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Traumatic brain injury disrupts brain drainage and accelerates Alzheimer’s risk

University of Virginia School of Medicine researchers have uncovered how and why traumatic brain injury (TBI) increases the risk for Alzheimer's disease, and their work suggests a potential way to prevent that increased risk.

16 Dec 2025

Neuron structure variations impact sensory information processing in mice

Closely related subtypes of dopamine-releasing neurons may play entirely separate roles in processing sensory information, depending on their physical structure.

16 Dec 2025

Tau biology expands beyond microtubules to neurodegeneration, metabolism and mental illness

An Thought Leaders Invited Review published today in Genomic Psychiatry by Dr. Peng Lei and colleagues presents a sweeping synthesis of tau protein research that fundamentally reframes our understanding of this molecule's dual identity.

16 Dec 2025

GDF3 protein sustains harmful inflammation in aging immune cells

As people age, their bodies develop a dysfunctional immune system, which can leave older adults more susceptible to conditions like sepsis.

15 Dec 2025

Six midlife depressive symptoms linked to dementia decades later

Six particular depressive symptoms when experienced in midlife predict dementia risk more than two decades later, finds a new study led by University College London (UCL) researchers.

15 Dec 2025

COVID-19 could leave a measurable imprint on the brain

COVID-19 does not just affect the respiratory system, but also significantly alters the brain in people who have fully recovered from the infectious disease, highlighting the long-term neurological impact of the virus.

15 Dec 2025

Hypertrophic chondrocytes play a crucial role in bone growth and repair

Normal, regulated growth of skeletal bones is a crucial part of the growth of mammals. This is a complex process involving the growth of cartilaginous cells or chondrocytes, their transformation into bone-building cells or osteoblasts, and the formation of new blood vessels to supply the newly formed bone tissue.

13 Dec 2025

Etomidate proves safer than ketamine for emergency intubations

Doctors treating seriously ill patients in an emergency setting may want to give the sedative etomidate, rather than ketamine, while placing a breathing tube, according to a randomized trial published Dec. 9 in the New England Journal of Medicine.

12 Dec 2025

Indiana University physician joins FDA panel on male hormone therapy

Helen Bernie, DO, MPH, assistant professor of urology at Indiana University School of Medicine, will participate in an expert panel on testosterone replacement therapy and men's health to be held Wednesday, Dec. 10, by the U.S. Food and Drug Administration. Bernie's role on the panel is that of a clinical expert on men's reproductive health, which is the focus of both her practice and academic research.

12 Dec 2025

Researchers identify enzyme linked to myelin damage and neurodegenerative conditions

Researchers at Oregon Health & Science University have identified a type of enzyme with a complicated name - cell migration inducing and hyaluronan-binding protein, or CEMIP - is associated with disorders ranging from multiple sclerosis to stroke to neurodegenerative conditions like Alzheimer's disease.

11 Dec 2025

AI-based tool may help personalize the treatment of patients with reduced coronary blood flow

Reduced coronary blood flow, measured with an artificial intelligence-based imaging tool, predicted future cardiovascular events in patients with suspected stable coronary artery disease.

11 Dec 2025

Australian researchers pinpoint specific genetic changes linked to severe AMD

Australian researchers have for the first time pinpointed specific genetic changes that increase the risk of severe, sight-threatening forms of age-related macular degeneration (AMD).

9 Dec 2025

Genome-edited immune cell therapy shows promise for treating aggressive blood cancer

A groundbreaking new treatment using genome-edited immune cells, developed by scientists at UCL (University College London) and Great Ormond Street Hospital (GOSH), has shown promising results in helping children and adults fight a rare and aggressive form of blood cancer called T-cell acute lymphoblastic leukemia (T-ALL).

8 Dec 2025

Study reveals new genetic insights into reticular pseudodrusen in people with AMD

A study funded in part by the National Institutes of Health (NIH) has revealed important insights into the genetics of deposits in the eye, known as reticular pseudodrusen (RPD), that are linked to greater risk of vision loss among people with age-related macular degeneration (AMD).

8 Dec 2025

Sleep may hold the key to staying active

Getting enough sleep and staying active are two of the most important things we can do for our health, but new research shows that most people struggle to achieve both, and that sleep may hold the key to moving more.

8 Dec 2025

ECU researchers develop new tool to evaluate fear avoidance behavior after concussion

Researchers from Edith Cowan University (ECU) have developed a new tool to evaluate fear avoidance behavior following a concussion.

4 Dec 2025

Understanding how adult brains adapt to challenge and change

In a revelatory Genomic Press Interview published today in Brain Medicine, Dr. Paul Lucassen, full professor at the University of Amsterdam and leader of the Brain Plasticity group, shares his scientific journey that helped transform our understanding of how adult brains adapt to challenge and change.

4 Dec 2025

Retinal organoids provide a powerful tool to diagnose and study Leber congenital amaurosis

Leber Congenital Amaurosis (LCA) is an inherited retinal disease leading to severe vision impairment from early infancy, affecting 2-3 out of every 100,000 newborns. LCA is caused by variants in certain genes from which proteins essential for retinal cell function and survival are made.

3 Dec 2025

New rapid test distinguishes real HIV infections from vaccine-related false positives

Since the human immunodeficiency virus (HIV) was identified in 1983, roughly 91.4 million people around the world have contracted the virus and an additional 44.1 million have died from related causes.

3 Dec 2025

NeuMap unveils the hidden architecture and life-long patterns of human neutrophils

Neutrophils are the most abundant immune cells in the body and the first to respond to infection or tissue damage.

3 Dec 2025

Medical Research News and Research

Traumatic brain injury disrupts brain drainage and accelerates Alzheimer’s risk

Neuron structure variations impact sensory information processing in mice

Tau biology expands beyond microtubules to neurodegeneration, metabolism and mental illness

GDF3 protein sustains harmful inflammation in aging immune cells

Six midlife depressive symptoms linked to dementia decades later

COVID-19 could leave a measurable imprint on the brain

Hypertrophic chondrocytes play a crucial role in bone growth and repair

Etomidate proves safer than ketamine for emergency intubations

Indiana University physician joins FDA panel on male hormone therapy

Researchers identify enzyme linked to myelin damage and neurodegenerative conditions

AI-based tool may help personalize the treatment of patients with reduced coronary blood flow

Australian researchers pinpoint specific genetic changes linked to severe AMD

Genome-edited immune cell therapy shows promise for treating aggressive blood cancer

Study reveals new genetic insights into reticular pseudodrusen in people with AMD

Sleep may hold the key to staying active

ECU researchers develop new tool to evaluate fear avoidance behavior after concussion

Understanding how adult brains adapt to challenge and change

Retinal organoids provide a powerful tool to diagnose and study Leber congenital amaurosis

New rapid test distinguishes real HIV infections from vaccine-related false positives

NeuMap unveils the hidden architecture and life-long patterns of human neutrophils

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