Gastrointestinal Tract News and Research

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SARS-CoV-2 study in human gut organoids

Most of the major life-threatening symptoms of COVID-19 disease are associated with the host's generation of an exacerbated pro-inflammatory immune response. Many studies have correlated the intensity of the immune response with the severity of disease.

3 May 2021

Scientists develop an ultrasonic imaging system to visualize cell abnormalities in 3D

Scientists at the University of Nottingham have developed an ultrasonic imaging system, which can be deployed on the tip of a hair-thin optical fiber, and will be insertable into the human body to visualize cell abnormalities in 3D.

30 Apr 2021

New European research network addresses the effects of plastic particles on human health

Researching the effects of plastic particles on the human body and developing a health policy strategy for assessing the resulting risks is the goal of the new European research network PlasticsFatE. The University of Bayreuth, together with 26 other universities, institutes, and organizations from ten EU member states, is participating in the project.

29 Apr 2021

Study may provide a basis for oral insulin development using DNP peptides

Researchers from Kumamoto University, Japan have found that DNP peptide, a small intestine-permeable cyclic peptide originally used as an insulin additive to improve absorption into the small intestinal, lowers blood glucose levels in mice.

26 Apr 2021

New mathematical model could help design new probiotics and tailored diets to prevent diseases

A new mathematical model for the interaction of bacteria in the gut could help design new probiotics and specially tailored diets to prevent diseases. The research, from Chalmers University of Technology in Sweden, was recently published in the journal PNAS.

20 Apr 2021

Five-year study aims to improve health of patients with cystic fibrosis across their growing lifespan

People with cystic fibrosis are living better and longer, and now investigators want to further enhance quality and longevity by better understanding the role of nutrition, body composition and exercise in their health across an increasing lifespan.

19 Apr 2021

SARS-CoV-2 can alter bone marrow macrophage (BMM)-to-osteoclast differentiation, study finds

Now, a team of researchers in China and Australia has shown that SARS-CoV-2 infection can affect bone marrow macrophage (BMM)-to-osteoclast differentiation, which may impact the skeletal system.

16 Apr 2021

Oxford-AstraZeneca COVID vaccine induces cell spikes similar to SARS-CoV-2's

Scientists from the University of Oxford and the University of Southampton report in the journal ACS Central Science that cells infected with the ChAdOx1 vaccine produce spike proteins on the cells similar to those produced by natural SARS-CoV-2 infection.

9 Apr 2021

New guidelines recommend limited sugar intake to prevent impaired memory function in children

Sugar practically screams from the shelves of your grocery store, especially those products marketed to kids.

1 Apr 2021

Determination of vaccine-elicited SARS-CoV-2 antibodies in breastmilk

A new study has analyzed the levels of SARS-CoV-2 antibodies elicited by the novel COVID-19 vaccines in breastmilk.

30 Mar 2021

Microbiota modulation and re-establishment of eubiosis could help curb COVID-19 complications

In the paper published in the journal Frontiers in Immunology, the researchers noted that since both the respiratory tract and the gastrointestinal mucosa are affected in COVID-19, it is possible that adjunctive therapies that modulate the gut-lung axis.

18 Mar 2021

Antibodies to SARS-CoV-2 spike protein and RBD detected in saliva of mRNA-vaccine recipients

A team of researchers from the US and the Netherlands recently reported that antibodies to the spike protein and the RBD are detected in saliva samples from healthcare workers vaccinated with mRNA vaccines.

12 Mar 2021

Study rethinks the role of ACE2 in SARS-CoV-2 viral entry

Researchers in the US recently infected a series of human lung and head/neck cancer cell lines with SARS-CoV-2 that expressed varying levels of ACE2 and the TMPRSS2 protease to reassess their role in viral entrance.

8 Mar 2021

Reduced ambulatory function in cancer survivors associated with increased risk of death

Bottom Line: Cancer survivors had a greater risk of reduced ambulatory function, which was associated with an increased risk of death.

4 Mar 2021

SARS-CoV-2 viremia predicts severe COVID-19 disease outcomes

The SARS-CoV-2 plasma viremia has been linked to severe disease and death in COVID-19 cases in small-scale cohort studies. The current study, published on the pre-print server medRxiv, aimed to study the mechanisms behind this relationship.

2 Mar 2021

Cellular maps capture COVID-19 pathogenesis in detail

Researchers in the United States and Finland have used tissues from people who died from coronavirus disease 2019 (COVID-19) to generate detailed cellular maps of the pathogenetic processes that occur within affected organs during severe disease.

1 Mar 2021

Beneficial bacteria passed on to infants through breast milk change over time

The cocktail of beneficial bacteria passed from mother to infant through breast milk changes significantly over time and could act like a daily booster shot for infant immunity and metabolism.

23 Feb 2021

Specific cell-to-cell communication associated with progression of gastrointestinal stromal tumors

Gastrointestinal stromal tumors (GISTs) are a subytpe of cancers known as sarcomas. GIST is the most common type of sarcoma with approximately 5,000 to 6,000 new patient cases annually in the United States.

18 Feb 2021

Brain pericytes serve as a potential hub for SARS-CoV-2 infection

A team of scientists from the United States has recently conducted a study using pericyte-like cell-containing brain cortical organoids as an experimental model to investigate the impact of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection on the central nervous system.

11 Feb 2021

A new method to determine how carcinogenic bacteria reach their targets

The gram-negative bacteria Helicobacter pylori (H. pylori) colonize the stomachs of the majority of the world's population.