Pathology News and Research

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Pathology is the study and diagnosis of disease through examination of organs, tissues, bodily fluids, and whole bodies (autopsies). The term also encompasses the related scientific study of disease processes, called General pathology. Medical pathology is divided in two main branches, Anatomical pathology and Clinical pathology. Veterinary pathology is concerned with animal disease whereas Phytopathology is the study of plant diseases.

Physical activity may have beneficial effects for people with rare Alzheimer's disease

For individuals carrying a genetic mutation that causes Alzheimer's disease, engaging in at least 2.5 hours of physical activity per week may have beneficial effects on markers of Alzheimer's disease brain changes and may delay cognitive decline, according to a new study available online by Alzheimer's & Dementia: The Journal of the Alzheimer's Association as an article in press, corrected proof.

25 Sep 2018

Toxicological evaluation and dosimetry estimation of potential PET radiotracer

The SR101 N-(3-[18F]Fluoropropyl) sulfonamide ([18F]SRF101) is a Sulforhodamine 101 derivative that was previously synthesized by our group.

25 Sep 2018

Human-oriented perspective needed to better understand Parkinson's disease

Analysis published in Drug Discovery Today reveals the gap between animal models of Parkinson's disease and our understanding of the neurodegenerative processes underlying the disease, and calls for the implementation of modern, human biology-based technologies to better understand pathological processes and improve treatment outcome.

25 Sep 2018

Harmful H. pylori may play a role in Parkinson's disease

While human genetic mutations are involved in a small number of Parkinson's disease (PD) cases, the vast majority of cases are of unknown environmental causes, prompting enormous interest in identifying environmental risk factors involved.

25 Sep 2018

Researchers highlight potential therapy for treating rare, deadly blood-clotting disorder

In proof-of-concept experiments, University of Alabama at Birmingham researchers have highlighted a potential therapy for a rare but potentially deadly blood-clotting disorder, TTP.

24 Sep 2018

Study opens new avenues for treatment of Laing distal myopathy

New avenues are now being opened for future treatment of Laing distal myopathy, a rare disorder that causes muscles in the feet, hands and elsewhere to atrophy. In a study published in the journal PNAS, researchers have identified an enzyme with a clear link to how the disease develops.

21 Sep 2018

New clinical trial evaluates aesthetic results of conservative surgery in breast cancer

Belén Merck Navarro, Medicine professor at Valencia and Castellón's CEU UCH university is the only Spaniard among the 17 surgeons from 11 different countries that specialize in breast cancer who took part in a clinical trial on the usefulness of 3D images to evaluate the aesthetic results of conservative surgery in breast cancer

21 Sep 2018

TINY cancer detection device shows promise as point-of-care detector of KSHV

Its name is an acronym used to convey its size, but researchers at Cornell Engineering and Weill Cornell Medicine are hoping their hand-held cancer detection device's impact in the developing world is anything but small.

21 Sep 2018

Scientists predict how well the body will fight lung cancer by analyzing immune cell shapes

Researchers at Case Western Reserve University have discovered how to quickly and accurately predict which lung cancer patients will benefit from chemotherapy by analyzing how immune cells the body sends out to fight the disease are arranged.

20 Sep 2018

Study reveals new therapeutic target for pediatric tumor-associated intractable epilepsy

Pediatric brain tumors are characterized by frequent complications due to intractable epilepsy compared to adult brain tumors. However, the genetic cause of refractory epilepsy in pediatric brain tumors has not been elucidated yet, and it is difficult to treat patients because the tumors do not respond to existing antiepileptic drugs and debilitate children's development.

19 Sep 2018

Experts to present research on prevention, management of dysphagia at international conference

Over 800 delegates from 46 countries will attend the 8th annual European Society for Swallowing Disorders Congress taking place in Dublin next week to hear about new developments in swallowing disorder research.

19 Sep 2018

Investigators determine specific treatable traits that can predict future asthma attacks

Investigators have assessed the prevalence of treatable traits in severe asthma and have determined which specific traits are predictive of future asthma attacks.

19 Sep 2018

Penn researchers find common thread linking almost all TNR expansion diseases

In a class of roughly 30 neurological disorders that includes ALS, Huntington's Disease and Fragile X Syndrome, the relevant mutant gene features sections of repeating base pair sequences known as short tandem repeats, or STRs. Healthy people have STRs of normal lengths distributed across their DNA.

19 Sep 2018

KAIST researchers develop heart-targeting drug delivery technology using tannin acid

Typical methods of drug delivery to the heart require surgical procedures involving incisions in the chest wall and bones.

18 Sep 2018

Researchers identify key step in how plant cells respond to pathogens

Just like humans, plants have an immune system that helps them fight off infections. Plant immunity has some important differences: they don't make antibodies and can't fight off the same bug more quickly months or years later.

18 Sep 2018

Lymphatic vessels surrounding the brain play crucial role in multiple sclerosis, research suggests

Lymphatic vessels that clean the brain of harmful material play a crucial role in the development and progression of multiple sclerosis, new research from the University of Virginia School of Medicine suggests.

18 Sep 2018

Machine learning program could distinguish between two lung cancer types

A new computer program can analyze images of patients' lung tumors, specify cancer types, and even identify altered genes driving abnormal cell growth, a new study shows.

17 Sep 2018

Case Western Reserve professor wins $2 million grant to study colorectal cancer

Lan Zhou, MD, PhD, associate professor of pathology at Case Western Reserve University School of Medicine, has received a five-year, $2 million grant from the National Cancer Institute of the National Institutes of Health to study human colorectal cancer.

14 Sep 2018

Study: aPKC inhibitors may provide new therapeutic option for blinding eye diseases

Many eye diseases, including diabetic retinopathy and macular degeneration, exhibit increased permeability of blood vessels in the macular (central) portion of the retina leading to abnormal fluid accumulation and vision loss.

14 Sep 2018

US Department of Defense offers three-year grant for UIC study on prostate cancer

A new three-year grant totaling nearly $1 million from the U.S. Department of Defense will fund University of Illinois at Chicago research on the gene SELENOF and its role in the development of prostate cancer among black men.

14 Sep 2018

Pathology News and Research

Further Reading

Physical activity may have beneficial effects for people with rare Alzheimer's disease

Toxicological evaluation and dosimetry estimation of potential PET radiotracer

Human-oriented perspective needed to better understand Parkinson's disease

Harmful H. pylori may play a role in Parkinson's disease

Researchers highlight potential therapy for treating rare, deadly blood-clotting disorder

Study opens new avenues for treatment of Laing distal myopathy

New clinical trial evaluates aesthetic results of conservative surgery in breast cancer

TINY cancer detection device shows promise as point-of-care detector of KSHV

Scientists predict how well the body will fight lung cancer by analyzing immune cell shapes

Study reveals new therapeutic target for pediatric tumor-associated intractable epilepsy

Experts to present research on prevention, management of dysphagia at international conference

Investigators determine specific treatable traits that can predict future asthma attacks

Penn researchers find common thread linking almost all TNR expansion diseases

KAIST researchers develop heart-targeting drug delivery technology using tannin acid

Researchers identify key step in how plant cells respond to pathogens

Lymphatic vessels surrounding the brain play crucial role in multiple sclerosis, research suggests

Machine learning program could distinguish between two lung cancer types

Case Western Reserve professor wins $2 million grant to study colorectal cancer

Study: aPKC inhibitors may provide new therapeutic option for blinding eye diseases

US Department of Defense offers three-year grant for UIC study on prostate cancer

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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