Pathology News and Research

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Pathology is the study and diagnosis of disease through examination of organs, tissues, bodily fluids, and whole bodies (autopsies). The term also encompasses the related scientific study of disease processes, called General pathology. Medical pathology is divided in two main branches, Anatomical pathology and Clinical pathology. Veterinary pathology is concerned with animal disease whereas Phytopathology is the study of plant diseases.

World’s most common curable STI disproportionately affects black community, study finds

In a new Johns Hopkins study, researchers have added to evidence that Trichomonas vaginalis (TV), the world's most common curable sexually transmitted infection (STI), disproportionately affects the black community.

15 Mar 2018

Study highlights divergent molecular mechanisms contributing to depression in men and women

Men and women with major depressive disorder have opposite changes in the expression of the same genes, according to a new postmortem brain study by researchers at the University of Pittsburgh and Centre for Addiction and Mental Health, Toronto, Canada.

14 Mar 2018

Precision oncology may improve overall survival, lower healthcare costs for advanced cancer patients

The use of advanced molecular diagnostic technologies, such as Next-Generation Sequencing-based gene panel testing, to select targeted therapies in advanced cancer patients is known as precision oncology.

13 Mar 2018

Study highlights potential of ASO therapy to treat Fuchs endothelial corneal dystrophy patients

A proof-of-concept study carried out at UCL Institute of Ophthalmology with funding from Fight for Sight has highlighted the potential of a targeted antisense oligonucleotide therapy to treat Fuchs endothelial corneal dystrophy patients with a mutation in the TCF4 gene.

12 Mar 2018

TSRI researchers show path to developing treatments for Charcot-Marie-Tooth disease

Scientists at The Scripps Research Institute have now shown a path to developing treatments for disease subtype CMT2D.

8 Mar 2018

New study examines origin of cryptococcosis within the central nervous system

A particular fungal infection is responsible for more than 220,000 cases of cryptococcosis worldwide each year in people with HIV and AIDS, with nearly 181,000 of those resulting in death.

8 Mar 2018

Boosting the brain's immune cells may prevent or reduce severity of Alzheimer's disease

Sanford Burnham Prebys Medical Research Institute researchers have published two new studies in Neuron that describe how TREM2, a receptor found on immune cells in the brain, interacts with toxic amyloid beta proteins to restore neurological function.

8 Mar 2018

High-resolution fMRI provides clues about age-related memory differences

As we get older, it's not uncommon to experience "senior moments," in which we forget where we parked our car or call our children by the wrong names. And we may wonder: Are these memory lapses a normal part of aging, or do they signal the early stages of a severe disorder such as Alzheimer's disease? Currently, there's no good way to tell.

8 Mar 2018

Survival of transplant candidates found to be better than predicted by BODE score

COPD remains the leading indication for lung transplantation worldwide and accounts for one third of all lung transplants performed.

7 Mar 2018

Research identifies new biomarkers for future dementia risk

Sudha Seshadri, M.D., founding director of the Glenn Biggs Institute for Alzheimer's & Neurodegenerative Diseases at UT Health San Antonio, is co-leader and senior author on research announced March 6 that identifies novel biomarkers of risk for future dementia.

6 Mar 2018

Study findings establish basis for epigenetic link between aging and Alzheimer's disease

Although certain genetic variants increase the risk of Alzheimer's disease (AD), age is the strongest known risk factor. But the way in which molecular processes of aging predispose people to AD, or become impaired in AD remains a mystery.

6 Mar 2018

Treatments targeted to enhance brain neurotrophic factor signaling may improve memory functions

Treatments targeted to enhance brain neurotrophic factor signaling could improve memory functions in Alzheimer's disease even though they don't alter brain amyloid burden, according to recent research from the University of Eastern Finland.

6 Mar 2018

UNC Lineberger study identifies genetic clues that explain how breast cancer metastasizes

Breast cancer is the second leading cause of cancer death in women in the United States, with most deaths caused by the cancer spreading beyond the breast.

6 Mar 2018

Study unlocks big puzzle in familial breast cancer

Mutations in known breast cancer genes such as BRCA1 and BRCA2 are identified in only approximately 20 per cent of women who are offered genetic testing for familial breast cancer.

1 Mar 2018

InSysBio evaluates tau protein phosphorylation related targets for treatment of AD

InSysBio continues to investigate the mechanisms underlying Alzheimer's disease using the quantitative systems pharmacology modeling approach. The part of QSP model describing tau protein was published in the PLOS ONE journal. This is one of more than dozen InSysBio publications in AD area during last seven years.

28 Feb 2018

New treatment shows promise to fight against serious inflammatory disease

Still's disease is a serious orphan disease manifested by high fevers, skin and joint involvement, including paralysis, as well as damage to other organs such as the liver or spleen. It is caused by a deregulation of the immune system triggering an acute inflammatory response.

27 Feb 2018

Scientists map breast cancer's spread routes

Breast cancer spreads to other organs in the body according to certain specific patterns. This has been shown by a team of researchers from Karolinska Institutet and KTH in Sweden and the University of Helsinki in Finland who have mapped breast cancer's spread routes in patients by studying the cancer cells' DNA. The study is published in The Journal of Clinical Investigation.

27 Feb 2018

K2M announces licensure of BACS Data Management tool to ISSGF

K2M Group Holdings, Inc., a global leader of complex spine and minimally invasive solutions focused on achieving three-dimensional Total Body Balance™, today announced the licensure of its BACS® Data Management tool to the International Spine Study Group Foundation for collecting spine patient data, including patient-reported outcome measures, as part of the ISSGF’s globally recognized research studies.

27 Feb 2018

Vitamin D cannot be metabolized without sufficient magnesium levels, review finds

There is a caveat to the push for increased Vitamin D: Don't forget magnesium. A review published in The Journal of the American Osteopathic Association found Vitamin D can't be metabolized without sufficient magnesium levels, meaning Vitamin D remains stored and inactive for as many as 50 percent of Americans.

26 Feb 2018

New research project to determine why mine dust-related lung diseases are on the rise

The passage of critical mine health and safety legislation in the late 1960s, along with advances in technology and safety practices, helped to decrease the prevalence of lung diseases for miners. But starting in the mid-1990s, there was a significant documented increase in lung diseases among coal workers, especially among younger workers.

24 Feb 2018

Pathology News and Research

Further Reading

World’s most common curable STI disproportionately affects black community, study finds

Study highlights divergent molecular mechanisms contributing to depression in men and women

Precision oncology may improve overall survival, lower healthcare costs for advanced cancer patients

Study highlights potential of ASO therapy to treat Fuchs endothelial corneal dystrophy patients

TSRI researchers show path to developing treatments for Charcot-Marie-Tooth disease

New study examines origin of cryptococcosis within the central nervous system

Boosting the brain's immune cells may prevent or reduce severity of Alzheimer's disease

High-resolution fMRI provides clues about age-related memory differences

Survival of transplant candidates found to be better than predicted by BODE score

Research identifies new biomarkers for future dementia risk

Study findings establish basis for epigenetic link between aging and Alzheimer's disease

Treatments targeted to enhance brain neurotrophic factor signaling may improve memory functions

UNC Lineberger study identifies genetic clues that explain how breast cancer metastasizes

Study unlocks big puzzle in familial breast cancer

InSysBio evaluates tau protein phosphorylation related targets for treatment of AD

New treatment shows promise to fight against serious inflammatory disease

Scientists map breast cancer's spread routes

K2M announces licensure of BACS Data Management tool to ISSGF

Vitamin D cannot be metabolized without sufficient magnesium levels, review finds

New research project to determine why mine dust-related lung diseases are on the rise

Industry Focus eBook - Analytical Chemistry (2nd Edition) eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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