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DNA, or deoxyribonucleic acid, is the hereditary material in humans and almost all other organisms. Nearly every cell in a person’s body has the same DNA. Most DNA is located in the cell nucleus (where it is called nuclear DNA), but a small amount of DNA can also be found in the mitochondria (where it is called mitochondrial DNA or mtDNA).

Error-prone DNA replication and repair may lead to cancer in people with inherited BRCA1 mutations

Error-prone DNA replication and repair may lead to mutations and cancer in individuals who inherit a mutant copy of the BRCA1 gene, according to a new study by Weill Cornell Medicine investigators.

15 Nov 2022

Sanford Burnham Prebys researchers receive ACS grants to advance work on difficult-to-treat cancers

Two faculty members from Sanford Burnham Prebys have been awarded grants from the American Cancer Society (ACS), the largest not-for-profit funding body for scientists studying cancer. Associate Professor Cosimo Commisso, Ph.D., and Assistant Professor Svasti Haricharan, Ph.D., each received competitive awards to advance their work on difficult-to-treat cancers.

15 Nov 2022

What are the current challenges and future directions of mRNA nanomedicine?

Researchers presented challenges related to the clinical translation of messenger ribonucleic acid (mRNA) technology, recent innovations and future directions to improve the clinical efficacy of mRNA nanomedicine.

15 Nov 2022

Genetic differences can affect the swimming behavior of sperm cells, study shows

The behavior of sperm cells is due, in part, to the individual DNA make-up of these cells, rather than only to the genetics of males, finds a team of scientists.

15 Nov 2022

Minimally invasive reporter system allows highly sensitive monitoring of RNA production

The better we understand cellular processes such as RNA regulation, the better molecular therapies can be developed.

15 Nov 2022

Behind the Scenes of the Oncology & Precision Medicine Conferences 2022

During the conference, we caught up with some of the speakers to learn more about their work, what they were presenting, and their thoughts about the future of Oncology and Precision Medicine.

15 Nov 2022

Full-metagenome analysis helps identify depressing gut microbe

In a three-year study, researchers from Skoltech, Vavilov Institute of General Genetics of RAS, the Moscow-based Mental-Health Clinic No. 1 Named After N.A. Alexeev and Serbsky Federal Medical Research Centre of Psychiatry and Narcology have examined how gut microbes in patients with a major depressive disorder are different from those in mentally healthy people.

15 Nov 2022

The brain's claustrum behaves more like a high-speed internet router, research finds

Tucked underneath the brain's outer, wrinkly cortex is a deeply mysterious area, known as the claustrum. This region has long been known to exchange signals with much of the cortex, which is responsible for higher reasoning and complex thought.

14 Nov 2022

A novel mRNA-based vaccine candidate against the rabies virus

Scientists have developed a novel mRNA-based vaccine candidate against the rabies virus. The vaccine induces a strong antibody response and exhibits high protective efficacy against lethal rabies infection in mice and dogs. A full report about the vaccine has been published in the Virology Journal.

14 Nov 2022

CLIMB method offers a more efficient way to uncover biologically meaningful changes in genomic data

A new statistical method provides a more efficient way to uncover biologically meaningful changes in genomic data that span multiple conditions - such as cell types or tissues.

14 Nov 2022

New discovery reveals which patients will survive longer after receiving immunotherapy

Patients with head and neck cancer who have more genetic material on chromosome 9 in their cancer cells survive three times longer after receiving immunotherapy than those with less genetic material there, a new study finds.

14 Nov 2022

Unique peptides with anti-cancer potential discovered

A new paper published in Nature Communications presents research on unique peptides with anti-cancer potential.

14 Nov 2022

Researchers provide new insights into the vexing process that makes HIV stealthy

An immune response that likely evolved to help fight infections appears to be the mechanism that drives human immunodeficiency virus (HIV) into a latent state, lurking in cells only to erupt anew, researchers at Duke Health report.

14 Nov 2022

Cancer Research Horizons: The Innovation Engine of Cancer Research UK

Following ELRIG 2022, News-Medical speaks with Cancer Research Horizons, the innovation engine of Cancer Research UK about their efforts to advance the drug discovery sector.

From Cancer Research UK 14 Nov 2022

Sociability in monkeys associated with higher abundance of beneficial gut bacteria

Social connections are essential for good health and wellbeing in social animals, such as ourselves and other primates. There is also increasing evidence that the gut microbiome – through the so-called 'gut-brain axis' – plays a key role in our physical and mental health and that bacteria can be transmitted socially, for example through touch.

11 Nov 2022

Researchers develop a new method to map the spatial evolution of cancers

Researchers developed a genetic clone mapping workflow centered around base-specific in situ sequencing (BaSISS) technology to derive quantitative maps of multiple genetic clones of cancer cells.

11 Nov 2022

The bacteria we breath in everyday

In a recent study published in the journal PNAS, researchers surveyed the global airborne bacterial communities to understand their community structure and biogeographic distribution patterns. In addition, they examined their interactions with Earth’s other microbiomes, particularly surface habitats.

10 Nov 2022

Study shows biological link between muscle weakness and acceleration in biological age

Everyone ages at a different pace. That's why two 50-year-olds, despite living the same number of years, may have different biological ages – meaning that a host of intrinsic and extrinsic factors have caused them to age at varying paces with different levels of risk for disease and early death.

10 Nov 2022

Pitt scientists solve the mystery of how melanoma tumors control their mortality

Scientists at the University of Pittsburgh School of Medicine have discovered the missing puzzle piece in the mystery of how melanoma tumors control their mortality.

10 Nov 2022

Comprehensive whole genome sequencing provides new insight into the 'genomic architecture' of autism

Researchers from The Hospital for Sick Children (SickKids) have uncovered new genes and genetic changes associated with autism spectrum disorder (ASD) in the largest autism whole genome sequencing analysis to date, providing better understanding into the 'genomic architecture' that underlies this disorder.

10 Nov 2022

DNA News and Research

Further Reading

Error-prone DNA replication and repair may lead to cancer in people with inherited BRCA1 mutations

Sanford Burnham Prebys researchers receive ACS grants to advance work on difficult-to-treat cancers

What are the current challenges and future directions of mRNA nanomedicine?

Genetic differences can affect the swimming behavior of sperm cells, study shows

Minimally invasive reporter system allows highly sensitive monitoring of RNA production

Behind the Scenes of the Oncology & Precision Medicine Conferences 2022

Full-metagenome analysis helps identify depressing gut microbe

The brain's claustrum behaves more like a high-speed internet router, research finds

A novel mRNA-based vaccine candidate against the rabies virus

CLIMB method offers a more efficient way to uncover biologically meaningful changes in genomic data

New discovery reveals which patients will survive longer after receiving immunotherapy

Unique peptides with anti-cancer potential discovered

Researchers provide new insights into the vexing process that makes HIV stealthy

Cancer Research Horizons: The Innovation Engine of Cancer Research UK

Sociability in monkeys associated with higher abundance of beneficial gut bacteria

Researchers develop a new method to map the spatial evolution of cancers

The bacteria we breath in everyday

Study shows biological link between muscle weakness and acceleration in biological age

Pitt scientists solve the mystery of how melanoma tumors control their mortality

Comprehensive whole genome sequencing provides new insight into the 'genomic architecture' of autism

Understanding the DNA Damage Response in Innate Immunity eBook

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