Pathology News and Research

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Pathology is the study and diagnosis of disease through examination of organs, tissues, bodily fluids, and whole bodies (autopsies). The term also encompasses the related scientific study of disease processes, called General pathology. Medical pathology is divided in two main branches, Anatomical pathology and Clinical pathology. Veterinary pathology is concerned with animal disease whereas Phytopathology is the study of plant diseases.

Immunotherapies may increase overall survival in patients with melanoma brain metastases

Among patients with cutaneous melanoma who had brain metastases (MBM), first-line treatment with a checkpoint inhibitor was associated with a 1.4-fold increase in median overall survival, according to results from a national cohort.

13 Jul 2018

New study suggests testing urine and blood serum as better way to diagnose myeloma

When it comes to diagnosing a condition in which the plasma cells that normally make antibodies to protect us instead become cancerous, it may be better to look at the urine as well as the serum of our blood for answers, pathologists say.

13 Jul 2018

Four-protein biomarker blood test improves lung cancer risk assessment for smokers

A four-protein biomarker blood test improves lung cancer risk assessment over existing guidelines that rely solely upon smoking history, capturing risk for people who have ever smoked, not only for heavy smokers, an international research team reports in JAMA Oncology.

12 Jul 2018

Novel therapeutic approach alleviates ALS-related muscular atrophy in mouse models

Supplementing a single protein found in the spinal cord could help prevent symptoms of Lou Gehrig's disease, according to a new study out of Case Western Reserve University School of Medicine.

12 Jul 2018

New biosensor could enable early non-invasive diagnosis of Alzheimer's disease through magnetic resonance imaging

UPM researchers are involved in the development of a new biosensor that can be useful to achieve an early non-invasive diagnosis of Alzheimer's disease using magnetic resonance imaging.

12 Jul 2018

Researchers elucidate role of mutations in deadly brain cancer

Researchers from the University of North Carolina Lineberger Comprehensive Cancer Center have discovered how different mutations in a specific gene help drive glioblastoma, the most lethal form of brain cancer.

11 Jul 2018

New lab-on-a-chip technology could soon help detect fetal genetic abnormalities in early pregnancy

Biomedical engineers Dr Marnie Winter and Professor Benjamin Thierry from UniSA's Future Industries Institute and the ARC Centre of Excellence in Convergent Bio-Nano Science and Technology are part of a team of researchers who have isolated fetal cells from maternal blood using a tiny microfluidic device, allowing for improved genetic testing.

11 Jul 2018

Researchers uncover molecular drivers of a deadly pediatric cancer

Researchers have made important discoveries about the molecular mechanisms driving acute myeloid leukemia (AML), a deadly pediatric cancer.

11 Jul 2018

Scientists discover ‘Big Bang’ of Alzheimer's disease

Scientists have discovered a "Big Bang" of Alzheimer's disease - the precise point at which a healthy protein becomes toxic but has not yet formed deadly tangles in the brain.

11 Jul 2018

Alternative splicing plays vital role in adult muscle mass maintenance

Despite the importance that changes in muscle mass have in aging, overall body metabolism and in chronic disease, we still don't fully understand the mechanisms that contribute to the maintenance of adult muscle mass.

11 Jul 2018

Ludwig-developed antibody drug for deadly brain cancer may have broader applications

A Ludwig Cancer Research study explains why a particular mutation in the epidermal growth factor receptor, a cell surface protein, results in more aggressive tumors and poorer overall survival of patients diagnosed with the brain cancer glioblastoma multiforme.

10 Jul 2018

Researchers focus on mechanisms involved in development of non-alcoholic fatty liver disease

One of the lines of research of the UPV/EHU's Lipids & Liver group, which focusses on the mechanisms involved in the development and progression of non-alcoholic fatty liver disease, is achieving significant advances in a range of aspects; these include the identification of proteins that alter the metabolic pathways in the development and progression of liver disease, and even cancer, and the seeking of targets to enable the disease to be reversed.

9 Jul 2018

Targeting multiple proteins may be key to treat neurodegenerative disorders

Nearly all major neurodegenerative diseases - from Alzheimer's to Parkinson's - are defined and diagnosed by the presence of one of four proteins that have gone rogue: tau, amyloid-beta, alpha-synuclein, or TDP-43.

6 Jul 2018

OGT announces direct sales and support services in Europe

Oxford Gene Technology, The Molecular Genetics Company, has announced that it is now directly selling Cytocell Fluorescence In Situ Hybridisation products through several established affiliates of SysmexCorporation in Europe following its acquisition last year.

From Oxford Gene Technology 4 Jul 2018

Mount Sinai study identifies potential new treatment target for aggressive bladder cancer

A potential new target for treatment has been identified in an aggressive form of bladder cancer, Mount Sinai researchers report.

4 Jul 2018

New computational strategy used to identify genes associated with childhood cancer

Using a new computational strategy, researchers at UT Southwestern Medical Center have identified 29 genetic changes that can contribute to rhabdomyosarcoma, an aggressive childhood cancer.

3 Jul 2018

Stem cells can re-muscularize infarcts in macaque monkey hearts, study shows

Researchers at UW Medicine in Seattle have successfully used human stem cells to restore heart function in monkeys with heart failure. The findings suggest that the technique will be effective in patients with heart failure, the leading cause of death in the world.

3 Jul 2018

Novel, stem cell-based model mimics mechanisms of Alzheimer's disease

Scientists in Dresden, Germany, have been successful in mimicking mechanisms of Alzheimer's disease in a novel, stem cell-based model system that reproduces features of human brain tissue.

3 Jul 2018

Low-dose aspirin may reduce amyloid plaques in the brain, study shows

A regimen of low-dose aspirin potentially may reduce plaques in the brain, which will reduce Alzheimer's disease pathology and protect memory, according to neurological researchers at Rush University Medical Center, who published the results of their study today in the July issue of The Journal of Neuroscience.

2 Jul 2018

Established lung fibrosis can be reversed using diabetes drug treatment

Researchers at the University of Alabama at Birmingham have shown - for the first time - that established lung fibrosis can be reversed using a drug treatment that targets cell metabolism.

2 Jul 2018

Pathology News and Research

Further Reading

Immunotherapies may increase overall survival in patients with melanoma brain metastases

New study suggests testing urine and blood serum as better way to diagnose myeloma

Four-protein biomarker blood test improves lung cancer risk assessment for smokers

Novel therapeutic approach alleviates ALS-related muscular atrophy in mouse models

New biosensor could enable early non-invasive diagnosis of Alzheimer's disease through magnetic resonance imaging

Researchers elucidate role of mutations in deadly brain cancer

New lab-on-a-chip technology could soon help detect fetal genetic abnormalities in early pregnancy

Researchers uncover molecular drivers of a deadly pediatric cancer

Scientists discover ‘Big Bang’ of Alzheimer's disease

Alternative splicing plays vital role in adult muscle mass maintenance

Ludwig-developed antibody drug for deadly brain cancer may have broader applications

Researchers focus on mechanisms involved in development of non-alcoholic fatty liver disease

Targeting multiple proteins may be key to treat neurodegenerative disorders

OGT announces direct sales and support services in Europe

Mount Sinai study identifies potential new treatment target for aggressive bladder cancer

New computational strategy used to identify genes associated with childhood cancer

Stem cells can re-muscularize infarcts in macaque monkey hearts, study shows

Novel, stem cell-based model mimics mechanisms of Alzheimer's disease

Low-dose aspirin may reduce amyloid plaques in the brain, study shows

Established lung fibrosis can be reversed using diabetes drug treatment

Industry Focus eBook - Analytical Chemistry (2nd Edition) eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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