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New insights reveal how Candida albicans settle and persist in the gut

About 80% of people have the fungus Candida albicans in their gut. Although most of the time it persists unnoticed for years causing no health problems, C. albicans can turn into a dangerous microbe that causes serious diseases in many organs, including the urinary tract, lungs and brain.

30 Jul 2025

PD-1 helps guide immune memory cells to the skin early during infection

Weill Cornell Medicine researchers have discovered that PD-1—a molecule best known for putting the brakes on immune cells—also plays a critical role in helping T cells become long-term immune defenders in the skin.

30 Jul 2025

Immune cells migrate from the gut to breast during pregnancy and lactation

Of the 3.6 million babies born in the United States each year, around 80 percent begin breastfeeding in their first month of life.

30 Jul 2025

Plant-based agent inhibits key protein to reduce bronchial thickening

A plant-based agent inhibits a protein that, among other things, is responsible for the dreaded thickening of the bronchial wall.

29 Jul 2025

Dental floss may offer a novel vaccine delivery method

Researchers have demonstrated a novel vaccine delivery method in an animal model, using dental floss to introduce vaccine via the tissue between the teeth and gums.

28 Jul 2025

New study uncovers how prior obesity impacts viral consequences

A study comparing the effects of SARS-CoV-2 infection in lean and obese primates found different long-term consequences of the virus depending on prior obesity and metabolic disease. The results, which also highlighted how widespread long COVID symptoms are in animals, were published July 24th in the open-access journal PLOS Pathogens by Charles Roberts of Oregon Health & Science University, USA, and colleagues.

25 Jul 2025

Blocking nutrient scavenging weakens pancreatic tumor defenses

Cancer cells and tumors do not exist in a vacuum. Far from the isolation and self-sufficiency of the fictional Wakanda, tumors develop in and alter the nearby milieu of immune cells, connective tissue, blood vessels and a sea of proteins and carbohydrates that provide structure and other supportive functions.

24 Jul 2025

Standard DNA tests miss most cases of NUT carcinoma

The diagnosis of a suspected lung, head, and neck cancer called NUT carcinoma should include additional testing capable of detecting gene fusions that are definitive markers of the disease, according to a study by Dana-Farber Cancer Institute investigators.

24 Jul 2025

Long-term air pollution exposure triggers allergic immune responses in the lungs

Air pollution is a global health concern, with over 90% of the world's population breathing air that exceeds World Health Organization safety standards.

23 Jul 2025

New 3D tissue model offers hope for scleroderma treatment

For the 300,000 Americans living with the immune disease scleroderma, better treatments can't come soon enough. The rare and sometimes fatal illness stiffens and scars tissue in organs like the lungs, liver, and kidneys, as well as skin.

22 Jul 2025

Muscle loss from GLP-1 drugs could undermine long-term health

Popular GLP-1 drugs help many people drop tremendous amounts of weight, but the drugs fail to provide a key improvement in heart and lung function essential for long-term good health, University of Virginia experts warn in a new paper.

21 Jul 2025

Parental cholesterol predicts asthma severity in children

Parental metabolic health influences childhood asthma severity, with paternal cholesterol showing modest protective effects against exacerbating symptoms.

18 Jul 2025

Chronic venous insufficiency linked to increased cardiovascular disease and mortality risk

In light of reports from the White House that President Donald J. Trump has been diagnosed with Chronic Venous Insufficiency (CVI), the American Heart Association is sharing important information on the condition and its association with cardiovascular risk factors, disease and increased risk of death.

18 Jul 2025

PAR1 protein found to boost lung fluid drainage during injury

A protein called PAR1 helps lymphatic vessels structurally transform to boost fluid drainage and support healing when the lungs are injured according to researchers from Weill Cornell Medicine.

18 Jul 2025

Discovery of hybrid Aspergillus species with antifungal resistance in Japan

Aspergillus is a fungus that is commonly found in the environment, both indoors and outdoors. This fungus species can cause aspergillosis-a respiratory infection affecting the lungs. A. fumigatus, A. nidulans, and A. niger are some of the common species within the Aspergillus genus that cause aspergillosis.

17 Jul 2025

New method enables recovery of hearts from deceased organ donors after circulatory death

Vanderbilt University Medical Center researchers have developed a groundbreaking new method for the recovery of hearts from deceased organ donors after circulatory death (DCD).

16 Jul 2025

New micro physiological system emulates different regions of the human lung

Respiratory infections such as COVID-19 have been responsible for numerous pandemics and have placed a substantial burden on healthcare systems.

16 Jul 2025

Qureight analyze of Insilico Medicine's Phase IIa rentosertib data support preliminary efficacy results and future trial expansion

Qureight, a techbio company accelerating drug development using its proprietary deep-learning image biomarkers and clinical data analytics platform, today announced the first results from a collaboration with Insilico Medicine ("Insilico"), a clinical-stage biotechnology company driven by generative AI, focused on rentosertib (ISM001-055), a novel TNIK inhibitor discovered using Insilico's generative AI approach, in development for the treatment of IPF.

16 Jul 2025

TB bacteria can play dead to outlast the immune response, study reveals

A vaccine protects more than 100 million infants each year from severe tuberculosis (TB), including the fatal brain swelling it can cause in babies and toddlers.

15 Jul 2025

Blocking Epac1 protein slows lung fibrosis in preclinical models

Researchers at the Icahn School of Medicine at Mount Sinai and collaborators have identified a previously overlooked protein, Epac1, as a key driver of idiopathic pulmonary fibrosis (IPF), a chronic and progressive lung-scarring disease.

15 Jul 2025