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Boehringer Ingelheim and Enleofen partner to develop anti-IL-11 therapies for multiple fibrotic disorders

Boehringer Ingelheim and Enleofen Bio Pte. Ltd. announced today the acquisition of worldwide exclusive rights to Enleofen’s preclinical interleukin-11 (IL-11) platform by Boehringer Ingelheim to develop first-in-class therapies across a broad range of fibro-inflammatory diseases.

From Boehringer Ingelheim International GmbH 14 Jan 2020

A New Discovery about MAIT Cells Sheds Light on Early-Phase HIV Infection

Researchers at the Karolinska Institutet, Sweden, have made an important discovery about a poorly understood group of immune cells (mucosa-associated invariant T [MAIT]cells) that could improve understanding of what happens during the initial stages of HIV infection.

14 Jan 2020

Study delineates the dynamic MAIT cell response during acute HIV infection

In a new study published in Nature Communications, researchers at Karolinska Institutet show that MAIT cells (mucosa-associated invariant T cells), part of the human immune system, respond with dynamic activity and reprogramming of gene expression during the initial phase of HIV infection.

14 Jan 2020

NAU scientists in search of a powerful combination of melanoma-fighting drugs

Melanoma is the most lethal type of skin cancer and unusually common in Arizona, where residents are exposed to higher-than-average amounts of ultraviolet radiation.

13 Jan 2020

Health benefits of a 'Dry January'

A new year often means a list of resolutions for change, such as abstaining from drinking alcohol, stopping smoking, or living a healthier lifestyle. For one, “Dry January” has become immensely popular because it motivates people to abstain from drinking alcohol for 30 days, at least.

13 Jan 2020

Researchers refine history and origins of common pathogens in human populations

An Italian research team has refined the history and origins of two extremely common pathogens in human populations, herpes simplex virus type 1 and type 2.

13 Jan 2020

Digital videos can be a vital source of cancer health education

Online health videos can be an important source of cancer education, according to Rutgers researchers. Their review, published in the Journal of Cancer Education, analyzed existing research to see how people obtained their cancer knowledge and how educational videos they watched prompted a change in their behavior.

12 Jan 2020

Melanoma patients report 95% satisfaction rate with Mohs surgery

Patients who received Mohs surgery to treat the most serious form of skin cancer, melanoma, reported a 95 percent long-term satisfaction rate with their results, according to a new study by UT Southwestern Medical Center dermatologists.

12 Jan 2020

Mount Sinai physicians emphasize the importance of early detection, treatment of thyroid disease

January is Thyroid Awareness Month, and physicians from the Hilda and J. Lester Gabrilove Division of Endocrinology, Diabetes and Bone Disease and the Department of Otolaryngology – Head and Neck Surgery at the Mount Sinai Health System are emphasizing the importance of being aware of symptoms that may be related to thyroid disease.

12 Jan 2020

High intake of aluminum compounds can cause potential health risks

In addition, the contributions of the various sources of total aluminum intake by the population were compared with one another. A high intake of aluminum compounds can cause, among other things, neurotoxic developmental disorders as well as damage the kidneys, liver and bones.

11 Jan 2020

Researchers analyze molecular characteristics of cerebrospinal fluid from LMM patients

Patients with advanced melanoma who develop metastases in the leptomeninges, the fluid filled membranes surrounding the brain and spinal cord, have an extremely dismal prognosis. Most patients only survive for 8 to 10 weeks after diagnosis.

11 Jan 2020

Scientists secure funding to develop better methods for evaluation of topically applied drugs

A team of leading scientists from Bath University UK, the UK's National Physical Laboratory, and the Colorado School of Mines USA has secured funding from the US Food and Drug Administration to develop better methods to assess the performance of topically applied drug products.

10 Jan 2020

Rejuvenating the BCG Vaccine

A new primate study published in the journal Nature in January 2020, reports that the almost century-old BCG vaccine against tuberculosis, may be used differently to achieve better protection against lung tuberculosis. While more work remains to be carried out before the findings can be accepted as the basis for clinical practice, they are extremely promising in the fight against this killer.

10 Jan 2020

Contaminating Fake Rubber Hand Aids People to Overcome Obsessive-Compulsive Disorder (OCD)

Obsessive-compulsive disorder (OCD) is a mental health condition wherein people are caught in a cycle of obsessions. The rubber hand illusion therapy, whereby fake rubber hands are contaminated with feces, maybe the key in helping people overcome their fears of touching contaminated surfaces, a new study suggests.

10 Jan 2020

Study: Understanding second-degree burns is key to treating these complications

New research shows how second-degree burns cause hard-to-treat chronic pain, and this understanding may be key to treating these complications, common in war veterans.

10 Jan 2020

Targeting VEGFA signaling in the epidermis can prevent psoriasis development

Psoriasis is a frequent skin inflammatory disorder affecting 3% of the population. Psoriasis is characterized by hyperproliferation and defect of epidermal differentiation, leading to the scaly appearance of the skin. The psoriasis skin also presents an increase in blood vessels, leading to the redness of the skin lesions and is associated with immune infiltration.

9 Jan 2020