Adenovirus News and Research

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Adenoviruses most commonly cause respiratory illness; however, depending on the infecting serotype, they may also cause various other illnesses, such as gastroenteritis, conjunctivitis, cystitis, and rash illness. Symptoms of respiratory illness caused by adenovirus infection range from the common cold syndrome to pneumonia, croup, and bronchitis. Patients with compromised immune systems are especially susceptible to severe complications of adenovirus infection. Acute respiratory disease (ARD), first recognized among military recruits during World War II, can be caused by adenovirus infections during conditions of crowding and stress.

Overcoming Challenges of Assays of Complex Cellular Models with Real-Time Live-Cell Analysis

There's a continued drive towards making in vitro assays ever more translational towards in vivo models and ultimately the clinic. This ties in with the resurgence of phenotypic screening and is a response to the perceived poor translation of the traditional simple cell-based assays, often developed to study just single protein targets.

From Sartorius 5 Dec 2017

Researchers test new vaccination strategy against HIV-related SIV in monkeys

According to the WHO, there are currently more than 36 million people infected with the human immunodeficiency virus (HIV) and a further 2.4 million become infected every year.

15 Nov 2017

Researchers to test use of ‘viral specific’ T-cells to target toxic viruses in children

Michael Pulsipher, MD, of the Children's Center for Cancer and Blood Diseases at Children's Hospital Los Angeles, along with Michael Keller, MD from Children's National Health System in Washington, DC, have been awarded $4.8 million by the California Institute for Regenerative Medicine to study the use of a new T-cell therapy to help fight active viral infections in children with severe immune deficiencies.

7 Nov 2017

Ebola vaccine that provides a year’s worth of protection developed

Liberia’s Ebola outbreak has yielded a successful trial of two vaccines against the deadly infection that could provide protection for up to a year and is also deemed to be safe.

12 Oct 2017

Sartorius Stedim Biotech launches new Sartobind Cassettes for commercial applications

Sartorius Stedim Biotech, a leading international supplier for the biopharmaceutical industry, has expanded its range of single-use membrane chromatography solutions with Sartobind Cassettes.

From Sartorius 11 Sep 2017

Researchers identify important adenovirus receptor in macrophages of mice

Adenoviral infections have a mild disease progression in healthy people, but it can be dangerous for immunocompromised people.

24 Aug 2017

Viruses live in our environment year-round, UCLA specialist says

Summer colds might seem rare, but you're actually just as likely to catch one in the summer as in the winter. Why? "Viruses don't take vacations; they live our environment year-round," explains Dr. Michael Cohen, infectious disease specialist at UCLA Health-Santa Clarita.

10 Jul 2017

JAX researchers explore how dendritic cells promote adaptive immunity to virus

A research team led by Jackson Laboratory Professor Karolina Palucka, M.D., Ph.D., in collaboration with a research team at Institut Curie in France led by Dr. Nicolas Manel, have addressed a long-standing puzzle of immunology: How do dendritic cells (DCs) do their job of promoting adaptive immunity to a virus while avoiding getting infected themselves?

7 Jul 2017

Study opens the lid on overprescribing of antibiotics for acute conjunctivitis

A new study suggests that most people with acute conjunctivitis, or pinkeye, are getting the wrong treatment.

29 Jun 2017

Researchers uncover structural details that make eye-targeting virus a better tool for future therapies

In their quest to replicate themselves, viruses have gotten awfully good at tricking human cells into pumping out viral proteins. That's why scientists have been working to use viruses as forces for good: to deliver useful genes to human cells and help patients who lack important proteins or enzymes.

12 May 2017

Latest advances in antibody delivery mediated by rAAV for treatment of chronic and infectious diseases

Monoclonal antibody-based therapies have revolutionized treatments of cancer and autoimmune diseases because of their specificity and limited toxicity.

21 Apr 2017

Innovative strategy uses genetically modified viruses to selectively attack tumor cells

Scientists at the IDIBAPS Biomedical Research Institute and at the Institute for Research in Biomedicine lead a study in which they have designed a new strategy to get genetically modified viruses to selectively attack tumor cells without affecting healthy tissues.

16 Mar 2017

Study: Investigational Ebola vaccine regimen induced immune response that persisted for one year

A two-vaccine regimen intended to protect against Ebola virus disease induced an immune response that persisted for approximately one year in healthy adult volunteers, according to results from a Phase 1 clinical trial published in the March 14th issue of the Journal of the American Medical Association.

15 Mar 2017

New study examines immune responses to Ebola vaccines at one year after immunization

Immune responses to Ebola vaccines at one year after vaccination are examined in a new study appearing in the March 14 issue of JAMA.

14 Mar 2017

Study: More than ten million lives saved by discovery of cell strain in 1962

Nearly 200 million cases of polio, measles, mumps, rubella, varicella, adenovirus, rabies and hepatitis A -- and approximately 450,000 deaths from these diseases -- were prevented in the U.S. alone between 1963 and 2015 by vaccination, researchers estimate.

3 Mar 2017

IDIBELL scientists develop oncolytic virus capable of redirecting immune system to attack cancer cells

Researchers of the Cancer Virotherapy Research Group of Bellvitge Biomedicine Research Institute, led by Dr. Ramon Alemany, have developed an oncolytic virus capable of redirecting the patient's immune system against their tumor cells.

16 Feb 2017

Researchers identify molecular signatures to predict efficacy of malaria vaccines

The acid test for a vaccine is: "Does it protect people from infection?" Emory Vaccine Center researchers have analyzed this issue for a leading malaria vaccine called RTS,S, and their results have identified candidate signatures, or biomarkers, in the blood of vaccinated subjects which predict the likelihood of success from vaccination.

13 Feb 2017

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