Therapeutics News and Research

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FDA-approved COVID-19 drug should be used cautiously, says UC researcher

While the world has its eyes on vaccines to stop the spread of coronavirus, therapeutics are still necessary to treat hospitalized patients. One of these treatments, remdesivir, is the first and only antiviral agent of its kind that the U.S. Food and Drug Administration (FDA) has approved so far for COVID-19.

3 Jan 2021

Researchers discover how chromosomal instability allows cancer cells to avoid immune defenses

Cancer cells are known for spreading genetic chaos. As cancer cells divide, DNA segments and even whole chromosomes can be duplicated, mutated, or lost altogether. This is called chromosomal instability, and scientists at Memorial Sloan Kettering have learned that it is associated with cancer's aggressiveness.

28 Dec 2020

Phase 3 trial of Novavax COVID-19 vaccine candidate begins enrolling volunteers

The Phase 3 trial of another investigational coronavirus disease 2019 (COVID-19) vaccine has begun enrolling adult volunteers.

28 Dec 2020

Study depicts previously unknown molecular mechanism underlying healthy brain development

A research team led by Michael Fox, a professor at the Fralin Biomedical Research Institute at VTC, has identified the type of brain cell that produces collagen 19, a protein that is crucial for the formation of inhibitory circuits in the brain.

21 Dec 2020

The weak spot of colon cancer stem cells

Colon cancer stem cells have one weak spot: the enzyme Mll1. An MDC team led by Walter Birchmeier has now shown in Nature Communications that blocking this protein prevents the development of new tumors in the body.

21 Dec 2020

Prior use of renin-angiotensin system inhibitors linked to reduced risk of death in older COVID-19 patients with hypertension

A new study, appearing as a preprint on the medRxiv* server, demonstrates the protective effect of drugs in older COVID-19 patients with hypertension.

21 Dec 2020

Autobahn Labs announces a strategic drug discovery partnership with UCSF

Autobahn Labs, a virtual incubator partnering with top academic and research institutions to catalyze early-stage drug discovery and development, today announced a strategic collaboration with the University of California San Francisco (UCSF).

21 Dec 2020

Researchers discover novel mechanism by which cells turn over mitochondria

Mitochondria are cellular organelles that generate most of the energy cells need to function, and thus play an important role in maintaining cell health.

21 Dec 2020

Research may lead to better treatment and vaccines for Ebola, COVID-19

In the midst of a global pandemic with COVID-19, it's hard to appreciate how lucky those outside of Africa have been to avoid the deadly Ebola virus disease.

21 Dec 2020

Novel SARS-CoV-2 neutralizing antibody enters Phase 1/2a clinical study

Cologne University Hospital (UKK), University of Marburg (UMR), the German Center for Infection Research (DZIF) and Boehringer Ingelheim today announced the initiation of Phase 1/2a clinical investigation of BI 767551, a new SARS-CoV-2 neutralizing antibody.

18 Dec 2020

Study paves the way to a potential new treatment for rare terminal childhood illness

Scientists at the University of Exeter have identified a way to "rescue" cells that have genetically mutated, paving the way to a possible new treatment for rare terminal childhood illness such as mitochondrial disease.

18 Dec 2020

CN Bio and University of Melbourne announce partnership focused on respiratory therapies for recovering COVID-19 patients

CN Bio, a leading cell culture company, that has developed single and multi-organ microphysiological systems (MPS) to improve the accuracy and efficiency of drug discovery, today announced a collaboration with the University of Melbourne, focused on respiratory therapies for recovering COVID-19 patients.

18 Dec 2020

Pig stem cells offer a new way to grow human organs for transplantation

In a new paper published in Stem Cell Reports, Bhanu Telugu and co-inventor Chi-Hun Park of the University of Maryland (UMD) Department of Animal and Avian Sciences show for the first time that newly established stem cells from pigs, when injected into embryos, contributed to the development of only the organ of interest (the embryonic gut and liver), laying the groundwork for stem cell therapeutics and organ transplantation.

18 Dec 2020

University of Ottawa earns 10 Canada research chairs covering a broad scope of subjects

The University of Ottawa has earned a total of 10 Canada Research Chairs (CRCs) covering a broad scope of subjects, from the exploration of disruptive impacts of stress on higher brain functions to the need to preserve Indigenous traditional cultural memories, and emerging computing technologies that pave the way to smart cities.

18 Dec 2020

Researchers are developing new criteria for clinical research of antiphospholipid syndrome

An international team of more than 80 collaborators led by Hospital for Special Surgery (HSS) investigators is developing new classification criteria for clinical research of antiphospholipid syndrome (APS), a life-threatening autoimmune clotting disorder.

17 Dec 2020

Regulating fas protein may be a route to prevent cancer relapse after immunotherapy

HDL nanoparticles prevent cholesterol movement at membrane receptor to inhibit entry of SARS-CoV-2 pseudovirus in cell culture

As researchers strive to find safe therapeutics for COVID 19, a study suggests that preventing the movement of cholesterol may inhibit viral entry by up to 80%.

17 Dec 2020

Therapeutics News and Research

FDA-approved COVID-19 drug should be used cautiously, says UC researcher

Researchers discover how chromosomal instability allows cancer cells to avoid immune defenses

Phase 3 trial of Novavax COVID-19 vaccine candidate begins enrolling volunteers

Study depicts previously unknown molecular mechanism underlying healthy brain development

The weak spot of colon cancer stem cells

Prior use of renin-angiotensin system inhibitors linked to reduced risk of death in older COVID-19 patients with hypertension

Autobahn Labs announces a strategic drug discovery partnership with UCSF

Researchers discover novel mechanism by which cells turn over mitochondria

Research may lead to better treatment and vaccines for Ebola, COVID-19

Novel SARS-CoV-2 neutralizing antibody enters Phase 1/2a clinical study

Study paves the way to a potential new treatment for rare terminal childhood illness

CN Bio and University of Melbourne announce partnership focused on respiratory therapies for recovering COVID-19 patients

Pig stem cells offer a new way to grow human organs for transplantation

University of Ottawa earns 10 Canada research chairs covering a broad scope of subjects

Researchers are developing new criteria for clinical research of antiphospholipid syndrome

Regulating fas protein may be a route to prevent cancer relapse after immunotherapy

MFCR awards new grants to support an emerging approach to cancer therapeutics

BU researchers awarded $2.4 million NIH grant to study idiopathic pulmonary fibrosis

WEHI researchers suggest potential new approach to treat stomach cancer

HDL nanoparticles prevent cholesterol movement at membrane receptor to inhibit entry of SARS-CoV-2 pseudovirus in cell culture

Industry Focus eBook - Biotechnology (4th edition) eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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