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Insulin levels affect the brain's dopamine systems

Insulin, long known as an important regulator of blood glucose levels, now has a newly appreciated role in the brain.

18 Oct 2007

In vitro models will minimize animal use in arthritis studies

It's hard to think of scientists in laboratories working toward solutions for medical problems without mice or other laboratory animals, but animals' roles in at least one major research laboratory may soon be minimal.

18 Oct 2007

Phase II map of human genetic variation

The International HapMap Consortium today published analyses of its second-generation map of human genetic variation, which contains three times more markers than the initial version unveiled in 2005.

18 Oct 2007

Benefit of exenatide has not yet been proven

Since May 2007, a new drug has been available for the treatment of patients with diabetes mellitus type 2 in Germany: exenatide (trade name: Byetta), which is marketed by the manufacturer Eli Lilly.

18 Oct 2007

Scientists discover how HIV evolves

University of Florida scientists have discovered how HIV evolves over the course of a person's lifetime into a more deadly form that heralds the onset of full-blown AIDS.

17 Oct 2007

New therapy for chronic spasticity and rigidity

Research led by scientists at the University of California, San Diego (UCSD) School of Medicine has identified a target with potential as an effective new therapy for chronic spasticity and rigidity, a painful condition that often results from spinal cord injury.

17 Oct 2007

Technology to beat superbugs wins major funding

Scientists at Biocontrol, leading the world in developing new treatments to cure serious antibiotic-resistant infections, have secured a £250,000 investment from The Capital Fund.

17 Oct 2007

Taxol-type drugs give slight boost to survival rates in early breast cancer

The breast cancer drugs called taxanes, which include Taxol (paclitaxel) and Taxotere (docetaxel), increase survival rates when used as part of chemotherapy following surgery for cancers that have not spread, according to a new review of the research.

17 Oct 2007

Breakbone fever a growing public health threat

Dengue fever, known as “breakbone fever” because of the excruciating back and joint pain that accompanies this infectious disease, is a growing public health threat for people living in tropical countries, as well as travelers to destinations such as Thailand, Brazil and Puerto Rico, according to research being presented at the annual meeting of the American Society of Tropical Medicine and Hygiene (ASTMH), Nov. 4-7.

17 Oct 2007

Existing drugs may be useful in treating brain tumors

Scientists have shown how developing brain tumors can turn an encounter with a signaling molecule from a fatal experience for the tumor cells into a cue for their own growth and multiplication.

17 Oct 2007

Little difference in risk rates for angioplasty, bypass procedures

Patients with heart disease who undergo coronary angioplasty have an equivalent risk of death and heart attack as patients who undergo coronary bypass surgery, according to Stanford University School of Medicine researchers.

17 Oct 2007

Severely mentally ill at high risk for cardiovascular disease

A psychiatrist at Washington University School of Medicine in St. Louis writes in the Journal of the American Medical Association (JAMA) that although mortality from cardiovascular disease has declined in the United States over the past several decades, patients with severe psychiatric illness are not enjoying the benefits of that progress.

17 Oct 2007

Oral antibiotics effective to treat severe urinary tract infections

Although doctors routinely use IV antibiotics to cure patients with severe urinary tract infections (UTI), a new review from suggests that oral antibiotics work just as well - from treating acute symptoms to preventing long-term complications of UTI.

17 Oct 2007

Blood modulates how neurons process information

MIT scientists propose that blood may help us think, in addition to its well-known role as the conveyor of fuel and oxygen to brain cells.

17 Oct 2007

Mental disorders are disorders of the brain

Depression, anxiety disorders such as panic disorder and obsessive-compulsive disorders, alcohol and drug dependence, dementia and Parkinson's disease are just a few examples of "disorders of the brain".

17 Oct 2007

One-third of patients receiving HIV medication in Africa don't continue treatment

More than one-third of patients receiving HIV medication in Africa die or discontinue their treatment within two years, according to a study published in PLoS Medicine.

17 Oct 2007

Long-term high-dose ibuprofen slows the rate of decline in lung function in children with cystic fibrosis

The most important clinical problem for people with cystic fibrosis (CF) is inflammation of their lungs.

17 Oct 2007

Findings could lead to new therapy for spinal cord injury

17 Oct 2007

FDA approves raltegravir new HIV drug

The U.S. Food and Drug Administration (FDA) has approved raltegravir tablets for treatment of Human Immunodeficiency Virus (HIV)-1 infection in combination with other antiretroviral agents in treatment-experienced adult patients who have evidence of viral replication and HIV-1 strains resistant to multiple antiretroviral agents.

17 Oct 2007

Ear infection superbug found to be resistant to all pediatric antibiotics

Researchers have discovered a strain of bacteria resistant to all approved drugs used to fight ear infections in children, according to an article to be published tomorrow in the Journal of the American Medical Association (JAMA).

17 Oct 2007