Alzheimer's Disease News and Research

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Alzheimer's disease (AD) is an irreversible, progressive brain disease that slowly destroys memory and thinking skills and, eventually, the ability to carry out the simplest tasks of daily living. In most people with AD, symptoms first appear after age 60. AD is the most common cause of dementia among older people, but it is not a normal part of aging. Dementia refers to a decline in cognitive function that interferes with daily life and activities. AD starts in a region of the brain that affects recent memory, then gradually spreads to other parts of the brain. Although treatment can slow the progression of AD and help manage its symptoms in some people, currently there is no cure for this devastating disease.

Research suggests link between heart function and brain region critical for memory processing

Research by a team of Vanderbilt University Medical Center scientists suggests that older people whose hearts pump less blood have blood flow reductions in the temporal lobe regions of the brain, where Alzheimer's pathology first begins.

9 Nov 2017

Early intervention may be crucial to successful treatment of Friedreich's ataxia

New research published today in Disease Models & Mechanisms indicates that early intervention should be a key target in the development of new therapeutics for Friedreich's ataxia, as current treatments may be administered too late to target the disease effectively.

8 Nov 2017

SBP researchers identify new protective function for brain protein genetically linked to Alzheimer's

Researchers at Sanford Burnham Prebys Medical Discovery Institute have identified a new protective function for a brain protein genetically linked to Alzheimer's. The findings, published in the Journal of Experimental Medicine, could inform novel treatment strategies.

7 Nov 2017

Study finds link between increased brain glucose levels and Alzheimer's

A new study published yesterday in Alzheimer's & Dementia: the Journal of the Alzheimer's Association, found a link for the first time between abnormalities in the mechanism of glucose breakdown in the brain and the severity of tangles and amyloid plaques in the brain, as well as the commencement of visible symptoms of Alzheimer's disease.

7 Nov 2017

Popular Alzheimer's drug shows promise in clinical trials for treating patients with sickle cell disease

A popular drug commonly used to treat Alzheimer's disease has shown promise in laboratory and clinical trials for treating patients with sickle cell disease (SCD).

7 Nov 2017

Researchers identify new neuroprotective factor that holds potential to help people with glaucoma

A research team led by scientists at the Krembil Research Institute in Toronto has identified a new neuroprotective factor that has the potential to help people suffering from the common blinding disease glaucoma.

7 Nov 2017

NIH awards grant to test whether anti-inflammatory diet can reduce Alzheimer's disease risk

The National Institutes of Health has awarded Albert Einstein College of Medicine nutrition scientist Yasmin Mossavar-Rahmani, Ph.D., R.D., a five-year, $4 million grant to test whether a diet rich in foods with anti-inflammatory properties can reduce cognitive decline and Alzheimer's disease risk.

6 Nov 2017

Trial indicates blood-plasma infusions for Alzheimer’s patients are safe and may be effective

Researchers from Stanford University School of Medicine have found that giving blood plasma infusions taken from young donors to people with mild-to-moderate Alzheimer’s disease is not only safe and feasible, but may improve recipients’ functional ability and capacity to perform daily tasks.

6 Nov 2017

ACADIA Pharmaceuticals announces results from Phase II study of antipsychotic in Alzheimer's disease psychosis

ACADIA Pharmaceuticals Inc., a biopharmaceutical company focused on the development and commercialization of innovative medicines to address unmet medical needs in central nervous system (CNS) disorders, today announced the presentation of data from the Phase II -019 Study of pimavanserin in Alzheimer's disease psychosis at the 10th Clinical Trials on Alzheimer's Disease meeting in Boston.

3 Nov 2017

Targeting blood-clotting protein may help treat multiple sclerosis and other diseases

Picture a bare wire, without its regular plastic coating. It's exposed to the elements and risks being degraded. And, without insulation, it may not conduct electricity as well as a coated wire. Now, imagine this wire is inside your brain.

2 Nov 2017

Inflammation in mid-life may be linked to brain shrinkage decades later

People who have biomarkers tied to inflammation in their blood in their 40s and 50s may have more brain shrinkage decades later than people without the biomarkers, according to a study published in the November 1, 2017, online issue of Neurology, the medical journal of the American Academy of Neurology. The brain cell loss was found especially in areas of the brain that are affected by Alzheimer's disease.

2 Nov 2017

Maintaining positive friendships may be key to slower memory decline

Maintaining positive, warm and trusting friendships might be the key to a slower decline in memory and cognitive functioning, according to a new Northwestern Medicine study.

2 Nov 2017

Researchers show where in the brain Alzheimer's disease begins

Researchers at Lund University in Sweden have for the first time convincingly shown where in the brain the earliest signs of Alzheimer's occur. The discovery could potentially become significant to future Alzheimer's research while contributing to improved diagnostics.

1 Nov 2017

IUPUI researchers receive grant to design real-world advance care planning program with nursing homes

The National Institute on Aging has awarded two researchers at IUPUI a $400,000 grant to work with nursing homes to design a real-world program to provide systematic, high-quality advance care planning for nursing home patients with Alzheimer's disease and related dementias.

1 Nov 2017

Deep-learning technology reveals anti-aging plant extracts

Life Extension, in collaboration with Insilico Medicine, have employed artificial intelligence to develop a novel dietary supplement of plant extracts that can activate the body's own anti-aging path ways.

31 Oct 2017

Gene therapy prevents age-related learning and memory problems in mice

Researchers from the Institute of Neurosciences at the Universitat Autònoma de Barcelona and the Vall d'Hebron Research Institute are the first to demonstrate that regulation of the brain's Klotho gene using gene therapy protects against age-related learning and memory problems in mice.

31 Oct 2017

Alzheimer's disease could be triggered by breakdowns from other parts of the body

Alzheimer's disease, the leading cause of dementia, has long been assumed to originate in the brain. But research from the University of British Columbia and Chinese scientists indicates that it could be triggered by breakdowns elsewhere in the body.

31 Oct 2017

Researchers discover quirk of cell aging that could help detect late-onset Alzheimer's

Researchers at The University of Texas Health Science Center at Houston School of Dentistry and McGovern Medical School have discovered a previously unknown characteristic of brain-cell aging that could help detect late-onset Alzheimer's disease decades before symptoms begin.

30 Oct 2017

Biogen and Ionis awarded 2017 Prix Galien USA Award for SPINRAZA

Biogen and Ionis have been awarded the prestigious 2017 Prix Galien USA Award for Best Biotechnology Product for SPINRAZA (nusinersen). The Prix Galien USA Award recognizes extraordinary achievement in scientific innovation that improves the state of human health. The award was presented at a ceremony in New York City on October 26, 2017.

30 Oct 2017

Researchers find link between disrupted energy production and late-onset Alzheimer's disease

A team of investigators from McLean Hospital and Harvard Medical School, led by Kai C. Sonntag, MD, PhD, and Bruce M. Cohen, MD, PhD, has found a connection between disrupted energy production and the development of late-onset Alzheimer's disease (LOAD). The findings appear in the current issue of Scientific Reports.

27 Oct 2017

Alzheimer's Disease News and Research

Further Reading

Research suggests link between heart function and brain region critical for memory processing

Early intervention may be crucial to successful treatment of Friedreich's ataxia

SBP researchers identify new protective function for brain protein genetically linked to Alzheimer's

Study finds link between increased brain glucose levels and Alzheimer's

Popular Alzheimer's drug shows promise in clinical trials for treating patients with sickle cell disease

Researchers identify new neuroprotective factor that holds potential to help people with glaucoma

NIH awards grant to test whether anti-inflammatory diet can reduce Alzheimer's disease risk

Trial indicates blood-plasma infusions for Alzheimer’s patients are safe and may be effective

ACADIA Pharmaceuticals announces results from Phase II study of antipsychotic in Alzheimer's disease psychosis

Targeting blood-clotting protein may help treat multiple sclerosis and other diseases

Inflammation in mid-life may be linked to brain shrinkage decades later

Maintaining positive friendships may be key to slower memory decline

Researchers show where in the brain Alzheimer's disease begins

IUPUI researchers receive grant to design real-world advance care planning program with nursing homes

Deep-learning technology reveals anti-aging plant extracts

Gene therapy prevents age-related learning and memory problems in mice

Alzheimer's disease could be triggered by breakdowns from other parts of the body

Researchers discover quirk of cell aging that could help detect late-onset Alzheimer's

Biogen and Ionis awarded 2017 Prix Galien USA Award for SPINRAZA

Researchers find link between disrupted energy production and late-onset Alzheimer's disease

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