immunity News and Research

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Organ-on-a-chip system reveals how aging weakens vaccine-driven anti-cancer immunity

Dr. Vadim Jucaud's lab at the Terasaki Institute has introduced a new organ-on-a-chip platform that recapitulates age-dependent immune responses, offering a more accurate testing bed for evaluating cancer vaccine performance in older adults, the population most affected by cancer and often overlooked in traditional preclinical testing.

4 Dec 2025

Single-dose dengue vaccine will benefit populations in hard-to-reach regions

A world-first single-dose vaccine against the dengue virus, manufactured and approved for use in Brazil, will especially benefit populations in hard-to-reach regions of the country such as the Amazon, say disease specialists.

4 Dec 2025

Injectable scaffold vaccine shows strong protection against implant-related MRSA

Research reveals that silica scaffolds can train the immune system against S. aureus, offering a novel approach to prevent orthopedic device infections.

4 Dec 2025

NeuMap unveils the hidden architecture and life-long patterns of human neutrophils

Neutrophils are the most abundant immune cells in the body and the first to respond to infection or tissue damage.

3 Dec 2025

How tick saliva reprograms the skin’s immune defenses

A research team led by the Medical University of Vienna has gained new insights into how ticks influence the human immune system in order to introduce pathogens.

2 Dec 2025

RFK Jr. wants to delay the hepatitis B vaccine. Here’s what parents need to know.

Working out of a tribal-owned hospital in Anchorage, Alaska, liver specialist Brian McMahon has spent decades treating the long shadow of hepatitis B. Before a vaccine became available in the 1980s, he saw the virus claim young lives in western Alaskan communities with stunning speed.

2 Dec 2025

Generative AI aids discovery of ISM3830's novel scaffold

Casitas B-lineage lymphoma-b (CBLB) is an E3 ubiquitin–protein ligase that functions as an intracellular checkpoint and master negative regulator of T‑cell and natural killer (NK) cell activation, playing a central role in modulating T-cell activation and immune tolerance, and its inhibition enhances T cells and NK cells function, also provides a strategy for the function restoration of exhausted T cells.

1 Dec 2025

Innate immunity and metabolic stress drive a unique form of cell death

In several disease conditions, including infections and cancers, innate immune activation and nutrient scarcity occur together.

1 Dec 2025

Why green tea delivers the strongest health benefits

This review examines tea's health effects, highlighting green tea's benefits for heart health and cognition, and warns about risks in processed tea products.

1 Dec 2025

Measles deaths plummet but infections surge worldwide

Global immunization efforts have led to an 88% drop in measles deaths between 2000 and 2024, according to a new report from the World Health Organization (WHO). Nearly 59 million lives have been saved by the measles vaccine since 2000.

29 Nov 2025

Early-infancy infection with RSV increases the risk of developing childhood asthma

Belgian scientists from VIB and Ghent University (UGent), together with Danish collaborators, have uncovered compelling evidence that early-infancy infection with respiratory syncytial virus (RSV) significantly increases the risk of developing childhood asthma-especially in children with a family history of allergy or asthma.

29 Nov 2025

How the gut microbiome links obesity to colorectal cancer

The gut microbiome serves as both a biomarker and therapeutic target in diseases like obesity, metabolic syndrome, and colorectal cancer.

28 Nov 2025

Tattoo ink alters immune cells and weakens some vaccine responses

New research shows tattoo pigments migrate to lymph nodes, causing inflammation and altering immune responses to vaccines, with potential health risks.

27 Nov 2025

New study links inherited mitochondrial DNA mutation to disrupted immune balance

Scientists have discovered how a mitochondrial mutation rewires immune function in a model of inherited primary mitochondrial disorders, which often lead to severe disability and death.

26 Nov 2025

Gut nervous system controls intestinal barrier and allergy risk

An international research team led by scientists from Bern and Charité - Universitätsmedizin Berlin has identified a previously unknown function of the intestinal nervous system.

25 Nov 2025

Unraveling the mycobiome's role in cancer

A growing body of evidence indicates that the microbiome within the gut and tumors significantly influences cancer initiation, progression, and treatment response.

25 Nov 2025

Gut neurons control immunity attack or repair

Beneath the surface of your gut lies a vast network of neurons—as many as in your spinal cord. New research from the Champalimaud Foundation (CF) in Lisbon shows that in mice this "second brain" helps decide whether the immune system should go into attack mode or start repairing tissue.

24 Nov 2025

Single-cell RNA sequencing uncovers diverse CD4⁺ T-cell subtypes in pediatric lupus

Detailed mapping of CD4⁺ T cells from children with systemic lupus erythematosus (SLE) has revealed distinct immune cell subsets with likely roles in disease pathogenesis, according to a study led by Weill Cornell Medicine investigators.

24 Nov 2025

Study finds GLP-1 drugs improve strength and reverse aging biology in mice

Researchers showed that GLP-1 receptor agonism counteracts aging across multiple organs in mice, improving strength and reversing molecular aging signatures without meaningful effects on body weight. These benefits depended largely on hypothalamic GLP-1R signaling and closely mirrored the anti-aging patterns produced by rapamycin.

23 Nov 2025

Intranasal nanomedicine shows promise against glioblastoma

Researchers at Washington University School of Medicine in St. Louis, along with collaborators at Northwestern University, have developed a noninvasive approach to treat one of the most aggressive and deadly brain cancers.

22 Nov 2025

immunity News and Research

Organ-on-a-chip system reveals how aging weakens vaccine-driven anti-cancer immunity

Single-dose dengue vaccine will benefit populations in hard-to-reach regions

Injectable scaffold vaccine shows strong protection against implant-related MRSA

NeuMap unveils the hidden architecture and life-long patterns of human neutrophils

How tick saliva reprograms the skin’s immune defenses

RFK Jr. wants to delay the hepatitis B vaccine. Here’s what parents need to know.

Generative AI aids discovery of ISM3830's novel scaffold

Innate immunity and metabolic stress drive a unique form of cell death

Why green tea delivers the strongest health benefits

Measles deaths plummet but infections surge worldwide

Early-infancy infection with RSV increases the risk of developing childhood asthma

How the gut microbiome links obesity to colorectal cancer

Tattoo ink alters immune cells and weakens some vaccine responses

New study links inherited mitochondrial DNA mutation to disrupted immune balance

Gut nervous system controls intestinal barrier and allergy risk

Unraveling the mycobiome's role in cancer

Gut neurons control immunity attack or repair

Single-cell RNA sequencing uncovers diverse CD4⁺ T-cell subtypes in pediatric lupus

Study finds GLP-1 drugs improve strength and reverse aging biology in mice

Intranasal nanomedicine shows promise against glioblastoma

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