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3 million now receiving anti-retroviral therapy HIV drugs

The close of 2007 marks an important step in the history of the HIV/AIDS epidemic. Nearly 3 million people are now receiving anti-retroviral therapy (ART) in low- and middle-income countries, according to a new report jointly launched today by WHO, UNAIDS and UNICEF.

2 Jun 2008

Anti-rejection drug sirolimus may prolong organ life in noncompliant kidney transplant patients

New research from the University of California, San Diego Department of Medicine, Division of Nephrology, shows that the anti-rejection drug sirolimus (brand name Rapamune) may help prolong the clinical benefit of transplanted kidneys and delay rejection, especially in patients who do not regularly take their prescribed medications (are "non-compliant"). While the transplant field has been highly successful at reducing rejection and graft loss in the first year, post-transplant, reducing risk for graft rejection in the long-term has proved more difficult.

2 Jun 2008

Protective effects of breast milk are higher in girls than in boys

Challenging the long-standing belief that breast-feeding equally protects all babies against disease, research led by Johns Hopkins Children's Center investigators suggests that when it comes to respiratory infections, the protective effects of breast milk are higher in girls than in boys.

2 Jun 2008

UT Southwestern mouse model mimics hyperglycemia, aids in diabetes research

UT Southwestern Medical Center researchers have genetically engineered a laboratory mouse in which pancreatic beta cells can regenerate after being induced to die. The new animal model's regenerative ability may provide future insights into improved treatments of diabetes, which affects millions of Americans.

2 Jun 2008

Novel chemo drug helps treat prostate cancer

Men with a certain type of prostate cancer have been shown to respond to a new chemotherapy drug, Sagopilone, plus prednisone in an international trial led by Oregon Health & Science University Cancer Institute researchers.

1 Jun 2008

Survivors of childhood Hodgkin's lymphoma at higher risk of future health problems

Adults who survived childhood Hodgkin's Lymphoma should be especially vigilant about cancer and cardiovascular screenings, according to researchers from Wake Forest University Baptist Medical Center and colleagues.

1 Jun 2008

Expert cautions against rushing into genetic testing

Just because scientific advances now allow individuals to learn their genetic make-up doesn't mean they should rush into genetic testing in hopes of making revolutionary improvements to their health, cautions a geneticist and practicing physician at the University of North Carolina at Chapel Hill.

1 Jun 2008

Acupuncture reduces pain and dysfunction in head and neck cancer patients after neck dissection

New data from a randomized, controlled trial found that acupuncture provided significant reductions in pain, dysfunction, and dry mouth in head and neck cancer patients after neck dissection. The study was led by David Pfister, MD, Chief of the Head and Neck Medical Oncology Service, and Barrie Cassileth, PhD, Chief of the Integrative Medicine Service, at Memorial Sloan-Kettering Cancer Center (MSKCC). Dr. Pfister presented the findings today at the annual meeting of the American Society for Clinical Oncology.

1 Jun 2008

Yale researchers block transforming growth factor to clear up amyloid plaques in mice

Blocking a common immune system response cleared up plaques associated with Alzheimer's Disease and enabled treated mice to recover some lost memory, Yale University researchers report Friday in the journal Nature Medicine.

1 Jun 2008

How advanced prostate cancer becomes resistant to androgen-deprivation therapy

For the past 70 years the treatment of choice for advanced, metastatic prostate cancer has been androgen-deprivation therapy. That is, the suppression of circulating testosterone - the hormone that fuels prostate-cancer growth - via surgical castration (orchiectomy) or medical castration with testosterone-blocking drugs. While such therapy buys time for patients, it is not a cure, as inevitably the cancer becomes resistant to the androgen deprivation and continues to grow.

1 Jun 2008

Connecticut Attorney General files lawsuit against McKesson over alleged inflation of prescription drug prices

Connecticut Attorney General Richard Blumenthal (D) on Thursday filed a lawsuit in U.S. District Court in Boston over allegations that prescription drug distributor McKesson conspired to inflate the average wholesale prices of hundreds of brand-name medications in violation of federal racketeering and state consumer protection laws, the AP/Hartford Courant reports.

30 May 2008

Thailand's removal of official who supported compulsory licensing 'important' step to 'protecting patients' health,' editorial says

The Thai government's removal last week of Vichai Chokevivat -- "one of the most vocal opponents" of patent protections for drug companies -- from Governmental Pharmaceutical Organization's board is a "small" but "important" step in "restoring Thailand's international reputation and protecting patients' health," a Wall Street Journal Asia editorial says.

30 May 2008

FDA proposes drug label changes to provide more information on risks for women who are pregnant, nursing

FDA on Wednesday proposed changing its labeling system for prescription and over-the-counter drugs to provide more safety information for pregnant and breastfeeding women, the AP/Long Island Newsday reports (AP/Long Island Newsday, 5/28). On average, women in the U.S. take three to five medications when they are pregnant, and more than 90% of women who are breastfeeding take medications during the first week after delivery, USA Today reports.

30 May 2008

Grassley inquiry into fast-tracking of Avastin drug applications could hurt cancer drug development, patients

Sen. Chuck Grassley's (R-Iowa) request that the Government Accountability Office investigate whether FDA acted appropriately in granting "accelerated approval" to a cancer drug "will have a catastrophic effect on America's ability to develop new drugs," Mark Thornton, a former medical officer in FDA's Office of Oncology Drug Products and president of the Sarcoma Foundation of America, writes in a Wall Street Journal opinion piece.

30 May 2008

Self-assembled viruses

Viruses are true experts at importing genetic material into the cells of an infected organism. This trait is now being exploited for gene therapy, in which genes are brought into the cells of a patient to treat genetic diseases or genetic defects. Korean researchers have now made an artificial virus. As described in the journal Angewandte Chemie, they have been able to use it to transport both genes and drugs into the interior of cancer cells.

30 May 2008

Novel replacement for conventional needle and syringe

Chris Holden (21), A third year design student at Northumbria University, has won a prestigious national award for medical design by redesigning the conventional needle and syringe.

30 May 2008

Body's baking soda used to catch cancer early

A chemical commonly called baking soda which is found naturally in the body could be used to detect cancer with magnetic resonance imaging, reveals a Cancer Research UK study published in Nature.

29 May 2008

Fireflies' glow helps researchers track cancer drug's effectiveness

The gene that allows fireflies to flash is helping researchers track the effectiveness of anti-cancer drugs over time.

29 May 2008

Brand-name prescription drug companies reached 14 deals with generic manufacturers to delay sale of generics in FY 2007

Brand-name prescription drug makers in fiscal year 2007 reached 14 agreements with generic drug makers to delay market entry of generic medications, according to a report released on Wednesday by the Federal Trade Commission, Reuters reports (Bartz, Reuters, 5/23).

28 May 2008

U.S. Government 'must take lead' in health care IT, former Rep. Johnson writes

There are online tools that "can remember what books you ordered over the last three years," so "why can't your doctor's computer remind him" of the details related to patients' prescription drugs, insurance or other procedures, former Rep. Nancy Johnson (R-Conn.), a senior public policy adviser for Baker Donelson, writes in a Washington Times opinion piece.

28 May 2008

Drugs News and Research

3 million now receiving anti-retroviral therapy HIV drugs

Anti-rejection drug sirolimus may prolong organ life in noncompliant kidney transplant patients

Protective effects of breast milk are higher in girls than in boys

UT Southwestern mouse model mimics hyperglycemia, aids in diabetes research

Novel chemo drug helps treat prostate cancer

Survivors of childhood Hodgkin's lymphoma at higher risk of future health problems

Expert cautions against rushing into genetic testing

Acupuncture reduces pain and dysfunction in head and neck cancer patients after neck dissection

Yale researchers block transforming growth factor to clear up amyloid plaques in mice

How advanced prostate cancer becomes resistant to androgen-deprivation therapy

Connecticut Attorney General files lawsuit against McKesson over alleged inflation of prescription drug prices

Thailand's removal of official who supported compulsory licensing 'important' step to 'protecting patients' health,' editorial says

FDA proposes drug label changes to provide more information on risks for women who are pregnant, nursing

Grassley inquiry into fast-tracking of Avastin drug applications could hurt cancer drug development, patients

Self-assembled viruses

Novel replacement for conventional needle and syringe

Body's baking soda used to catch cancer early

Fireflies' glow helps researchers track cancer drug's effectiveness

Brand-name prescription drug companies reached 14 deals with generic manufacturers to delay sale of generics in FY 2007

U.S. Government 'must take lead' in health care IT, former Rep. Johnson writes

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