Immune System News and Research

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Inhaled recombinant IL-15 tested in pet dogs with metastatic lung disease from osteosarcoma or melanoma

A protein that the body naturally produces could become an important new immunotherapy drug in the cache of cancer-fighting tools available to oncologists.

9 Jun 2022

Researchers reveal important factor behind cancer therapy resistance and a way to counter it

Why doesn't every cancer patient respond to immunotherapy? That's the question that researcher Daniel Peeper is looking to answer.

9 Jun 2022

Researchers demonstrate the double advantage of killer T-cells used in cancer immunotherapy

To grow, tumors rely on a specific structure, the tumor stroma. This includes blood vessels, which provide the nutrients necessary for the multiplication of diseased cells, and of lymphatic vessels, through which they migrate to metastasize.

9 Jun 2022

New understanding about malaria immunity could lead to the development of effective vaccines

Understanding how people exposed to malaria for the first time develop immunity could lead to creating more effective treatments including vaccines to fight the disease, researchers say.

9 Jun 2022

People with inflammatory immune conditions had increased risk of COVID-19-related death before vaccination

People with certain inflammatory immune conditions affecting the joints, bowel and skin, such as rheumatoid arthritis, may have been more at risk of dying or needing hospital care if they got COVID-19 before vaccination compared with the general population, according to a new study published in The Lancet Rheumatology.

9 Jun 2022

Synthetic IL-9 receptor allows T cells to fight cancer without the need for chemo or radiation

Before a patient can undergo T cell therapy designed to target cancerous tumors, the patient's entire immune system must be destroyed with chemotherapy or radiation. The toxic side effects are well known, including nausea, extreme fatigue and hair loss.

8 Jun 2022

Research suggests two protein coding genes can predict severe COVID-19

In a recent study posted to the medRxiv* pre-print server, researchers demonstrated that two genes, GTPase, IMAP Family Member 7 (GIMAP7), and sphingosine-1-phosphate receptor 2 (S1PR2), have the potential to predict severe coronavirus disease 2019 (COVID-19) with ~90% accuracy.

8 Jun 2022

SARS-CoV-2 ORF8 protein binds to dendritic cells and induces a hyper-inflammatory cytokine storm

In a recent study posted to the bioRxiv* pre-print server, researchers examined how the interaction of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) open reading frame 8 (ORF8) protein with host dendritic cells (DCs) induced cytokine storm.

8 Jun 2022

New therapeutic avoids major allergic reactions while maintaining therapeutic activity

Several years ago, a promising therapeutic using stem cell factor (SCF) emerged that could potentially treat a variety of ailments, such as ischemia, heart attack, stroke and radiation exposure.

8 Jun 2022

The origin of monkeypox outbreaks in non-endemic nations

In a recent review, the author explained the causes of the mysterious origin of the recent monkeypox outbreaks in non-endemic nations outside Africa.

8 Jun 2022

Open multiplexing with Cell DIVE offers cancer researchers more choices

Leica has introduced a new generation of its multiplexed imaging solution, Cell DIVE, including software and hardware improvements. The more scalable and efficient multiplexing platform addresses spatial cell biology and function within the tissue microenvironment

From Leica Microsystems GmbH 8 Jun 2022

Targeted dietary measures can reduce the symptom burden in allergic reactions, trial shows

Micronutrient deficiencies can promote inflammation and render the immune system particularly sensitive to allergenic substances.

8 Jun 2022

Gastrointestinal complications caused by SARS-CoV-2

scientists discuss the gastrointestinal complications associated with COVID-19.

7 Jun 2022

Oral administration of rapamycin increases β-amyloid buildup in Alzheimer's disease mouse model

Researchers from The University of Texas Health Science Center at San Antonio (UT Health San Antonio) have found that oral administration of rapamycin to an Alzheimer's disease mouse model causes an increase in beta (β)-amyloid protein plaques. β-amyloid buildup is a hallmark of Alzheimer's disease.

7 Jun 2022

Study reveals how common drug-resistant superbug responds to ‘last resort’ antibiotic

A study published today in Cell Reports reveals how populations of a bacterium called Pseudomonas respond to being treated with Colistin, a 'last resort' antibiotic for patients who have developed multi-drug resistant infections.

7 Jun 2022

Com-COV 3 study focuses on assessing a third dose booster vaccination for young people aged 12 to 15

The Com-COV 3 study has been commissioned through the NIHR and backed by £2.8 million government funding, with support from both the Vaccine Taskforce and National Institute for Health and Care Research (NIHR).

7 Jun 2022

Study offers insights into genetic factors that affect immunological responses in type 1 diabetes

New insights into how genetic factors affect the body's immune response in type 1 diabetes have been published in eLife.

7 Jun 2022

New microbubble-assisted ultrasound-guided immunotherapy helps improve anti-tumor immunity

Researchers at UT Southwestern have developed a first-of-its-kind ultrasound-guided cancer immunotherapy platform that delivers immune-stimulating agents to cells for the development of systemic anti-tumor immunity.

7 Jun 2022

Autoantibody found to cause schizophrenia-like behaviors in mice

Schizophrenia is a disorder that affects how people act, think, and perceive reality. It is often very difficult to treat because it has many different causes and symptoms.

6 Jun 2022

Chemo-immunotherapy combination shows promise against pancreatic cancer

A combination of chemotherapy with an immunotherapy meant to unleash the anticancer capacity of the immune system was effective against one of the hardest targets in cancer care, pancreatic cancer, in a national, randomized clinical trial led by researchers at the Perelman School of Medicine at the University of Pennsylvania, and sponsored by the Parker Institute for Cancer Immunotherapy.

6 Jun 2022

Immune System News and Research

Inhaled recombinant IL-15 tested in pet dogs with metastatic lung disease from osteosarcoma or melanoma

Researchers reveal important factor behind cancer therapy resistance and a way to counter it

Researchers demonstrate the double advantage of killer T-cells used in cancer immunotherapy

New understanding about malaria immunity could lead to the development of effective vaccines

People with inflammatory immune conditions had increased risk of COVID-19-related death before vaccination

Synthetic IL-9 receptor allows T cells to fight cancer without the need for chemo or radiation

Research suggests two protein coding genes can predict severe COVID-19

SARS-CoV-2 ORF8 protein binds to dendritic cells and induces a hyper-inflammatory cytokine storm

New therapeutic avoids major allergic reactions while maintaining therapeutic activity

The origin of monkeypox outbreaks in non-endemic nations

Open multiplexing with Cell DIVE offers cancer researchers more choices

Targeted dietary measures can reduce the symptom burden in allergic reactions, trial shows

Gastrointestinal complications caused by SARS-CoV-2

Oral administration of rapamycin increases β-amyloid buildup in Alzheimer's disease mouse model

Study reveals how common drug-resistant superbug responds to ‘last resort’ antibiotic

Com-COV 3 study focuses on assessing a third dose booster vaccination for young people aged 12 to 15

Study offers insights into genetic factors that affect immunological responses in type 1 diabetes

New microbubble-assisted ultrasound-guided immunotherapy helps improve anti-tumor immunity

Autoantibody found to cause schizophrenia-like behaviors in mice

Chemo-immunotherapy combination shows promise against pancreatic cancer

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