Pathology News and Research

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Pathology is the study and diagnosis of disease through examination of organs, tissues, bodily fluids, and whole bodies (autopsies). The term also encompasses the related scientific study of disease processes, called General pathology. Medical pathology is divided in two main branches, Anatomical pathology and Clinical pathology. Veterinary pathology is concerned with animal disease whereas Phytopathology is the study of plant diseases.

Jaw joint bone appears to evolve based on animal's size rather than its diet

Chewing: We don't think about it, we just do it. But biologists don't know a lot about how chewing behavior leaves telltale signs on the underlying bones.

31 Aug 2018

Neurons play active role in triggering a defense mechanism that leads to their own damage

Rasmussen's encephalitis is a rare autoimmune disease that primarily affects children and can lead to seizures.

31 Aug 2018

Subcutaneous injection of new protein helps treat hemophilia more effectively

Patients with hemophilia bleed spontaneously or following trauma. The most common sites of bleeding are into joints, but bleeds can also happen into any tissue in the body including the muscles, brain, or eyes.

31 Aug 2018

Researchers provide new virulence clues through genomic study of anthrax strains

By analyzing genomic sequences from more than 400 strains of the bacterium that causes anthrax, researchers have provided the first evidence that the severity - technically known as virulence - of specific strains may be related to the number of copies of certain plasmids they carry.

30 Aug 2018

Study yields therapeutic clues to combat drug resistance in rare aggressive cancer

Stephen Elledge, PhD, and his team did not set out to find therapies that could render tumors less resistant to therapy or make existing drugs more potent against a rare form of cancer. But these are precisely the clinical insights that their most recent study has yielded.

29 Aug 2018

Researchers find how NF2 gene mutations lead to out-of-control cellular proliferation

A team of Massachusetts General Hospital Cancer Center researchers has determined one way that mutations in a gene involved in a rare, hereditary cancer syndrome lead to out-of-control cellular proliferation.

29 Aug 2018

New lung tissue-on-a-chip system offers rapid testing of potential anti-fibrotic treatments

Pulmonary fibrosis is one of the most common and serious types of lung disease. Now NIBIB-funded researchers have developed an in vitro lung tissue-on-a-chip system that mimics lung fibrosis, offering rapid testing of potential new anti-fibrotic treatments.

28 Aug 2018

A non-canonical approach may improve radiation treatment for cancer

Although the success or failure of radiation therapy for cancer has long been associated with the intrinsic radio-resistance or radio-sensitivity of tumor cells, a new approach is demonstrating that radiation can take credit for an additional benefit - causing highly effective secondary immune responses that can enhance anti-tumor immunity.

28 Aug 2018

New findings reveal potential role of interleukin-1 alpha in risk for heart attacks, strokes

XBiotech Inc. announced today the publication of findings that point toward a white blood cell-derived interleukin-1 alpha (IL-1⍺) as a cause of blood clots that could lead to heart attacks or strokes.

28 Aug 2018

NorthShore University HealthSystem highlights utility of Streck ARM-D Kits for antimicrobial resistance detection

Streck, Inc., received great interest for Streck ARM-D Kits, used in the detection of antibiotic resistance, at ASM Microbe 2018 in Atlanta.

28 Aug 2018

New personalized cellular therapy approved for use in the European Union

The European Commission has approved a personalized cellular therapy developed at the University of Pennsylvania's Abramson Cancer Center, making it the first chimeric antigen receptor (CAR) T cell therapy permitted for use in the European Union in two distinct indications.

27 Aug 2018

Sociodemographic risk adjustment can improve apparent performance of some hospitals

Sociodemographic risk adjustment of emergency care-sensitive mortality improves apparent performance of some hospitals treating a large number of nonwhite, Hispanic, or poor patients.

25 Aug 2018

Study reveals molecular mechanisms underlying expansive arterial remodeling

Expansive arterial remodeling comprises a genetically programmed biological response designed to restore homeostatic levels of arterial wall stress after an increase in vessel flow load occurs.

25 Aug 2018

Alternative method identified for delivering nusinersen to spinal muscular atrophy patients

A new report has identified an alternative method to deliver nusinersen to patients with spinal muscular atrophy using a subcutaneous intrathecal catheter system configured by connecting an intrathecal catheter to an implantable infusion port.

24 Aug 2018

New pharmacologic approach discovered to stop immune cell death

Researchers from Case Western Reserve University School of Medicine have discovered a way to stop immune cell death associated with multiple diseases, including sepsis, inflammatory bowel disease, and arthritis.

24 Aug 2018

Scientists identify molecular pit crew responsible for refueling in signaling cells

During IndyCar races, pit stop crews will often refuel a car, replace wheels and complete minor repairs on a race car within 10 seconds. In this short time, a dozen or so people work rapidly and in a highly coordinated manner to complete a number of tasks with extraordinary efficiency.

24 Aug 2018

Researchers use 'autobiographical memory' test for early prediction of Alzheimer's

Testing how well people remember past events in their lives could help medical professionals make early predictions about who is at risk for developing Alzheimer's disease, according to a new study from the University of Arizona.

24 Aug 2018

Eye exam may one day help screen patients for Alzheimer's disease

It may be possible in the future to screen patients for Alzheimer's disease using an eye exam.

23 Aug 2018

Alzheimer’s screening may one day be carried out using an eye exam

New findings suggest that it may be possible to use an eye test to screen people for their risk of developing Alzheimer’s disease.

23 Aug 2018

Scientists work towards solving mystery of incurable blood diseases

Scientists may be on the road to solving the mystery of a group of mostly incurable blood diseases called myelodysplastic syndromes, which cause people to have immature, malfunctioning bone marrow cells that fuel a diverse set of health problems and can lead to leukemia.

23 Aug 2018

Pathology News and Research

Further Reading

Jaw joint bone appears to evolve based on animal's size rather than its diet

Neurons play active role in triggering a defense mechanism that leads to their own damage

Subcutaneous injection of new protein helps treat hemophilia more effectively

Researchers provide new virulence clues through genomic study of anthrax strains

Study yields therapeutic clues to combat drug resistance in rare aggressive cancer

Researchers find how NF2 gene mutations lead to out-of-control cellular proliferation

New lung tissue-on-a-chip system offers rapid testing of potential anti-fibrotic treatments

A non-canonical approach may improve radiation treatment for cancer

New findings reveal potential role of interleukin-1 alpha in risk for heart attacks, strokes

NorthShore University HealthSystem highlights utility of Streck ARM-D Kits for antimicrobial resistance detection

New personalized cellular therapy approved for use in the European Union

Sociodemographic risk adjustment can improve apparent performance of some hospitals

Study reveals molecular mechanisms underlying expansive arterial remodeling

Alternative method identified for delivering nusinersen to spinal muscular atrophy patients

New pharmacologic approach discovered to stop immune cell death

Scientists identify molecular pit crew responsible for refueling in signaling cells

Researchers use 'autobiographical memory' test for early prediction of Alzheimer's

Eye exam may one day help screen patients for Alzheimer's disease

Alzheimer’s screening may one day be carried out using an eye exam

Scientists work towards solving mystery of incurable blood diseases

Industry Focus eBook - Cell & Gene Therapy (1st Edition) eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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