Pathology News and Research

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Pathology is the study and diagnosis of disease through examination of organs, tissues, bodily fluids, and whole bodies (autopsies). The term also encompasses the related scientific study of disease processes, called General pathology. Medical pathology is divided in two main branches, Anatomical pathology and Clinical pathology. Veterinary pathology is concerned with animal disease whereas Phytopathology is the study of plant diseases.

Scientists identify critical player in Alzheimer's disease pathogenesis

Scientists at Sanford Burnham Prebys Medical Discovery Institute have shown that a protein called membralin is critical for keeping Alzheimer's disease pathology in check.

14 Nov 2017

Researchers use novel computational tool to understand complex disease processes

Hypertension and heart disease arise from many contributing and interacting factors: genetics, food, and exercise, as well as problems with heart, liver, or kidney function.

14 Nov 2017

Breastfeeding may increase hay fever and eczema risk, but does not have clear effect on asthma

The effect of breastfeeding on the risk of developing asthma and allergy has been debated for a long time. In a recent study, Uppsala University researchers show that breastfeeding might in fact increase the risk of developing hay fever and eczema, while not having any clear effect on the risk of asthma.

13 Nov 2017

Scientists develop novel mouse model to capture pathology of sporadic ALS and FTD

Neurodegenerative diseases are incurable and debilitating conditions that result in progressive degeneration and death of nerve cells, which leads to problems with movement or mental functioning. Examples include Alzheimer's, Parkinson's, amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD).

13 Nov 2017

Scientists identify new genes needed by Streptococcus pyogenes to grow in human saliva

Scientific and veterinary research charity, the Animal Health Trust, in partnership with world-leading scientists at the Houston Methodist Research Institute, have identified new genes linked to how, Streptococcus pyogenes, an important cause of human disease, survives in people.

13 Nov 2017

OSA may put elderly people at increased risk of developing Alzheimer's disease

Obstructive sleep apnea (OSA) may put elderly people at greater risk of developing Alzheimer's disease (AD), according to new research published online in the American Thoracic Society's American Journal of Respiratory and Critical Care Medicine.

10 Nov 2017

Common genetic fusion event could help identify patients with low-risk prostate cancer

Establishing the way in which a genetic alteration called a TMPRSS2-ERG gene fusion forms in a prostate cancer, rather than the presence of the gene fusion itself, could help identify patients with prostate cancer with a low risk of spreading, which might determine the best course of treatment for the patient.

10 Nov 2017

Scientists to investigate potential role of airborne pollutants as triggers of Parkinson's disease

The Department of Defense has awarded a multi-institutional team of scientists a series of grants totaling $4.37 million to investigate the potential role of airborne pollutants as triggers of Parkinson's disease via the nose.

9 Nov 2017

Novel mathematical model can predict how cancer patient will benefit from immunotherapies

Researchers at the Icahn School of Medicine at Mount Sinai have created the first mathematical model that can predict how a cancer patient will benefit from certain immunotherapies, according to a study published in Nature.

9 Nov 2017

Research suggests link between heart function and brain region critical for memory processing

Research by a team of Vanderbilt University Medical Center scientists suggests that older people whose hearts pump less blood have blood flow reductions in the temporal lobe regions of the brain, where Alzheimer's pathology first begins.

9 Nov 2017

Chronic liver inflammation promotes cancer by suppressing immunosurveillance, study finds

Chronic inflammation is known to drive many cancers, especially liver cancer. Researchers have long thought that's because inflammation directly affects cancer cells, stimulating their division and protecting them from cell death.

8 Nov 2017

Early intervention may be crucial to successful treatment of Friedreich's ataxia

New research published today in Disease Models & Mechanisms indicates that early intervention should be a key target in the development of new therapeutics for Friedreich's ataxia, as current treatments may be administered too late to target the disease effectively.

8 Nov 2017

Penn Medicine to conduct Northeast’s first clinical trial of uterine transplants

Penn Medicine will conduct the Northeast's first clinical trial of uterine transplants, to provide women with Uterine Factor Infertility (UFI) - an irreversible form of female infertility that affects as many as 5 percent of women worldwide and 50,000 women in the United States - with a new path to parenthood.

7 Nov 2017

Study finds link between increased brain glucose levels and Alzheimer's

A new study published yesterday in Alzheimer's & Dementia: the Journal of the Alzheimer's Association, found a link for the first time between abnormalities in the mechanism of glucose breakdown in the brain and the severity of tangles and amyloid plaques in the brain, as well as the commencement of visible symptoms of Alzheimer's disease.

7 Nov 2017

Immune system plays surprising role in the aftermath of heart attacks, study finds

A study led by Kevin King, a bioengineer and physician at the University of California San Diego, has found that the immune system plays a surprising role in the aftermath of heart attacks. The research could lead to new therapeutic strategies for heart disease.

7 Nov 2017

McMaster study: High-risk sexual behavior among women may increase risk of acquiring STIs

High-risk sexual behavior like sex work may be biologically linked to an increased risk of acquiring human immunodeficiency virus (HIV) and other sexually transmitted infections (STIs), new research at McMaster University has found.

6 Nov 2017

Scientists identify eight new genes involved in epileptic encephalopathy

Approximately 30 per cent of patients with epilepsy do not respond to anti-epileptic drugs. In these cases, all neurologists can do is attempt to find the right combination of medication through trial and error.

6 Nov 2017

Hormone stimulation for fertility preservation did not increase relapse rate in women with breast cancer

Women who received hormone stimulation for fertility preservation did not have a higher relapse rate in breast cancer compared with unexposed control women in a study from Karolinska Institutet in Sweden published in Breast Cancer Research and Treatment.

6 Nov 2017

Low-energy ESWT shows promise for managing digital ulcers in patients with systemic sclerosis

Extracorporeal shock-wave therapy at low energy levels showed promise as a new treatment for digital ulcers in patients with systemic sclerosis, or scleroderma, according to new research findings presented this week at the 2017 ACR/ARHP Annual Meeting in San Diego.

6 Nov 2017

Commonly prescribed medications may not benefit depressed CKD patients

A clinical trial involving hundreds of participants has shown that one of the most frequently prescribed antidepressants may not benefit millions of patients who also have chronic kidney disease (CKD).

3 Nov 2017

Pathology News and Research

Further Reading

Scientists identify critical player in Alzheimer's disease pathogenesis

Researchers use novel computational tool to understand complex disease processes

Breastfeeding may increase hay fever and eczema risk, but does not have clear effect on asthma

Scientists develop novel mouse model to capture pathology of sporadic ALS and FTD

Scientists identify new genes needed by Streptococcus pyogenes to grow in human saliva

OSA may put elderly people at increased risk of developing Alzheimer's disease

Common genetic fusion event could help identify patients with low-risk prostate cancer

Scientists to investigate potential role of airborne pollutants as triggers of Parkinson's disease

Novel mathematical model can predict how cancer patient will benefit from immunotherapies

Research suggests link between heart function and brain region critical for memory processing

Chronic liver inflammation promotes cancer by suppressing immunosurveillance, study finds

Early intervention may be crucial to successful treatment of Friedreich's ataxia

Penn Medicine to conduct Northeast’s first clinical trial of uterine transplants

Study finds link between increased brain glucose levels and Alzheimer's

Immune system plays surprising role in the aftermath of heart attacks, study finds

McMaster study: High-risk sexual behavior among women may increase risk of acquiring STIs

Scientists identify eight new genes involved in epileptic encephalopathy

Hormone stimulation for fertility preservation did not increase relapse rate in women with breast cancer

Low-energy ESWT shows promise for managing digital ulcers in patients with systemic sclerosis

Commonly prescribed medications may not benefit depressed CKD patients

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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