AD and help manage its symptoms in some people, currently there is no cure for this devastating disease.

Study finds overall pattern of commonality between Huntington's and Parkinson's

A new study strongly suggests that the brains of people who have died of Huntington's disease (HD) and Parkinson's disease (PD) show a similar response to a lifetime of neurodegeneration, despite being two very distinct diseases.

12 Jan 2018

Worsening of anxiety symptoms may be early indicator of Alzheimer's disease

A new study suggests an association between elevated amyloid beta levels and the worsening of anxiety symptoms. The findings support the hypothesis that neuropsychiatric symptoms could represent the early manifestation of Alzheimer's disease in older adults.

12 Jan 2018

Novel polygenic hazard score captures age variations of aggressive prostate cancer

An international team, led by researchers at the University of California San Diego School of Medicine, has developed and validated a genetic tool for predicting age of onset of aggressive prostate cancer, a disease that kills more than 26,000 American men annually.

12 Jan 2018

Insilico Medicine develops new deep-learning based hematological human aging clock

Today, Insilico Medicine, Inc., a Baltimore-based company specializing in the application of artificial intelligence for drug discovery, biomarker development and aging research, announced a publication of a research paper titled "Population-specific biomarkers of human aging: a big data study using South Korean, Canadian and Eastern-European patient populations" in The Journal of Gerontology.

11 Jan 2018

Pfizer to stop Alzheimer’s and Parkinson’s disease research

Pharmaceutical giant Pfizer has announced its intention to stop research and development in areas including Alzheimer’s disease and Parkinson’s disease.

11 Jan 2018

Salk scientists identify molecular target of experimental Alzheimer’s drug

The experimental drug J147 is something of a modern elixir of life; it's been shown to treat Alzheimer's disease and reverse aging in mice and is almost ready for clinical trials in humans.

10 Jan 2018

Alzheimer’s Research UK calls on pharma to continue supporting dementia research

Alzheimer’s Research UK is calling for a recommitment from pharmaceutical companies to continue efforts to fund research into dementia, the leading cause of death in the UK.

10 Jan 2018

Researchers awarded grant to repurpose FDA-approved drugs for treating Alzheimer's patients

Researchers from Case Western Reserve University School of Medicine and collaborators have received a five-year, $2.8 million grant from the National Institute on Aging to identify FDA-approved medications that could be repurposed to treat Alzheimer's disease.

9 Jan 2018

Vanderbilt and Lundbeck collaborate to develop novel approach for treating schizophrenia

Vanderbilt University has signed separate licensing and research collaboration agreements with Lundbeck, a global pharmaceutical company based in Denmark, to develop a novel approach for treating schizophrenia.

9 Jan 2018

Sangamo and Pfizer partner for development of new zinc finger protein gene therapy to treat ALS

Sangamo Therapeutics, Inc. and Pfizer Inc. today announced a collaboration for the development of a potential gene therapy using zinc finger protein transcription factors (ZFP-TFs) to treat amyotrophic lateral sclerosis (ALS) and frontotemporal lobar degeneration (FTLD) linked to mutations of the C9ORF72 gene.

8 Jan 2018

Researchers use Quest MRI to identify earliest signs of Alzheimer's disease in mice

Alzheimer's disease wreaks emotional havoc on patients, who are robbed of their memories, their dignity, and their lives. It's financially devastating as well: care for Alzheimer's patients is predicted to top $1 trillion by about the time children born today are having children of their own.

5 Jan 2018

New study uncovers why sauna bathing provides health benefits

Over the past couple of years, scientists at the University of Eastern Finland have shown that sauna bathing is associated with a variety of health benefits.

5 Jan 2018

Powerful imaging technique sheds light on how the brain responds to vascular injury

Pericytes, a little-understood type of cell on the brain's blood vessels, grow into the empty space left when neighboring pericytes die, report researchers at the Medical University of South Carolina in a January 2nd, 2018 article in Cell Reports.

4 Jan 2018

Testing blood for caffeine levels may aid diagnosis of Parkinson's disease

Testing the level of caffeine in the blood may provide a simple way to aid the diagnosis of Parkinson's disease, according to a study published in the January 3, 2018, online issue of Neurology®, the medical journal of the American Academy of Neurology.

4 Jan 2018

Researchers discover novel genes responsible for Alzheimer's disease

Researchers have identified several new genes responsible for Alzheimer's disease (AD) including those leading to functional and structural changes in the brain and elevated levels of AD proteins in cerebrospinal fluid (CSF).

3 Jan 2018

Advanced live cell imaging reveals brain’s response to blood vessel injury

Live cell imaging and laser beam ablation reveals the damage response of pericytes surrounding blood vessels in the brain.

3 Jan 2018

Diabetes drug holds promise of being developed into new treatment for Alzheimer's

A drug developed for diabetes could be used to treat Alzheimer's after scientists found it "significantly reversed memory loss" in mice through a triple method of action.

2 Jan 2018

Study: Higher dose of anti-seizure drug during pregnancy may increase baby's risk of cleft lip, palate

Taking a higher dose of topiramate during the first three months of pregnancy may increase a baby's risk of cleft lip or cleft palate more than when taking a lower dose, according to a study published in the December 27, 2017, online issue of Neurology, the medical journal of the American Academy of Neurology.

28 Dec 2017

New AAN guideline: Exercising twice a week may improve memory in people with MCI

Exercising twice a week may improve thinking ability and memory in people with mild cognitive impairment (MCI), according to a guideline released by the American Academy of Neurology.

27 Dec 2017

UTA researcher working to show potential link between blast-like trauma and neurological disorders

Efficient communication between neurons in the brain is the key to achieving cognitive function. A University of Texas at Arlington researcher is working to determine how mechanical forces such as blasts or repeated blows to the head could damage neurons and lead to neurological disorders.

22 Dec 2017

Alzheimer's Disease News and Research

Further Reading

Study finds overall pattern of commonality between Huntington's and Parkinson's

Worsening of anxiety symptoms may be early indicator of Alzheimer's disease

Novel polygenic hazard score captures age variations of aggressive prostate cancer

Insilico Medicine develops new deep-learning based hematological human aging clock

Pfizer to stop Alzheimer’s and Parkinson’s disease research

Salk scientists identify molecular target of experimental Alzheimer’s drug

Alzheimer’s Research UK calls on pharma to continue supporting dementia research

Researchers awarded grant to repurpose FDA-approved drugs for treating Alzheimer's patients

Vanderbilt and Lundbeck collaborate to develop novel approach for treating schizophrenia

Sangamo and Pfizer partner for development of new zinc finger protein gene therapy to treat ALS

Researchers use Quest MRI to identify earliest signs of Alzheimer's disease in mice

New study uncovers why sauna bathing provides health benefits

Powerful imaging technique sheds light on how the brain responds to vascular injury

Testing blood for caffeine levels may aid diagnosis of Parkinson's disease

Researchers discover novel genes responsible for Alzheimer's disease

Advanced live cell imaging reveals brain’s response to blood vessel injury

Diabetes drug holds promise of being developed into new treatment for Alzheimer's

Study: Higher dose of anti-seizure drug during pregnancy may increase baby's risk of cleft lip, palate

New AAN guideline: Exercising twice a week may improve memory in people with MCI

UTA researcher working to show potential link between blast-like trauma and neurological disorders

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