Pathology News and Research

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Pathology is the study and diagnosis of disease through examination of organs, tissues, bodily fluids, and whole bodies (autopsies). The term also encompasses the related scientific study of disease processes, called General pathology. Medical pathology is divided in two main branches, Anatomical pathology and Clinical pathology. Veterinary pathology is concerned with animal disease whereas Phytopathology is the study of plant diseases.

New HSS study may signal hope for patients suffering from scleroderma

Scleroderma is a terribly debilitating disease with no effective treatments and the mortality rates are still upwards of 20%-50%, the highest of any rheumatic disease.

11 Jan 2018

Human cardiac-muscle patches improve recovery from heart attack injury

Large, human cardiac-muscle patches created in the lab have been tested, for the first time, on large animals in a heart attack model. This clinically relevant approach showed that the patches significantly improved recovery from heart attack injury.

11 Jan 2018

Clinical study investigates lifestyle biomarkers in prostate cancer survivors

Advanced glycation end products, which have been linked to many chronic diseases, including diabetes, cardiovascular disease and cancer, build up in the body from birth due to normal metabolism but are often higher in those eating the high-fat, high-sugar, highly processed foods characteristic of the Western diet.

11 Jan 2018

Kessler Foundation researcher receives grant for study on emotional processing intervention in MS

Helen Genova, PhD, Assistant Director of Neuropsychology & Neuroscience Research at Kessler Foundation, has been awarded a $44,000 grant from the National Multiple Sclerosis Society.

10 Jan 2018

Biomarkers may help predict prognosis of gastric cancer patients with alcohol consumption habits

Alcohol consumption has been identified as a modifiable risk factor for cancers such as gastric cancer. A new report in the The American Journal of Pathology sheds light on how specific proteins interact with alcohol, and how that interplay impacts survival and response to platinum-based adjuvant chemotherapy in patients with gastric cancer who may or may not still be drinking.

10 Jan 2018

CHOP researchers explore effective nutritional therapies for mitochondrial disease

Defects in mitochondria, the tiny structures that power our cells by functioning as biological batteries, cause an array of complex, often life-threatening disorders that can affect any and all organs and systems.

10 Jan 2018

UC scientists identify protein that acts as mediator of HER2-driven breast cancer

Researchers at the University of Cincinnati College of Medicine have identified for the first time that the estrogen receptor-binding protein MED1 is a critical mediator of HER2-driven breast cancer, identifying it as a potential therapeutic target.

9 Jan 2018

New way to identify breast cancer patients who may develop incurable secondary tumors

Scientists from King's College London, funded by Breast Cancer Now, believe they have found a way to identify lymph-node positive breast cancer patients who are most likely to develop incurable secondary tumours (metastases) and those who are less at risk.

9 Jan 2018

Researchers develop drug that supports cellular traffic jam theory in ALS/FTD

Neurodegeneration in ALS/FTD may be caused by TDP-43 aggregation in the cytoplasm, causing cellular traffic jams. The trial drug can sequester TDP-43.

9 Jan 2018

Choosing The Correct Camera for Fluorescence Microscopy

It is important to select the proper camera for fluorescence microscopy which has high sensitivity and low noise, to avoid photo bleaching your sample. A monochrome camera is also preferred for fluorescence imaging because it does not have a color filter pattern superimposed over the image sensor. Since the microscope’s filter wheel selects which wavelength makes its way to the sensor, a monochrome camera allows equal signal detection on all pixels and increases the overall sensitivity of the camera.

9 Jan 2018

Study finds common contraceptive shot may increase HIV risk

A recent study found an association between HIV risk and the use of the common birth control medications DMPA, among women from sub-Saharan Africa.

9 Jan 2018

Scientists use artificial intelligence to create new ‘ImmunoMap’

Johns Hopkins scientists have used a form of artificial intelligence to create a map that compares types of cellular receptors, the chemical "antennas" on the surface of immune system T-cells.

8 Jan 2018

Targeted fluorescence successfully identifies pulmonary metastases in osteosarcoma patient

In a proof-of-principle case report, researchers announce that targeted fluorescence successfully identified pulmonary metastases in a patient with osteosarcoma, making it easier for surgeons to locate the tumors for resection.

5 Jan 2018

Adrenomedullin could serve as biomarker, therapeutic target in disorders caused by leaky blood vessels

Disorders caused by a leaky vasculature are more common than most people think. Despite ICU treatment, one third of the 27 million patients globally that suffer from sepsis, and up to 20% of the more than 5 million US patients with congestive heart failure die every year from their condition.

5 Jan 2018

Newly identified germline variations increase risk of relapse or second cancers in leukemia patients

Newly identified germline variations in a key tumor suppressor gene predispose individuals to develop leukemia as children and leave them with a 1-in-4 chance of developing a second cancer later. St. Jude Children's Research Hospital scientists led the study, which appears today in the Journal of Clinical Oncology.

5 Jan 2018

Pathology News and Research

Further Reading

New HSS study may signal hope for patients suffering from scleroderma

Human cardiac-muscle patches improve recovery from heart attack injury

Clinical study investigates lifestyle biomarkers in prostate cancer survivors

Kessler Foundation researcher receives grant for study on emotional processing intervention in MS

Biomarkers may help predict prognosis of gastric cancer patients with alcohol consumption habits

CHOP researchers explore effective nutritional therapies for mitochondrial disease

UC scientists identify protein that acts as mediator of HER2-driven breast cancer

New way to identify breast cancer patients who may develop incurable secondary tumors

Researchers develop drug that supports cellular traffic jam theory in ALS/FTD

Choosing The Correct Camera for Fluorescence Microscopy

Study finds common contraceptive shot may increase HIV risk

Scientists use artificial intelligence to create new ‘ImmunoMap’

Targeted fluorescence successfully identifies pulmonary metastases in osteosarcoma patient

Adrenomedullin could serve as biomarker, therapeutic target in disorders caused by leaky blood vessels

Newly identified germline variations increase risk of relapse or second cancers in leukemia patients

Study provides insight into how early-stage breast cancer progresses to invasive ductal carcinoma

TriNetX reveals Natural Language Processing to Better Identify Patients for Clinical Trials

Japanese researchers propose new diagnostic criteria and treatment guidelines for thyroid storm

Blueberry extract can enhance effectiveness of cervical cancer treatment

Selenium protects specialized neurons from cell death during postnatal development

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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