Pathology News and Research

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Pathology is the study and diagnosis of disease through examination of organs, tissues, bodily fluids, and whole bodies (autopsies). The term also encompasses the related scientific study of disease processes, called General pathology. Medical pathology is divided in two main branches, Anatomical pathology and Clinical pathology. Veterinary pathology is concerned with animal disease whereas Phytopathology is the study of plant diseases.

Mitochondrial DNA may have strong influence on cellular metabolism and disease susceptibility

About 1.5 billion years ago, tiny visitors came to live inside the cells that later evolved into all plant and animal life -- including humans.

9 Nov 2018

WHO revise treatment guidelines of lymphatic filariasis due to CWRU-led study

Researchers from Case Western Reserve University School of Medicine have shown that a single "cocktail" of three pill-based anti-parasite medications is significantly more effective at killing microscopic larval worms in people diagnosed with lymphatic filariasis, commonly known as elephantiasis, than other standard two-drug combinations previously used in the global effort to eliminate this infectious disease.

9 Nov 2018

Studying sensory neurons could provide new insights to treat ALS

Virginia Tech Carilion Research Institute scientists have shown that mutations in specific genes that destroy motor neurons and thereby cause the devastating effects of amyotrophic lateral sclerosis-- also known as ALS or Lou Gehrig's disease -- also attack sensory neurons.

9 Nov 2018

Researchers reveal link between autoimmune and cardiovascular disease in mice

People with autoimmune diseases such as psoriasis, lupus and rheumatoid arthritis are at high risk of developing cardiovascular disease, even though none of these conditions seem to target the cardiovascular system directly.

8 Nov 2018

Case Western Reserve School of Medicine receives NIH grant for undergraduate cancer research

Case Western Reserve University School of Medicine is preparing and inspiring a new generation of cancer investigators through Cancer-focused Summer Undergraduate Research.

7 Nov 2018

Accelerating adoption of artificial intelligence-powered image search and whole slide scanning workflows

Huron announces it will accelerate the deployment of digital pathology workflows in hospitals and research/educational facilities.

From Huron Technologies 6 Nov 2018

Researchers identify genetic variation that may influence severity of CTE disease

Researchers have identified a genetic variation that may influence chronic traumatic encephalopathy disease severity.

5 Nov 2018

Fluorescent marker helps surgeons to distinguish aggressive cancer cells from other cells

A chemical that highlights tumor cells has been used by surgeons to help spot and safely remove brain cancer in a trial presented at the 2018 NCRI Cancer Conference.

5 Nov 2018

Genetic inhibition of SARM1 prevents axonal degeneration in nervous systems

Disarm Therapeutics, a biotechnology company creating a new class of disease-modifying therapeutics for patients with axonal degeneration, a central driver of neurological disease, today announced data demonstrating that genetic inhibition of SARM1 prevents axonal degeneration in the central, ocular and peripheral nervous systems.

5 Nov 2018

Huron Digital Pathology partners with MBF Bioscience to help accelerate life science research

Huron and MBF Bioscience announce partnership to offer customized models of Huron’s TissueScope whole slide scanners integrated with MBF’s Stereo Investigator.

From Huron Technologies 2 Nov 2018

Wild monkeys in the Americas transmit Zika virus to humans via mosquitoes, reports study

A collaborative group of researchers from The University of Texas Medical Branch at Galveston and the Faculty of Medicine of Sao Jose do Rio in Brazil is the first to report that wild monkeys in the Americas are transmitting the Zika virus to humans via mosquitoes, making complete eradication of the virus in the Americas very unlikely.

2 Nov 2018

Researchers find a class of drug that could be promising treatment for uveitis

Ocular inflammation uveitis is a serious disease that can destroy eye tissue and cause irreversible blindness.

2 Nov 2018

Scientists identify more aggressive chemotherapy treatment for childhood brain cancer

Scientists led by Newcastle University have been able to identify the group of children needing more intensive, aggressive chemotherapy treatment for the most common form of brain cancer.

2 Nov 2018

MCG selected as designated laboratory for NCI-MATCH trial

The Georgia Esoteric and Molecular Laboratory at the Medical College of Georgia at Augusta University has been selected as a designated laboratory for the National Cancer Institute's Molecular Analysis for Therapy Choice, or MATCH trial, which is assessing the effectiveness of targeting cancer-causing gene changes rather than cancer type.

1 Nov 2018

4TECH successfully completes first two implantations of TriCinch Coil tricuspid valve repair system

4TECH Inc., a leader in the field of transcatheter tricuspid valve repair, initiated its U.S. Early Feasibility Study, following receipt of approval from the U.S. Food and Drug Administration, with the successful first two implantations of the TriCinch Coil System at Piedmont Heart Hospital, Atlanta, Georgia, by Dr. Christopher Meduri, Dr. Vivek Rajagopal and Dr. Mani Vannan.

1 Nov 2018

Unraveling a rare genetic mutation related to growth disorders

What would happen if you suddenly stopped growing at age 12 or 13? Solving genetic growth mysteries and scheduling regular appointments with pediatric endocrinologists is atypical for most parents and pediatricians.

1 Nov 2018

Cytokine levels could predict autoimmune reactions to cancer immunotherapy

The development of immunotherapy, which mobilizes the body's own immune system to destroy cancer cells, is one of the greatest advances in cancer treatment, but immunotherapy can cause harm to healthy tissue in some patients.

31 Oct 2018

Pain sensitization linked to increased risk for persistent knee pain

Becoming more sensitive to pain, or pain sensitization, is an important risk factor for developing persistent knee pain in osteoarthritis, according to a new study by researchers from the Université de Montréal School of Rehabilitation and Hôpital Maisonneuve Rosemont Research Centre in collaboration with researchers at Boston University School of Medicine.

31 Oct 2018

Scientists identify 'skeleton key' for congenital kidney disease research

Scientists in Japan have found a 'skeleton key' for congenital kidney disease research. Using iPS cells generated from the skin cells of a patient with a nephrin mutation, Kumamoto University scientists have successfully developed kidney tissue that exhibits the early stages of congenital kidney disease.

31 Oct 2018

Genetic defect linked to ALS causes sugar-starved cells to overproduce lipids

A genetic defect tied to a variety of neurodegenerative diseases and mental illnesses changes how cells starved of sugar metabolize fatty compounds known as lipids, a new study led by researchers from the Johns Hopkins Bloomberg School of Public Health shows.

31 Oct 2018

Pathology News and Research

Further Reading

Mitochondrial DNA may have strong influence on cellular metabolism and disease susceptibility

WHO revise treatment guidelines of lymphatic filariasis due to CWRU-led study

Studying sensory neurons could provide new insights to treat ALS

Researchers reveal link between autoimmune and cardiovascular disease in mice

Case Western Reserve School of Medicine receives NIH grant for undergraduate cancer research

Accelerating adoption of artificial intelligence-powered image search and whole slide scanning workflows

Researchers identify genetic variation that may influence severity of CTE disease

Fluorescent marker helps surgeons to distinguish aggressive cancer cells from other cells

Genetic inhibition of SARM1 prevents axonal degeneration in nervous systems

Huron Digital Pathology partners with MBF Bioscience to help accelerate life science research

Wild monkeys in the Americas transmit Zika virus to humans via mosquitoes, reports study

Researchers find a class of drug that could be promising treatment for uveitis

Scientists identify more aggressive chemotherapy treatment for childhood brain cancer

MCG selected as designated laboratory for NCI-MATCH trial

4TECH successfully completes first two implantations of TriCinch Coil tricuspid valve repair system

Unraveling a rare genetic mutation related to growth disorders

Cytokine levels could predict autoimmune reactions to cancer immunotherapy

Pain sensitization linked to increased risk for persistent knee pain

Scientists identify 'skeleton key' for congenital kidney disease research

Genetic defect linked to ALS causes sugar-starved cells to overproduce lipids

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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