Immune System News and Research

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Genetic bottlenecks could impact Wyoming toads' ability to respond to new pathogens

A new study from North Carolina State University examines immune system diversity in the critically endangered Wyoming toad and finds that genetic bottlenecks could impact a species' ability to respond to new pathogens.

28 Apr 2022

Yale researchers identify immune system culprit in severe COVID cases

Yale researchers have identified a particular immune response pathway that leads to severe illness and death in people infected by the SARS-CoV-2 virus.

28 Apr 2022

Novel method could bring life-saving benefits of CAR T-cell therapy to patients with acute myeloid leukemia

Massachusetts General Hospital researchers have developed a novel treatment strategy that has the potential to bring the life-saving benefits of chimeric antigen receptor T-cell therapy (CAR T) to patients with acute myeloid leukemia (AML) the most common form of leukemia in adults.

28 Apr 2022

Black and Hispanic people get the same benefits from CAR-T therapy as white patients

CAR-T therapy, a form of immunotherapy that revs up T-cells to recognize and destroy cancer cells, has revolutionized the treatment of blood cancers, including certain leukemias, lymphomas, and most recently, multiple myeloma.

28 Apr 2022

Review aims to deepen the understanding of the role of natural killer cells in COVID-19

In a recent study published in Biomedicines, researchers explored the utility of natural killer (NK) cells in coronavirus disease 2019 (COVID-19).

28 Apr 2022

The added value of adequate immune fitness to the existing approaches to pandemic preparedness

Researchers described two studies, the CLOFIT retrospective study and the COTEST real-time study, that investigated if maintaining adequate immune fitness could significantly add to the current strategies of preparedness for COVID-19 and other pandemics.

28 Apr 2022

MAPK pathway mutations can provide “precision” treatment targets for head and neck cancer

About one-fifth of often deadly head and neck cancers harbor genetic mutations in a pathway that is key to normal cell growth, and scientists report those mutations, which enable abnormal cancer cell growth, can also make the cancer vulnerable.

28 Apr 2022

Study illuminates why cowpea mosaic virus is exceptionally effective against cancer

A plant virus that infects legumes, called cowpea mosaic virus, has a special power that you may not have known about: when injected into a tumor, it triggers the immune system to treat the cancer - even metastatic cancer - and prevents it from recurring.

27 Apr 2022

New insight into the body’s response to tuberculosis may help design a more effective vaccine

More than 1.7 billion people - or a quarter of the world's population - are infected with Mycobacterium tuberculosis, the bacterial strain that causes tuberculosis (TB).

27 Apr 2022

Researchers identify four new target molecules for future personalized MS treatment

Currently available therapies to treat multiple sclerosis (MS) lack precision and can lead to serious side effects.

27 Apr 2022

Penn scientists discover how one inflammatory disorder increases susceptibility to another

The immune system remembers. Often this memory, primed by past encounters with threats like bacteria or viruses, is an asset. But when that memory is sparked by internal drivers, like chronic inflammation, it can prove detrimental, perpetuating a misguided immune response.

27 Apr 2022

Research shows existence of a link between atherosclerotic plaques and the central nervous system

A new research shows the existence of a connection between atherosclerotic plaques and the central nervous system.

27 Apr 2022

Genetic cause of lupus identified

An international team of researchers has identified DNA mutations in a gene that senses viral RNA, as a cause of the autoimmune disease lupus, with the finding paving the way for the development of new treatments.

27 Apr 2022

Gene discovery could pave the way for new and more effective treatments for lupus

Researchers from The Australian National University have identified a gene called TLR7 that, when over-activated, is responsible for causing lupus, an autoimmune disease that can be life-threatening in severe cases.

27 Apr 2022

Blood test could aid in the differential diagnosis of preeclampsia and COVID-19 in pregnant women

Pregnancy brings deep changes in women's physiology, especially regarding her blood system. The placenta is the organ which ensures an efficient communication between the mother and the baby.

27 Apr 2022

Administration of a lipid reduces inflammation associated with multiple sclerosis in mice

A team led by the Institut de Neurociències at the Universitat Autònoma de Barcelona managed to reduce chronic inflammation associated with multiple sclerosis in mice thanks to the administration of a type of lipid that mediates inflammation.

27 Apr 2022

Moderate fitness levels produce significantly larger immune response in breast cancer survivors

A new study in breast cancer survivors has found that chemotherapy, while a critical part of breast cancer therapy, may also have some lasting dampening effects on natural immunity, but moderate fitness improvements can offer some protection against this effect.

26 Apr 2022

Unhealthy air increases the chances of catching COVID-19

A Swedish study published in the journal JAMA Network Open investigates the association between short-term exposure to air pollution and SARS-CoV-2 infection.

26 Apr 2022

Common subcutaneous antibody therapy for immunodeficient patients has anti-SARS-CoV-2 antibodies

Researchers at the University of Texas Medical Branch recently confirmed the presence of neutralizing antibodies to SARS--COV-2 in a common subcutaneous antibody therapy (Hizentra) used to treat immunocompromised or immunodeficient patients, citing its protective benefits to the immunocompromised patient community.

25 Apr 2022

Reprogrammed macrophages promote the settlement of breast cancer metastases in the lungs

Metastatic breast cancer cells abuse macrophages, a type of immune cell, to promote the settlement of cancer metastases in the lungs.

25 Apr 2022

Immune System News and Research

Genetic bottlenecks could impact Wyoming toads' ability to respond to new pathogens

Yale researchers identify immune system culprit in severe COVID cases

Novel method could bring life-saving benefits of CAR T-cell therapy to patients with acute myeloid leukemia

Black and Hispanic people get the same benefits from CAR-T therapy as white patients

Review aims to deepen the understanding of the role of natural killer cells in COVID-19

The added value of adequate immune fitness to the existing approaches to pandemic preparedness

MAPK pathway mutations can provide “precision” treatment targets for head and neck cancer

Study illuminates why cowpea mosaic virus is exceptionally effective against cancer

New insight into the body’s response to tuberculosis may help design a more effective vaccine

Researchers identify four new target molecules for future personalized MS treatment

Penn scientists discover how one inflammatory disorder increases susceptibility to another

Research shows existence of a link between atherosclerotic plaques and the central nervous system

Genetic cause of lupus identified

Gene discovery could pave the way for new and more effective treatments for lupus

Blood test could aid in the differential diagnosis of preeclampsia and COVID-19 in pregnant women

Administration of a lipid reduces inflammation associated with multiple sclerosis in mice

Moderate fitness levels produce significantly larger immune response in breast cancer survivors

Unhealthy air increases the chances of catching COVID-19

Common subcutaneous antibody therapy for immunodeficient patients has anti-SARS-CoV-2 antibodies

Reprogrammed macrophages promote the settlement of breast cancer metastases in the lungs

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