Pathology News and Research

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Pathology is the study and diagnosis of disease through examination of organs, tissues, bodily fluids, and whole bodies (autopsies). The term also encompasses the related scientific study of disease processes, called General pathology. Medical pathology is divided in two main branches, Anatomical pathology and Clinical pathology. Veterinary pathology is concerned with animal disease whereas Phytopathology is the study of plant diseases.

MD Anderson researchers chosen for national effort to expand reach of cancer immunotherapy

A major national effort to expand the reach of cancer immunotherapy to benefit more patients will draw upon the expertise of a team of researchers at The University of Texas MD Anderson Cancer Center.

13 Oct 2017

Researchers uncover enzyme behind immune cell response

Monash University researchers have revealed the role played by an enzyme that is pivotal to the process of clearing infection in the body.

12 Oct 2017

Combination of serrated polyps and high-risk adenomas may increase odds for colorectal cancer

Most colorectal cancer develops from precursors known as polyps, the most common and well researched of which are conventional adenomas. Conventional adenomas often progress to colorectal cancer through an intermediate step called high-risk adenomas.

11 Oct 2017

Calcium controls use of glucose by T cells to multiply and battle against infection, study finds

A calcium signal controls whether immune cells can use the nutrients needed to fuel their multiplication into a cellular army designed to fight invading viruses.

11 Oct 2017

New insights into rare-among-rare genetic bone disorder

I have been writing about conditions that cause out-of-place bone formation for over 10 years – since the discovery of the gene in 2006 for the rare bone disorder, FOP (fibrodysplasia ossificans progressive). But it was while interviewing geneticist Eileen Shore, PhD last spring about another bone disorder, progressive osseous heteroplasia, or POH, that it really hit me how much more rare POH is compared to FOP.

10 Oct 2017

Alzheimer's gene can protect against and promote neurological damage

Scientists drilling down to the molecular roots of Alzheimer's disease have encountered a good news/bad news scenario. A major player is a gene called TREM2, mutations of which can substantially raise a person's risk of the disease.

9 Oct 2017

UCLA scientists discover potential combination treatment for brain cancer in adults

UCLA scientists have discovered a potential combination treatment for glioblastoma, the deadliest form of brain cancer in adults. The three-year study led by Dr. David Nathanson, a member of UCLA's Jonsson Comprehensive Cancer Center, found that the drug combination tested in mice disrupts and exploits glucose intake, essentially cutting off the tumor's nutrients and energy supply.

9 Oct 2017

Researchers discover mutation that amplifies capabilities of tumor-suppressor protein

Cancer researchers have long hailed p53, a tumor-suppressor protein, for its ability to keep unruly cells from forming tumors. But for such a highly studied protein, p53 has hidden its tactics well.

9 Oct 2017

Genetic signature within prostate cancer cells can predict metastatic tumors

Many prostate cancers, which generally are diagnosed in older men, are "indolent," slow-growing tumors that aren't destined to be fatal. But some tumors are prone to becoming aggressive and spreading beyond the prostate, making them difficult to treat and life-threatening.

6 Oct 2017

CRI scientists challenge oldest concept in tumor metabolism

Scientists at the Children's Medical Center Research Institute at UT Southwestern (CRI) have discovered that lactate provides a fuel for growing tumors, challenging a nearly century-old observation known as the Warburg effect.

6 Oct 2017

Foods rich in potassium may help protect against vascular calcification

Bananas and avocados -- foods that are rich in potassium -- may help protect against pathogenic vascular calcification, also known as hardening of the arteries.

5 Oct 2017

Monoclonal antibody “cocktail” inhibits Zika infection, study reveals

A collaborative study conducted by the Miller School of Medicine, University of Miami has revealed that a monoclonal antibody “cocktail” inhibited zika virus (ZIKV) infection in primates.

5 Oct 2017

Researchers identify new cancer-causing pathway behind most aggressive type of leukemia

A team led by Massachusetts General Hospital (MGH) investigators has identified a new cancer-causing pathway behind most cases of an aggressive type of leukemia, findings that could lead to new targeted treatment approaches.

3 Oct 2017

New non-invasive biomarker detects Alzheimer's disease before occurrence of first symptoms

Absence of a prefrontal activation during sensory gating of simple tones detects the Alzheimer's disease (AD) before the occurrence of the first symptoms. Sanja Josef Golubic Ph.D., physicists at the Department of Physics, Faculty of Science, University of Zagreb, reveals the high potential, absolutely non-invasive biomarker of AD pathology in a new study published in the journal Human Brain Mapping. Josef Golubic found a discrete, individual biomarker of AD with "ideal" properties.

3 Oct 2017

Non-labeling multiphoton microscopy provides highly reliable prediction of cancer malignancy

A new study by Osaka University scientists shows that non-labeling multiphoton microscopy (NL-MPM) can be used for quantitative imaging of cancer that is safe and requires no resection, fixation or staining of tissues.

3 Oct 2017

Rapid, sensitive genetic test successfully detects some aggressive types of pancreatic cancer

A genetic test developed at UPMC proved highly sensitive at determining which pancreatic cysts are most likely to be associated with one of the most aggressive types of pancreatic cancer, UPMC and University of Pittsburgh School of Medicine scientists reported in Gut, the journal of the British Society of Gastroenterology.

3 Oct 2017

Proscia’s new product optimized for digital clinical workflows in anatomic pathology labs

Proscia announced today the launch of a new product optimized for digital clinical workflows in anatomic pathology labs. This new platform is set to transform the clinical use of digital pathology in commercial and hospital labs

30 Sep 2017

Reducing antioxidant levels in the colon may have positive effect on GI inflammation

A new study finds that lowering the levels of an antioxidant in the colon has an unexpectedly positive effect on gastrointestinal (GI) inflammation. The paper is published ahead of print in the American Journal of Physiology - Gastrointestinal and Liver Physiology.

28 Sep 2017

Researchers test way to stop or slow cardiac fibrosis after heart injury

Early research results suggest scientists might be on to a way to preserve heart function after heart attacks or for people with inherited heart defects called congenital cardiomyopathies.

28 Sep 2017

BD launches first automated phenotypic test for CPO detection

BD (Becton, Dickinson and Company), a leading global medical technology company, today announced the launch of the first automated phenotypic test to detect and classify carbapenemase-producing organisms (CPO).

From BD (Becton, Dickinson and Company) 28 Sep 2017

Pathology News and Research

Further Reading

MD Anderson researchers chosen for national effort to expand reach of cancer immunotherapy

Researchers uncover enzyme behind immune cell response

Combination of serrated polyps and high-risk adenomas may increase odds for colorectal cancer

Calcium controls use of glucose by T cells to multiply and battle against infection, study finds

New insights into rare-among-rare genetic bone disorder

Alzheimer's gene can protect against and promote neurological damage

UCLA scientists discover potential combination treatment for brain cancer in adults

Researchers discover mutation that amplifies capabilities of tumor-suppressor protein

Genetic signature within prostate cancer cells can predict metastatic tumors

CRI scientists challenge oldest concept in tumor metabolism

Foods rich in potassium may help protect against vascular calcification

Monoclonal antibody “cocktail” inhibits Zika infection, study reveals

Researchers identify new cancer-causing pathway behind most aggressive type of leukemia

New non-invasive biomarker detects Alzheimer's disease before occurrence of first symptoms

Non-labeling multiphoton microscopy provides highly reliable prediction of cancer malignancy

Rapid, sensitive genetic test successfully detects some aggressive types of pancreatic cancer

Proscia’s new product optimized for digital clinical workflows in anatomic pathology labs

Reducing antioxidant levels in the colon may have positive effect on GI inflammation

Researchers test way to stop or slow cardiac fibrosis after heart injury

BD launches first automated phenotypic test for CPO detection

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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