Alzheimer's Disease News and Research

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Alzheimer's disease (AD) is an irreversible, progressive brain disease that slowly destroys memory and thinking skills and, eventually, the ability to carry out the simplest tasks of daily living. In most people with AD, symptoms first appear after age 60. AD is the most common cause of dementia among older people, but it is not a normal part of aging. Dementia refers to a decline in cognitive function that interferes with daily life and activities. AD starts in a region of the brain that affects recent memory, then gradually spreads to other parts of the brain. Although treatment can slow the progression of AD and help manage its symptoms in some people, currently there is no cure for this devastating disease.

Nasal spray of gold nanoparticles delivers lithium directly to the brain

In the form of a 'nasal spray', tiny gold particles act as carriers, delivering a treatment directly to the brain: developed by scientists at the Università Cattolica Rome campus/Fondazione Policlinico Universitario A. Gemelli IRCCS, a new nanotechnological device for the treatment and prevention of neuropsychiatric and neurodegenerative diseases.

8 Oct 2025

Largest study of African American brain tissue reveals key Alzheimer gene activity

The prevalence of Alzheimer disease (AD) is approximately two times higher in African Americans (AA) compared to White/European-ancestry (EA) individuals living in the U.S.

8 Oct 2025

Nanotechnology breakthrough reverses Alzheimer’s disease in mice

A research team co-led by the Institute for Bioengineering of Catalonia (IBEC) and West China Hospital Sichuan University (WCHSU), working with partners in the UK, has demonstrated a nanotechnology strategy that reverses Alzheimer's disease in mice.

6 Oct 2025

Investigating cannabidiol's role in combating Alzheimer's-related neuroinflammation

Neuroinflammation damages neurons and can contribute to diseases like Alzheimer's. Cannabidiol (CBD) has anti-inflammatory properties, which suggests that it could combat neuroinflammation in Alzheimer's.

6 Oct 2025

Cell messengers signal amyloid plaque buildup in obese individuals

Obesity has long been acknowledged as a risk factor for a wide range of diseases, but a more precise link between obesity and Alzheimer's disease has remained a mystery – until now.

3 Oct 2025

Study links high neuroinflammation in young people with Down Syndrome to Alzheimer's risk

Down syndrome is associated with accelerated aging. It is estimated that up to 90% of individuals with the condition develop Alzheimer's disease before the age of 70. A study by researchers at the University of São Paulo (USP) in Brazil identified high levels of neuroinflammation in young individuals with Down syndrome, an additional factor explaining the high prevalence of Alzheimer's disease in older people with the condition. The discovery paves the way for strategies to prevent and monitor the disease.

3 Oct 2025

Scientists discover new protein family regulating motility and DNA uptake

Bioengineers at the University of California San Diego have developed a powerful new technology that can map the entire network of RNA-protein interactions inside human cells - an achievement that could offer new strategies for treating diseases ranging from cancer to Alzheimer's.

3 Oct 2025

Thermo Fisher Scientific expands neurodegeneration research capabilities with launch of Olink® Target 48 Neurodegeneration panel

Thermo Fisher Scientific Inc., the world leader in serving science, today announced the launch of the Olink® Target 48 Neurodegeneration panel, a high-performance, targeted proteomics immunoassay panel developed to accelerate discoveries in neurodegenerative disease research.

From Olink®- Part of Thermo Fisher Scientific 3 Oct 2025

Molecular fingerprint predicts physical fitness in older adults

Could a simple blood test reveal how well someone is aging? A team of researchers led by Wolfram Weckwerth from the University of Vienna, Austria, and Nankai University, China, has combined advanced metabolomics with cutting-edge machine learning and a novel network modeling tool to uncover the key molecular processes underlying active aging.

30 Sep 2025

New evidence shows blood-brain barrier remains intact in Alzheimer's mouse model

A team of scientists at Texas Tech University Health Sciences Center (TTUHSC) has published new evidence suggesting that the brain's protective shield - known as the blood-brain barrier (BBB) - remains largely intact in a commonly used mouse model of Alzheimer's disease.

29 Sep 2025

Study shows how early-life epigenetic 'memory' can influence adult brain inflammation

Why do some people remain healthy through childhood yet become more vulnerable to brain disorders such as dementia later in life? A KAIST (President Kwang Hyung Lee) -led team has uncovered a key part of the answer: a developmental 'switch' in astrocytes—the brain's most abundant support cells that shapes how strongly the brain's immune system reacts in adulthood.

25 Sep 2025

Mount Sinai study maps protein networks driving Alzheimer’s disease pathogenesis

A new study led by the Icahn School of Medicine at Mount Sinai offers one of the most comprehensive views yet of how brain cells interact in Alzheimer's disease, mapping protein networks that reveal communication failures and point to new therapeutic opportunities.

25 Sep 2025

COVID-19 linked to long-lasting reductions in smell even without noticeable symptoms

People who suspect that their sense of smell has been dulled after a bout of COVID-19 are likely correct, a new study using an objective, 40-odor test shows. Even those who do not notice any olfactory issues may be impaired.

25 Sep 2025

Healthy habits linked to younger brain age

Your chronological age may say 65, but your brain could be acting a decade younger - or older - depending on your life experiences.

25 Sep 2025

Groundbreaking MRI technique reveals microvascular pulsations in the aging brain

Researchers at the Mark and Mary Stevens Neuroimaging and Informatics Institute (Stevens INI) at the Keck School of Medicine of USC have developed a groundbreaking brain imaging technique that reveals how tiny blood vessels in the brain pulse with each heartbeat-changes that may hold clues to aging and diseases such as Alzheimer's.

25 Sep 2025

New research explores pre-diagnostic indicators of dementia

A new study from Finland shows that low labor market participation for non-retirement related reasons may be an early indicator of dementia already years before the first evident symptoms occur. The study also identified other social markers that may be indicative of dementia up to ten years before a diagnosis of Alzheimer's disease, frontotemporal dementia or vascular dementia.

24 Sep 2025

Scientists map step-by-step activation of brain receptors

When it comes to brain proteins, small changes can make a dramatic difference. Researchers studying NMDA (N-methyl-D-aspartate) receptors, which are essential for learning, memory and moment-by-moment consciousness, know that even slight changes in their activity level can mean the difference between normal function and serious neurological disorders.

24 Sep 2025

Influenza infection in pregnant mice linked to fetal brain exposure

A new study from the University of Illinois Urbana-Champaign shows, for the first time, that severe flu infection in pregnant mice leads to a breakdown in placental and brain barriers, leading to the accumulation of potentially harmful molecules in the fetal brain.

24 Sep 2025

University of Utah launches landmark study linking blood pressure and brain health

In six massive laboratory freezers at the University of Utah, nearly 40,000 blood samples wait in frozen stasis.

24 Sep 2025

Innovative technique could reveal Alzheimer’s before symptoms appear

NAU researchers are experimenting with new technology that could help medical providers easily detect Alzheimer's disease early and prevent its advance.

24 Sep 2025

Alzheimer's Disease News and Research

Further Reading

Nasal spray of gold nanoparticles delivers lithium directly to the brain

Largest study of African American brain tissue reveals key Alzheimer gene activity

Nanotechnology breakthrough reverses Alzheimer’s disease in mice

Investigating cannabidiol's role in combating Alzheimer's-related neuroinflammation

Cell messengers signal amyloid plaque buildup in obese individuals

Study links high neuroinflammation in young people with Down Syndrome to Alzheimer's risk

Scientists discover new protein family regulating motility and DNA uptake

Thermo Fisher Scientific expands neurodegeneration research capabilities with launch of Olink® Target 48 Neurodegeneration panel

Molecular fingerprint predicts physical fitness in older adults

New evidence shows blood-brain barrier remains intact in Alzheimer's mouse model

Study shows how early-life epigenetic 'memory' can influence adult brain inflammation

Mount Sinai study maps protein networks driving Alzheimer’s disease pathogenesis

COVID-19 linked to long-lasting reductions in smell even without noticeable symptoms

Healthy habits linked to younger brain age

Groundbreaking MRI technique reveals microvascular pulsations in the aging brain

New research explores pre-diagnostic indicators of dementia

Scientists map step-by-step activation of brain receptors

Influenza infection in pregnant mice linked to fetal brain exposure

University of Utah launches landmark study linking blood pressure and brain health

Innovative technique could reveal Alzheimer’s before symptoms appear

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