Pathology News and Research

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Pathology is the study and diagnosis of disease through examination of organs, tissues, bodily fluids, and whole bodies (autopsies). The term also encompasses the related scientific study of disease processes, called General pathology. Medical pathology is divided in two main branches, Anatomical pathology and Clinical pathology. Veterinary pathology is concerned with animal disease whereas Phytopathology is the study of plant diseases.

AI pathology diagnostic tool developed using deep learning technology from Olympus

Since 2017, Olympus Corporation has participated in a joint research program that has the potential to help streamline the workload of clinical pathologists, called “A New Approach to Develop Computer-Aided Diagnosis Using Artificial Intelligence (AI) for Gastric Biopsy Specimens”.

From Evident Corporation - Life Sciences 18 Oct 2018

Chronic sleep disruption in early adult life accelerates AD-related tau pathology

Lack of sleep during adolescence and early adulthood accelerates Alzheimer’s disease-related tau pathology, finds a study of male and female mice published in JNeurosci.

17 Oct 2018

Researchers to develop new stem cell-based strategies for treating vision disorders

A team from the University of Pennsylvania, Children's Hospital of Philadelphia, and University of Wisconsin--Madison are launching a project to develop new strategies for treating vision disorders using cells implanted in the retina.

17 Oct 2018

Down syndrome may hold important clues to onset of Alzheimer's disease

At first glance, Down syndrome and Alzheimer's disease, two severe brain abnormalities, may seem to have little in common. Down syndrome is a hereditary disease, the source of which has long been recognized--a triplication of chromosome 21.

17 Oct 2018

Expanding the knowledge about hippocampus to better understand cognitive deficits in MS

A recent article by a team of international experts on multiple sclerosis (MS) underscores the importance of expanding the knowledge base about the hippocampus in order to better understand the genesis of cognitive deficits and develop new treatment strategies.

17 Oct 2018

Age-related estrogen increase may be the culprit behind inguinal hernias in men

An age-related increase in estrogen may be the culprit behind inguinal hernias, a condition common among elderly men that often requires corrective surgery, according to a Northwestern Medicine study was published Oct. 15 in Proceedings of the National Academy of Sciences.

16 Oct 2018

Zebrafish study uncovers molecular 'brake' that helps control eye lens development

How different cells in a multicellular organism acquire their identities remains a fundamental mystery of development. In the eye, for example, the lens contains two cell types - lens epithelial cells and lens fiber cells -- the first of which differentiates into the second as an animal matures.

16 Oct 2018

Neuropsychiatric symptoms related to earliest stages of Alzheimer's brain pathology

UC San Francisco researchers, in collaboration with the unique Brazilian Biobank for Aging Studies at the University of São Paulo, have shown that the earliest stages of the brain degeneration associated with Alzheimer's disease are linked to neuropsychiatric symptoms including anxiety, depression, loss of appetite, and sleep disturbances.

15 Oct 2018

Findings offer new insight into early changes that occur during AD pathology

Alzheimer's disease (AD) is the most common form of dementia, involving memory loss and a reduction in cognitive abilities.

12 Oct 2018

New transgenic mouse model sheds light on biological causes of Parkinson's disease

Parkinson's disease is a neurodegenerative disorder that presents clinically with abnormal movement and tremors at rest.

12 Oct 2018

Many breast cancer patients share and discuss their experiences on Twitter, study finds

Twitter is a place where many cancer patients go to share and discuss their experiences of the disease. This is the main finding of a recent exploratory study (1), to be presented at the ESMO 2018 Congress in Munich, which analyzed the contents of over 6,000 tweets and retweets about breast cancer.

12 Oct 2018

Lab grown retinal cells provide clues to color blindness treatment

Researchers have grown human retinal cells in the laboratories and thus attempted to understand the basis of color vision and its development in humans. The results showed that certain hormones are essential for the development of color vision in humans and were published in the latest issue of the journal Science.

11 Oct 2018

How Does Amyloid Formation Impact Neurodegenerative Disease?

An interview with Dr Rosie Staniforth discussing her research into amyloid formation and its impact on neurodegenerative diseases.

From Postnova Analytics 11 Oct 2018

Columbia scientist and collaborators receive $11.3 million to find new targets against brain disease

Anthony Fitzpatrick, PhD, a Principal Investigator at Columbia's Zuckerman Institute and Columbia University Irving Medical Center, together with scientists from the Mayo Clinic and Boston Children's Hospital, has been awarded $11.3 million to map the three-dimensional structures of protein tangles that accumulate in the human brain.

11 Oct 2018

Study sheds light on lupus's autoimmune origins in precursor cells

In the autoimmune disease systemic lupus erythematosus or SLE, the immune system produces antibodies against parts of the body itself. How cells that produce those antibodies escape the normal "checks and balances" has been unclear, but recent research from Emory University School of Medicine sheds light on a missing link.

11 Oct 2018

Molecular mechanisms behind therapeutic action of ancient herbal medicine discovered

Researchers in the Department of Physiology & Biophysics at the University of California, Irvine School of Medicine have discovered the molecular basis for a therapeutic action of an ancient herbal medicine used across Africa to treat various illnesses, including epilepsy.

10 Oct 2018

Drug treatment at a young age could help reverse autism-like behavior in tuberous sclerosis

New research on autism has found, in a mouse model, that drug treatment at a young age can reverse social impairments. But the same intervention was not effective at an older age.

10 Oct 2018

CDx Diagnostics announces WATS3D data demonstrating crypt dysplasia as risk factor for esophageal cancer

CDx Diagnostics, an innovator in computer synthesized, three dimensional tissue analysis for the early detection and surveillance of Barrett’s esophagus, today announced new data for WATS3D, or Wide Area Transepithelial Sampling with 3D Tissue Analysis, demonstrating the clinical significance of crypt dysplasia as an important risk factor for progression to high-grade esophageal dysplasia or esophageal cancer.

9 Oct 2018

Prenatal inflammation may explain why some infants are more prone to neonatal sepsis

Each year 15 million infants are born preterm and face high risks of short- and long-term complications, including sepsis, severe inflammation of the gut, and neurodevelopmental disorders.

9 Oct 2018

Massively parallel single-nucleus RNA sequencing reveals insights into heart disease

Scientists using a powerful new technology that sequences RNA in 20,000 individual cell nuclei have uncovered new insights into biological events in heart disease.

9 Oct 2018

Pathology News and Research

Further Reading

AI pathology diagnostic tool developed using deep learning technology from Olympus

Chronic sleep disruption in early adult life accelerates AD-related tau pathology

Researchers to develop new stem cell-based strategies for treating vision disorders

Down syndrome may hold important clues to onset of Alzheimer's disease

Expanding the knowledge about hippocampus to better understand cognitive deficits in MS

Age-related estrogen increase may be the culprit behind inguinal hernias in men

Zebrafish study uncovers molecular 'brake' that helps control eye lens development

Neuropsychiatric symptoms related to earliest stages of Alzheimer's brain pathology

Findings offer new insight into early changes that occur during AD pathology

New transgenic mouse model sheds light on biological causes of Parkinson's disease

Many breast cancer patients share and discuss their experiences on Twitter, study finds

Lab grown retinal cells provide clues to color blindness treatment

How Does Amyloid Formation Impact Neurodegenerative Disease?

Columbia scientist and collaborators receive $11.3 million to find new targets against brain disease

Study sheds light on lupus's autoimmune origins in precursor cells

Molecular mechanisms behind therapeutic action of ancient herbal medicine discovered

Drug treatment at a young age could help reverse autism-like behavior in tuberous sclerosis

CDx Diagnostics announces WATS3D data demonstrating crypt dysplasia as risk factor for esophageal cancer

Prenatal inflammation may explain why some infants are more prone to neonatal sepsis

Massively parallel single-nucleus RNA sequencing reveals insights into heart disease

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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