Precision Medicine News and Research

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What drives insulin resistance? Proteomics reveals key pathways in human skeletal muscle

Identifying proteomic signatures of insulin resistance in fasting muscle offers insights for personalized type 2 diabetes therapies based on molecular profiles.

30 May 2025

Alcohol abuse drug may mitigate trauma-induced damage, especially in females

Runaway cell death and inflammation triggered by severe trauma may be interrupted by a drug used to prevent alcohol abuse – and it may be particularly effective in females, according to new research led by University of Pittsburgh School of Medicine surgeon-scientists and published today in Science Translational Medicine.

28 May 2025

Maternal warmth in early childhood shapes health through social safety

Parental warmth and affection in early childhood can have life-long physical and mental health benefits for children, and new UCLA Health research points to an important underlying process: children's sense of social safety.

28 May 2025

Firmicutes bacteria can help maintain bone mass, study suggests

A recent study involving 684 Chinese adults has uncovered a significant connection between gut microbiota, aging, and bone health, particularly in relation to osteoporosis, a condition that weakens bones and increases the risk of fractures.

27 May 2025

Scientists discover unique molecular fingerprints of insulin resistance

Scientists have unearthed surprising details about how our bodies handle insulin – the hormone that plays a crucial role in regulating blood sugar and developing diabetes.

27 May 2025

Metagenomic next-generation sequencing improves pulmonary infection diagnosis

A recent study on the application of Metagenomic next-generation sequencing (mNGS) found that mNGS can achieve early detection of pathogens and accelerate the development of targeted anti-infection treatment plans, thereby improving treatment outcomes and patient prognosis.

23 May 2025

Experimental ALS drug shows unprecedented recovery in some patients

When Columbia neurologist and scientist Neil Shneider speaks to his ALS patients who volunteer for experimental therapies, he's unwaveringly honest.

23 May 2025

Closed Loop Medicine appoints Kate Woolland as CEO

Closed Loop Medicine Ltd. (“CLM”), a leader in pharmaceutical precision dosing, today announced the appointment of Kate Woolland as Chief Executive Officer.

22 May 2025

Long noncoding RNA ESSENCE identified as key driver of colorectal cancer progression

Colorectal cancer (CRC) remains one of the most prevalent and deadly cancers worldwide, with rising incidence linked to dietary and lifestyle changes.

18 May 2025

Genomic study of non-Hispanic Black veterans with prostate cancer yields key insights for precision medicine

In the largest clinical genomic profiling study of non-Hispanic Black men with metastatic prostate cancer to date, researchers from Moffitt Cancer Center, University of Pennsylvania, University of California Los Angeles and the Veterans Affairs (VA) National Precision Oncology Program found key differences in tumor biology between non-Hispanic Black and non-Hispanic white veterans, but similar survival outcomes when both groups had equal access to care.

16 May 2025

Liquid biopsy advances precision medicine in gynecological cancers

A landmark review, now published in the Journal of Experimental & Clinical Cancer Research, offers a sweeping and authoritative synthesis on the use of liquid biopsy in gynecological oncology placing this emerging tool at the forefront of precision medicine for women.

16 May 2025

New gene editor evoCAST enables precise insertion of complete genes

Ask scientists what gene editing tool is most needed to advance gene therapy, and they'd probably describe a system that's now close to realization in the labs of Samuel Sternberg at Columbia University Vagelos College of Physicians and Surgeons and David Liu at the Broad Institute of MIT and Harvard.

15 May 2025

Two genetic variants linked to breast cancer discovered in black South African women

Genetic factors contribute to some 30% of breast cancer cases in SA, necessitating investment in genomic research in African contexts.

15 May 2025

Injecting medicine into amniotic fluid shows promise for treating genetic disorders

Injecting medicine into the amniotic fluid staves off progression of spinal muscular atrophy in utero.

14 May 2025

How 196,000 Spanish participants are helping decode heart disease risk

The CORDELIA study combines data from 35 Spanish cohorts (n = 196,632) to investigate genetic, clinical, and lifestyle risk factors for ASCVD in Southern Europe. It aims to conduct the region’s most comprehensive genome-wide association study and develop tailored risk prediction tools.

14 May 2025

HIV uses circular RNAs to evade immunity and boost replication

In a groundbreaking discovery, researchers from Florida Atlantic University's Charles E. Schmidt College of Medicine have identified a never-before-seen mechanism that enables the human immunodeficiency type 1 virus (HIV-1) to evade the body's natural defenses and use it to support its survival and replication.

13 May 2025

New treatment approach boosts survival rates for patients with aggressive, inherited breast cancers

A new treatment approach significantly improves survival rates for patients with aggressive, inherited breast cancers, according to Cambridge researchers.

13 May 2025

Study reveals key differences in health risks between males and females

The results of an international study led by researchers from Queen Mary University of London's Precision Healthcare University Research Institute (PHURI) shed new light the underlying biological mechanisms which cause differences in health risks, symptoms and outcomes between males and females.

13 May 2025

Review spotlights MYC as a multidimensional therapeutic target in cancer

A new review in Genes and Diseases explores the central role of MYC, a master regulatory protein, in the development and progression of cancer, spotlighting its potential as a multidimensional therapeutic target.

12 May 2025

Precision medicine approach improves treatment for soft tissue sarcomas

A study conducted by researchers from the Agency for Science, Technology and Research (A*STAR), National Cancer Centre Singapore (NCCS) and National University of Singapore (NUS), in collaboration with biotech company, KYAN Technologies, has demonstrated that a precision medicine approach improves treatment selection for patients with soft tissue sarcomas (STS) in a clinical setting.

7 May 2025

Precision Medicine News and Research

What drives insulin resistance? Proteomics reveals key pathways in human skeletal muscle

Alcohol abuse drug may mitigate trauma-induced damage, especially in females

Maternal warmth in early childhood shapes health through social safety

Firmicutes bacteria can help maintain bone mass, study suggests

Scientists discover unique molecular fingerprints of insulin resistance

Metagenomic next-generation sequencing improves pulmonary infection diagnosis

Experimental ALS drug shows unprecedented recovery in some patients

Closed Loop Medicine appoints Kate Woolland as CEO

Long noncoding RNA ESSENCE identified as key driver of colorectal cancer progression

Genomic study of non-Hispanic Black veterans with prostate cancer yields key insights for precision medicine

Liquid biopsy advances precision medicine in gynecological cancers

New gene editor evoCAST enables precise insertion of complete genes

Two genetic variants linked to breast cancer discovered in black South African women

Injecting medicine into amniotic fluid shows promise for treating genetic disorders

How 196,000 Spanish participants are helping decode heart disease risk

HIV uses circular RNAs to evade immunity and boost replication

New treatment approach boosts survival rates for patients with aggressive, inherited breast cancers

Study reveals key differences in health risks between males and females

Review spotlights MYC as a multidimensional therapeutic target in cancer

Precision medicine approach improves treatment for soft tissue sarcomas

Event guide: The 4th Precision Medicine in Inflammatory Bowel Disease Summit eBook

How ELRIG Is Helping Mid-Career Scientists Navigate Leadership, Career Change and Redundancy

The role of UV-Vis in biopharma QC

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