Tumor News and Research

RSS

Study details the “immunometabolic editing” mechanism of tumor evolution

A Ludwig Cancer Research study has discovered that the immune system's surveillance of cancer can itself induce metabolic adaptations in the cells of early-stage tumors that simultaneously promote their growth and equip them to suppress lethal immune responses.

5 Jan 2023

Free spike proteins in the blood appear to play a role in myocarditis post-COVID mRNA vaccine

A recent study published in the journal Circulation examines the immunological picture in this scenario, looking for clues to the etiology of this rare and potentially serious complication.

5 Jan 2023

Immune system B-cells may be better in predicting HER2-positive breast cancer treatment response

Researchers at UNC Lineberger Comprehensive Cancer Center and colleagues have found that measuring activation of immune-system B cells may be better than measuring either T-cell activation or the total number of immune cells in and around a tumor, called tumor-infiltrating lymphocytes (TILs), in predicting whether HER2-positive breast cancer responds to treatment.

5 Jan 2023

Mediterranean diet may benefit health in part by incorporating moderate wine consumption

Many public health warnings have been issued against alcohol consumption, even in small quantities, though the evidence for such strict limits is controversial. The current study, published in the MDPI journal Nutrients, is a narrative review focused on clearing up some of the confusion associated with alcoholic drinks.

4 Jan 2023

Study shows the potential of a game-changing drug to treat upper urinary tract urothelial cancers

A team from 15 U.S. medical centers led by UT Southwestern Simmons Cancer Center researchers has performed the first analysis of a potentially game-changing drug to treat upper urinary tract urothelial cancers.

4 Jan 2023

New dual-action, cancer-killing vaccine tested in an advanced mouse model of glioblastoma

Scientists are harnessing a new way to turn cancer cells into potent, anti-cancer agents. In the latest work from the lab of Khalid Shah, MS, PhD, at Brigham and Women's Hospital, a founding member of the Mass General Brigham healthcare system, investigators have developed a new cell therapy approach to eliminate established tumors and induce long-term immunity, training the immune system so that it can prevent cancer from recurring.

4 Jan 2023

Distinct genomic patterns of malignant peripheral nerve sheath tumors may help with early diagnosis

Neurofibromatosis type 1 (NF1) is a common genetic condition, affecting 1 in 3000 individuals, and people with NF1 are at greater risk of developing a rare, aggressive form of cancer.

4 Jan 2023

The relationship between metabolic disease and alternations in lipid homeostasis

Researchers assessed the function of lipids in metabolic diseases.

4 Jan 2023

Precise 3D imaging can help measure radiation during cancer treatment

Radiation, used to treat half of all cancer patients, can be measured during treatment for the first time with precise 3D imaging developed at the University of Michigan.

3 Jan 2023

Technical advances expand the application of mass spectrometry imaging in pharmaceutical research

Announcing a new publication for Acta Materia Medica journal. Mass spectrometry imaging (MSI) has been shown to be a valuable tool through nearly every stage of the preclinical drug research and development (R&D) pipeline, and even to the early phase of clinical pharmaceutical evaluation.

3 Jan 2023

Novel triple immunotherapy combination improves anti-tumor responses in preclinical models of pancreatic cancer

Pancreatic ductal adenocarcinoma (PDAC) is a highly lethal malignancy with poor prognosis and limited treatment options.

3 Jan 2023

The role of exosomes in osteosarcoma diagnosis, prognosis, and therapeutics

Announcing a new publication for Acta Materia Medica journal. Osteosarcoma, a primary malignant tumor of the skeleton, has a morbidity of 2.5 per 1 million people.

3 Jan 2023

Researchers identify novel gene mechanism in most aggressive kidney cancers

In a new study from the Johns Hopkins Kimmel Cancer Center, researchers described a novel mechanism of tumor formation in kidney cancers driven by overexpression of the mechanistic target of rapamycin complex 1 (mTORC1) signaling pathway with loss of the tuberous sclerosis complex (TSC) tumor suppressor gene.

3 Jan 2023

Bacterial outer membrane vesicles: utility as vaccines and novel engineering approaches

Scientists have described the utility of gram-negative bacteria-derived outer membrane vesicles as vaccines and methods to expand their applications.

3 Jan 2023

Weighing risks of a major surgery: 7 questions older Americans should ask their surgeon

Larry McMahon, who turns 80 this month, is weighing whether to undergo a major surgery. Over the past five years, his back pain has intensified. Physical therapy, muscle relaxants, and injections aren't offering relief.

3 Jan 2023

Why do some people develop persistent lung sequelae after severe COVID-19?

Clinical presentation following severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) ranges from mild self-limiting illness to severe respiratory failure. Many studies have analyzed the early acute phases of coronavirus disease 2019(COVID-19), but few focused on the longer-term sequelae following infection.

2 Jan 2023

New method records gene activity patterns and presence of proteins across tissues

A new method can illuminate the identities and activities of cells throughout an organ or a tumor at unprecedented resolution, according to a study co-led by researchers at Weill Cornell Medicine, NewYork-Presbyterian and the New York Genome Center.

2 Jan 2023

UKB resident awarded the C. E. Alken Prize for outstanding scientific uro-oncological research

Dr. Niklas Klümper, resident at the Clinic for Urology and working group leader at the Institute for Experimental Oncology at the University Hospital Bonn (UKB), was awarded the C. E. Alken Prize in recognition of his outstanding scientific uro-oncological work.

30 Dec 2022

Delaying antibiotic treatment does not reduce survival chances in cancer patients with neutropenic fever

In cancer patients with neutropenic fever, delaying antibiotic treatment past 60 minutes from the time of fever detection does not reduce the short-term chance of survival, according to a study in the American Journal of Medical Quality.

30 Dec 2022

Predictive models using serum miRNAs may offer objective criteria for referral to early palliative care services

A new research paper was published in Oncotarget's Volume 13 on December 17, 2022, entitled, "Serum microRNAs as new criteria for referral to early palliative care services in treatment-naïve advanced cancer patients."

29 Dec 2022

Tumor News and Research

Study details the “immunometabolic editing” mechanism of tumor evolution

Free spike proteins in the blood appear to play a role in myocarditis post-COVID mRNA vaccine

Immune system B-cells may be better in predicting HER2-positive breast cancer treatment response

Mediterranean diet may benefit health in part by incorporating moderate wine consumption

Study shows the potential of a game-changing drug to treat upper urinary tract urothelial cancers

New dual-action, cancer-killing vaccine tested in an advanced mouse model of glioblastoma

Distinct genomic patterns of malignant peripheral nerve sheath tumors may help with early diagnosis

The relationship between metabolic disease and alternations in lipid homeostasis

Precise 3D imaging can help measure radiation during cancer treatment

Technical advances expand the application of mass spectrometry imaging in pharmaceutical research

Novel triple immunotherapy combination improves anti-tumor responses in preclinical models of pancreatic cancer

The role of exosomes in osteosarcoma diagnosis, prognosis, and therapeutics

Researchers identify novel gene mechanism in most aggressive kidney cancers

Bacterial outer membrane vesicles: utility as vaccines and novel engineering approaches

Weighing risks of a major surgery: 7 questions older Americans should ask their surgeon

Why do some people develop persistent lung sequelae after severe COVID-19?

New method records gene activity patterns and presence of proteins across tissues

UKB resident awarded the C. E. Alken Prize for outstanding scientific uro-oncological research

Delaying antibiotic treatment does not reduce survival chances in cancer patients with neutropenic fever

Predictive models using serum miRNAs may offer objective criteria for referral to early palliative care services

Industry Focus eBook - Cell & Gene Therapy (1st Edition) eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Latest News