Pathology News and Research

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Pathology is the study and diagnosis of disease through examination of organs, tissues, bodily fluids, and whole bodies (autopsies). The term also encompasses the related scientific study of disease processes, called General pathology. Medical pathology is divided in two main branches, Anatomical pathology and Clinical pathology. Veterinary pathology is concerned with animal disease whereas Phytopathology is the study of plant diseases.

Changes in microbiome due to antibiotic exposure may increase risk for inflammatory bowel disease

Exposure to antibiotics in mothers may increase risk for inflammatory bowel diseases in their offspring. This is the finding of a study in mice led by researchers from NYU School of Medicine and published Nov. 27 in the journal Nature Microbiology.

27 Nov 2017

Immune system plays key role in amount of osteoarthritic pain and progression

The immune system plays a pivotal role in the amount of pain and disease progression experienced by patients with osteoarthritis (OA), McMaster University researchers have found.

27 Nov 2017

Virus Painting, Lipids and Single Particle Charge

Various viral infections still pose a great threat to human and animal health. A wide range of viral species are surrounded by a lipid shell, the envelope, containing viral and cellular proteins.

From Izon Science 27 Nov 2017

High levels of natural immune suppressor in leukemia patients linked to poor survival

Patients diagnosed with the most common form of leukemia who also have high levels of an enzyme known to suppress the immune system are most likely to die early, researchers say.

27 Nov 2017

Researchers convert natural bacterial immune system into microscopic data recorder

Through a few clever molecular hacks, researchers at Columbia University Medical Center have converted a natural bacterial immune system into a microscopic data recorder, laying the groundwork for a new class of technologies that use bacterial cells for everything from disease diagnosis to environmental monitoring.

23 Nov 2017

Creutzfeldt-Jakob disease patients harbor infectious prions in their skin

Creutzfeldt-Jakob disease (CJD)- the human equivalent of mad cow disease- is caused by rogue, misfolded protein aggregates termed prions, which are infectious and cause fatal damages in the patient's brain. CJD patients develop signature microscopic sponge-like holes in their brains.

23 Nov 2017

Small protein modification can trigger invasive properties of prostate cancer cells, research finds

A small protein modification can trigger the aggressive migratory and invasive properties of prostate cancer cells, according to new research published on the cover of Oncotarget. The findings give greater insight into how cancers can move from one location in the body to another, and could help develop more effective therapies in the future.

22 Nov 2017

UCLA researchers reconstruct holograms, enhance optical microscopy using deep learning approach

A form of machine learning called deep learning is one of the key technologies behind recent advances in applications like real-time speech recognition and automated image and video labeling.

22 Nov 2017

Alzheimer's Tau protein interacts with cell membranes and forms toxic complexes

The brains of patients with Alzheimer's disease contain characteristic tangles inside neurons. These tangles are formed when a protein called Tau aggregates into twisted fibrils. As a result, the neurons' transport systems disintegrate, essential nutrients can't move through, and the cells begin to die, affecting the brain's functions and giving rise to the disease's symptoms.

22 Nov 2017

Oncologists find new biomarker for breast cancer having poor prognosis

With the support of the FWF, an oncologist found a biomarker for breast cancer having a poor prognosis and developed two viable methods to detect it in tissue samples.

22 Nov 2017

Analysis of aged brains reveals new details about Alzheimer's disease and dementia

In a comprehensive analysis of samples from 107 aged human brains, researchers at the Allen Institute for Brain Science, UW Medicine and Kaiser Permanente Washington Health Research Institute have discovered details that will help researchers better understand the biological bases for Alzheimer's disease and dementia in older populations.

21 Nov 2017

Scientists develop novel technology that uses CRISPR to map genetic mutations

A team of scientists led by Virginia Commonwealth University physicist Jason Reed, Ph.D., have developed new nanomapping technology that could transform the way disease-causing genetic mutations are diagnosed and discovered.

21 Nov 2017

Study shows how naïve T-cells may affect tumor immunity and immunotherapy

The immune cells that are trained to fight off the body's invaders can become defective. It's what allows cancer to develop. So most research has targeted these co-called effector T-cells.

17 Nov 2017

Old World monkeys could hold key to stop progression of rheumatoid arthritis

In the quest for a new and more effective treatment for rheumatoid arthritis, researchers from the Keck School of Medicine of USC looked to a primate that mostly roams the land in Asia, the Middle East and Africa.

17 Nov 2017

Researchers identify possible genetic basis for coronary artery disease

The buildup of plaque in the heart's arteries is an unfortunate part of aging. But by studying the genetic makeup of people who maintain clear arteries into old age, researchers led by UNC's Jonathan Schisler, PhD, have identified a possible genetic basis for coronary artery disease (CAD), as well as potential new opportunities to prevent it.

17 Nov 2017

New model to test effectiveness of existing and potential CF therapies

UNC School of Medicine researchers have developed a new laboratory model of the infection- and inflammation-plagued airways of cystic fibrosis (CF) patients.

17 Nov 2017

Scientists unveil pathology underlying optic nerve hypoplasia in children

Scientists at the Virginia Tech Carilion Research Institute (VTCRI) have revealed the pathology of cells and structures stricken by optic nerve hypoplasia, a leading cause of childhood blindness in developed nations.

16 Nov 2017

Discovery of natural molecule could lead to effective treatments for gum disease and atherosclerosis

Resolvin E1, a molecule produced naturally in the body from an omega -3 fish oil, topically applied on gum tissues not only prevents and treats gum disease as previously shown (Hasturk et al 2006 and 2007), but also decreases the likelihood for advanced arterial atherosclerotic plaques to rupture and form a dangerous thrombus or blood clot.

16 Nov 2017

Heart injury triggers irreversible dysregulation that alters cardiosplenic and cardiorenal networks

Heart failure after a heart attack is a global epidemic leading to chronic heart failure pathology. About 6 million people in the United States and 23 million worldwide suffer from this end-stage disease.

15 Nov 2017

Synthetic double-stranded RNA may have potential for use as vaccine to prevent liver cancer

Primary liver cancer is now the second leading cause of cancer-related death worldwide, and its incidences and mortality are increasing rapidly in the United Stated. In late stages of the malignancy, there are no effective treatments or drugs.

14 Nov 2017

Pathology News and Research

Further Reading

Changes in microbiome due to antibiotic exposure may increase risk for inflammatory bowel disease

Immune system plays key role in amount of osteoarthritic pain and progression

Virus Painting, Lipids and Single Particle Charge

High levels of natural immune suppressor in leukemia patients linked to poor survival

Researchers convert natural bacterial immune system into microscopic data recorder

Creutzfeldt-Jakob disease patients harbor infectious prions in their skin

Small protein modification can trigger invasive properties of prostate cancer cells, research finds

UCLA researchers reconstruct holograms, enhance optical microscopy using deep learning approach

Alzheimer's Tau protein interacts with cell membranes and forms toxic complexes

Oncologists find new biomarker for breast cancer having poor prognosis

Analysis of aged brains reveals new details about Alzheimer's disease and dementia

Scientists develop novel technology that uses CRISPR to map genetic mutations

Study shows how naïve T-cells may affect tumor immunity and immunotherapy

Old World monkeys could hold key to stop progression of rheumatoid arthritis

Researchers identify possible genetic basis for coronary artery disease

New model to test effectiveness of existing and potential CF therapies

Scientists unveil pathology underlying optic nerve hypoplasia in children

Discovery of natural molecule could lead to effective treatments for gum disease and atherosclerosis

Heart injury triggers irreversible dysregulation that alters cardiosplenic and cardiorenal networks

Synthetic double-stranded RNA may have potential for use as vaccine to prevent liver cancer

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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