RNA News and Research

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Ribonucleic acid (RNA) is a biologically important type of molecule that consists of a long chain of nucleotide units. Each nucleotide consists of a nitrogenous base, a ribose sugar, and a phosphate.

New study describes SARS-CoV-2 ExoN enzyme that promotes antiviral resistance

A new study describes the structure of a crucial enzyme present in SARS-CoV-2.

8 Aug 2021

New tabletop device can quickly detect SARS-CoV-2 from saliva samples

Engineers at MIT and Harvard University have designed a small tabletop device that can detect SARS-CoV-2 from a saliva sample in about an hour.

6 Aug 2021

New CRISPR-based diagnostic test detects COVID-19 variants from saliva samples

With the Delta variant wreaking havoc on unvaccinated populations and COVID-19 cases spiking around the world, the pandemic is far from over.

6 Aug 2021

Research reveals a microRNA network as putative mediators of myocardial reductive stress

Last year, University of Alabama at Birmingham researchers reported that reductive stress - an imbalance in the normal oxidation/reduction homeostasis - caused pathological changes associated with heart failure in a mouse model.

6 Aug 2021

Researchers develop a novel process for producing pure RNA

Researchers at the University of Massachusetts Amherst recently unveiled their discovery of a new process for making RNA.

6 Aug 2021

Researchers create new model for studying earliest stages of retinoblastoma

Scientists at St. JudeChildren's Research Hospital have created a laboratory model for studying retinoblastoma driven by inherited mutations in theRB1gene.Retinoblastoma is a rare cancer of the retina, the thin tissue inside the back of the eye.

6 Aug 2021

New method for producing pseudotyped virus particles bearing spike protein of SARS-CoV-2

A new study discusses the development of an improved protocol based on cell lines that can consistently express S proteins.

5 Aug 2021

Activation of NLRP3 inflammasome by the N protein of SARS-CoV-2 to induce hyperinflammation

A new study has revealed the mechanism by which the SARS-CoV-2 N protein activates NLRP3 inflammasomes to induce hyperinflammation.

5 Aug 2021

Research suggests potential new treatment strategy for phenylketonuria

Researchers at The University of Texas MD Anderson Cancer Center have discovered a critical new factor in regulating phenylalanine metabolism and, therefore, in preventing the inherited metabolic disorder phenylketonuria (PKU).

5 Aug 2021

Researchers develop the most comprehensive molecular map of lung squamous cell carcinoma

Lung cancer remains the leading cause of cancer-associated death in the United States and worldwide. Patients with a subtype called lung adenocarcinoma (LUAD) have benefited from the development of new targeted medicines, but the search for effective new therapies for another subtype called lung squamous cell carcinoma (LSCC) has largely come up short.

5 Aug 2021

Mutation in a single gene may be responsible for non-obstructive azoospermia in men

Mutation in a single gene appears to account for a form of male infertility in which men fail to produce sperm, according to an international study funded in part by the National Institutes of Health.

5 Aug 2021

Using two different CRISPR enzymes to develop a faster and easier COVID-19 diagnostic test

Frequent, rapid testing for COVID-19 is critical to controlling the spread of outbreaks, especially as new, more transmissible variants emerge.

5 Aug 2021

Could a plant metabolite in liverworts be a potent antiviral against SARS-CoV-2 and other RNA viruses?

A new study from the National Centre for Biotechnology and Medicinal Chemistry Institute suggests Mother Nature delivered — in the form of liverworts. They found that the bryophyte Marchantia polymorpha, also known as umbrella liverworts, could work as a potential antiviral treatment.

5 Aug 2021

Scientists identify new therapeutic target for several aggressive cancers

A protein in tumor cells could be targeted to treat some types of aggressive cancer including brain, blood, skin, and kidney, new research has shown.

4 Aug 2021

Heterologous prime-boost vaccination induces robust mucosal and systemic immunity against SARS-CoV-2

Scientists from Germany and Italy recently demonstrated the benefits of intramuscular/intranasal heterologous prime-boost vaccination regimen against coronavirus disease 2019 (COVID-19).

4 Aug 2021

Researchers develop nanofibrous filters that can capture and kill airborne coronaviruses under visible light irradiation

A new study discusses the development of photosensitized electrospun nanofibrous membranes capable of capturing and inactivating SARS-CoV-2 aerosols.

4 Aug 2021

Study provides new insights for understanding dynamic changes in immune responses to COVID-19

A KAIST immunology research team found that a specific subtype of macrophages that originated from blood monocytes plays a key role in the hyper-inflammatory response in SARS-CoV-2 infected lungs, by performing single-cell RNA sequencing of bronchoalveolar lavage fluid cells.

4 Aug 2021

RNA News and Research

Further Reading

New study describes SARS-CoV-2 ExoN enzyme that promotes antiviral resistance

New tabletop device can quickly detect SARS-CoV-2 from saliva samples

New CRISPR-based diagnostic test detects COVID-19 variants from saliva samples

Research reveals a microRNA network as putative mediators of myocardial reductive stress

Researchers develop a novel process for producing pure RNA

Researchers create new model for studying earliest stages of retinoblastoma

New method for producing pseudotyped virus particles bearing spike protein of SARS-CoV-2

Activation of NLRP3 inflammasome by the N protein of SARS-CoV-2 to induce hyperinflammation

Research suggests potential new treatment strategy for phenylketonuria

Researchers develop the most comprehensive molecular map of lung squamous cell carcinoma

Mutation in a single gene may be responsible for non-obstructive azoospermia in men

Using two different CRISPR enzymes to develop a faster and easier COVID-19 diagnostic test

Could a plant metabolite in liverworts be a potent antiviral against SARS-CoV-2 and other RNA viruses?

Scientists identify new therapeutic target for several aggressive cancers

Heterologous prime-boost vaccination induces robust mucosal and systemic immunity against SARS-CoV-2

Researchers develop nanofibrous filters that can capture and kill airborne coronaviruses under visible light irradiation

Study provides new insights for understanding dynamic changes in immune responses to COVID-19

Next-Generation Sequencing and the Diagnosis of Disease

Next-generation CRISPR tools and therapies improved by modified RNA guides

Inhibition of SARS-CoV-2 replication in vitro by Losartan

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