Fibrosis News and Research

RSS

Fibrosis is the growth of fibrous tissue.

Deep Science Ventures and General Inception collaborate to create fibrosis-focused therapeutics company

Deep Science Ventures, a UK-based venture studio, and General Inception, a US-based venture studio, today announced a collaboration to create a company focused on developing novel treatments for fibrosis.

12 Dec 2024

Tea, apples, and chocolate proven to support liver health

A flavonoid-rich diet, including apples, tea, and dark chocolate, significantly lowers the risk of non-alcoholic fatty liver disease (NAFLD) and improves liver health biomarkers. These findings highlight the potential of dietary flavonoids in combating liver fat accumulation and inflammation.

9 Dec 2024

New compound HPH-15 offers promising alternative to diabetes medications

Kumamoto University scientists have unveiled a novel compound, HPH-15, with dual effects of reducing blood glucose levels and combating fat accumulation, marking a significant leap in diabetes treatment innovation.

6 Dec 2024

Study reveals pathways behind organ damage in severe COVID-19

New research published in the journal Proceedings of the National Academy of Sciences sheds light on the pathways that drive organ damage and death in severe COVID-19 and helps explain why survivors of the disease can experience long-term complications.

2 Dec 2024

Engineered stone countertop workers at risk for silicosis

Durable and attractive, engineered stone countertops are a popular feature in modern American kitchens, but the workers who build them are risking their health.

2 Dec 2024

Expert explores the expanding applications of GLP1 therapies

Researchers review recent advancements in glucagon-like peptide-1-based therapies.

28 Nov 2024

Novel mRNA-based therapy offers hope for patients with proliferative vitreoretinopathy

A new preclinical study by Mass Eye and Ear investigators showed that a novel mRNA-based therapy may be able to prevent blindness and scarring from proliferative vitreoretinopathy (PVR) following a retinal detachment repair or traumatic injury to the eye.

27 Nov 2024

Can fasting improve diabetes outcomes? Ramadan offers insights

A study during Ramadan shows intermittent fasting improves liver health, gut microbiota richness, and metabolic markers in T2DM patients. However, benefits fade quickly after fasting ends, highlighting the need for sustained interventions.

27 Nov 2024

Air pollution and cold temperatures drive bronchiectasis mortality in vulnerable populations

Researchers investigate how short-term exposure to ambient air pollution and temperature affects bronchiectasis mortality rates in China.

26 Nov 2024

Enterprise Therapeutics publishes on medicinal chemistry of ETD001, a novel inhaled ENaC blocker for treatment of cystic fibrosis

Enterprise Therapeutics Ltd (Enterprise), a biopharmaceutical company dedicated to the discovery and development of novel therapies to improve the lives of people with respiratory diseases, today announced the publication of a peer reviewed study in The European Journal of Medicinal Chemistry.

From Enterprise Therapeutics Ltd 25 Nov 2024

AI-designed drug ISM5939 granted IND clearance for cancer clinical trials

Insilico Medicine ("Insilico"), a clinical-stage generative artificial intelligence (AI)-driven drug discovery company, announced that it has received IND clearance from FDA for ISM5939, a potential best-in-class oral small molecule inhibitor targeting ENPP1 for the treatment of solid tumors.

22 Nov 2024

Nanomedicine using gas bubbles offers hope for lung cancer treatment

The delivery of nanomedicines using gas bubbles has shown itself to be a unique way of transporting cytotoxins to the lungs of cancer patients.

22 Nov 2024

SCimilarity revolutionizes single-cell data analysis with rapid cross-tissue comparisons

Researchers developed SCimilarity, a groundbreaking metric-learning framework, to rapidly analyze and compare single-cell data across tissues, diseases, and experimental conditions. This tool enables scalable discovery of shared cellular states and biological insights across the Human Cell Atlas.

21 Nov 2024

Growth hormone-releasing hormone transforms therapeutic potential in health and chronic disease

Researchers review the biological activities of growth hormone-releasing hormone and its analogs.

17 Nov 2024

Study focuses on COPD progression in younger populations

Researchers are exploring how small airway abnormalities in younger smokers could help identify who is at risk of developing COPD and establish how the chronic lung disease progresses, according to a new article.

15 Nov 2024

Researchers make progress toward inhalable mRNA medicines

Most people don't enjoy getting shots for treatments or vaccines. So, researchers are working to create more medicines, such as those made from messenger RNA (mRNA), that can be sprayed and inhaled.

14 Nov 2024

UAB researchers reverse liver disease in mice with gene therapy

UAB researchers have reversed metabolic dysfunction-associated steatohepatitis (MASH) in mouse models. MASH is a severe liver disease associated with obesity and type 2 diabetes that affects more than 40 million people.

13 Nov 2024

Study provides new insights into the central role of goblet cells

In a recent study, researchers at the University of California, San Diego, have provided new insights into the central role of goblet cells - specialized cells that line the gut - in maintaining a healthy and balanced immune environment within the gastrointestinal (GI) tract.

12 Nov 2024

HMGB1 as a key mediator in liver disease pathogenesis

Liver diseases, both acute and chronic, continue to pose significant clinical challenges due to high morbidity and mortality rates.

8 Nov 2024

Exploring the protective effects of HSD17B13 in hepatic steatosis

Chronic liver disease (CLD) is a growing global health challenge, accounting for millions of deaths each year. Its major contributors include metabolic dysfunction-associated steatohepatitis (MASH), alcoholic liver disease (ALD), and hepatitis C virus infection.

8 Nov 2024